Two Sigma Investments
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Two Sigma Investments’s Intuitive Surgical ISRG Stock Holding History

Two Sigma Investments’s Portfolio ISRG Stock Details ISRG Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		$2.35M Buy
+5,100
New +$2.58M ﹤0.01% 2630
2022
Q1 		– Sell
-4,900
Closed -$1.76M – 3459
2021
Q4 		$1.76M Buy
+4,900
New +$1.69M ﹤0.01% 2037
2021
Q2 		– Sell
-9,000
Closed -$2.22M – 4295
2021
Q1 		$2.22M Buy
+9,000
New +$2.26M 0.01% 1622
2020
Q3 		– Sell
-6,000
Closed -$1.14M – 3307
2020
Q2 		$1.14M Sell
6,000
-31,500
-84% -$5.65M 0.01% 1457
2020
Q1 		$6.19M Buy
37,500
+26,400
+238% +$4.84M 0.05% 417
2019
Q4 		$2.19M Sell
11,100
-48,300
-81% -$9.04M 0.01% 1516
2019
Q3 		$10.7M Buy
59,400
+15,300
+35% +$2.65M 0.04% 523
2019
Q2 		$7.71M Buy
44,100
+19,500
+79% +$3.34M 0.03% 710
2019
Q1 		$4.68M Buy
+24,600
New +$4.37M 0.02% 1000
2018
Q4 		– Sell
-33,600
Closed -$6.43M – 3237
2018
Q3 		$6.43M Sell
33,600
-119,400
-78% -$21.2M 0.02% 836
2018
Q2 		$24.4M Buy
153,000
+89,100
+139% +$13.6M 0.07% 349
2018
Q1 		$8.79M Buy
+63,900
New +$8.92M 0.03% 652
2016
Q4 		– Sell
-9,000
Closed -$725K – 3301
2016
Q3 		$725K Sell
9,000
-54,000
-86% -$4.13M ﹤0.01% 2200
2016
Q2 		$4.63M Buy
+63,000
New +$4.43M 0.02% 805
2016
Q1 		– Sell
-18,000
Closed -$1.09M – 2948
2015
Q4 		$1.09M Buy
+18,000
New +$1.01M 0.01% 1440

Other funds holding ISRG

BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
VCM
Vanguard Capital Management Malvern, Pennsylvania $4.04T AUM
State Street
State Street Boston, Massachusetts $2.9T AUM 29.55% 1-Year Est. Return
T. Rowe Price Associates
T. Rowe Price Associates Baltimore, Maryland $865B AUM 30.76% 1-Year Est. Return
Invesco
Invesco Atlanta, Georgia $1.02T AUM 30.18% 1-Year Est. Return
Geode Capital Management
Geode Capital Management Boston, Massachusetts $1.61T AUM 30.72% 1-Year Est. Return
Capital World Investors
Capital World Investors Los Angeles, California $733B AUM 35.63% 1-Year Est. Return
VPM
Vanguard Portfolio Management Malvern, Pennsylvania $1.91T AUM
Morgan Stanley
Morgan Stanley New York $1.66T AUM 25.57% 1-Year Est. Return
Fidelity Investments
Fidelity Investments Boston, Massachusetts $1.9T AUM 41.92% 1-Year Est. Return

Two Sigma Investments's ISRG Position: Q1 2026 in Review

Two Sigma Investments increased its Intuitive Surgical (ISRG) stake by 206% in Q1 2026, buying an estimated $478M and bringing the position to 1,405,334 shares worth $648M. The position accounts for 0.52% of the portfolio, ranked #22.

Two Sigma Investments first reported a position in ISRG in Q2 2013 and has held it in 45 quarters since. 2,303 funds tracked by Wall St. Rank hold ISRG as of Q1 2026.

  • Two Sigma Investments held 1,405,334 shares of Intuitive Surgical worth $648M as of Q1 2026.
  • Two Sigma Investments bought 945,455 Intuitive Surgical shares in Q1 2026, an estimated $478M.
  • Intuitive Surgical made up 0.52% of Two Sigma Investments's portfolio in Q1 2026, its #22 holding.
  • Two Sigma Investments first reported a position in Intuitive Surgical in Q2 2013 and has held it in 45 quarters since.
  • 2,303 funds tracked by Wall St. Rank held Intuitive Surgical as of Q1 2026.

Based on Two Sigma Investments's 13F filing for Q1 2026, filed 15 May 2026.