Two Sigma Investments’s Intuitive Surgical ISRG Stock Holding History

Two Sigma Investments’s Portfolio ISRG Stock Details ISRG Fund Activity

Bought

Maintained

Sold

Quarter	Market Value	Status	Shares	Change in Stake	Trade Value	Portfolio Weight	Portfolio Position
2026 Q1	$1.43M	Buy	+3,100	New	+$1.57M	﹤0.01%	3005
2022 Q1	–	Sell	-2,300	Closed	-$826K	–	3458
2021 Q4	$826K	Buy	+2,300	New	+$791K	﹤0.01%	2732
2020 Q3	–	Sell	-3,000	Closed	-$570K	–	3306
2020 Q2	$570K	Sell	3,000 -22,500	-88%	-$4.03M	﹤0.01%	1911
2020 Q1	$4.21M	Sell	25,500 -4,500	-15%	-$824K	0.03%	578
2019 Q4	$5.91M	Sell	30,000 -15,300	-34%	-$2.86M	0.02%	867
2019 Q3	$8.15M	Buy	45,300 +2,400	+6%	+$415K	0.03%	633
2019 Q2	$7.5M	Buy	42,900 +18,300	+74%	+$3.14M	0.03%	720
2019 Q1	$4.68M	Buy	+24,600	New	+$4.37M	0.02%	999
2018 Q4	–	Sell	-24,000	Closed	-$4.59M	–	3235
2018 Q3	$4.59M	Sell	24,000 -129,000	-84%	-$22.9M	0.01%	990
2018 Q2	$24.4M	Buy	153,000 +82,500	+117%	+$12.6M	0.07%	348
2018 Q1	$9.7M	Buy	+70,500	New	+$9.84M	0.03%	601
2016 Q4	–	Sell	-11,700	Closed	-$942K	–	3300
2016 Q3	$942K	Sell	11,700 -42,300	-78%	-$3.24M	﹤0.01%	1999
2016 Q2	$3.97M	Buy	+54,000	New	+$3.8M	0.02%	871
2016 Q1	–	Sell	-18,000	Closed	-$1.09M	–	2947
2015 Q4	$1.09M	Buy	+18,000	New	+$1.01M	0.01%	1439

Other funds holding ISRG

BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return

VCM

Vanguard Capital Management Malvern, Pennsylvania $4.04T AUM

State Street Boston, Massachusetts $2.9T AUM 29.55% 1-Year Est. Return

T. Rowe Price Associates Baltimore, Maryland $865B AUM 30.76% 1-Year Est. Return

Invesco Atlanta, Georgia $1.02T AUM 30.18% 1-Year Est. Return

Geode Capital Management Boston, Massachusetts $1.61T AUM 30.72% 1-Year Est. Return

Capital World Investors Los Angeles, California $733B AUM 35.63% 1-Year Est. Return

VPM

Vanguard Portfolio Management Malvern, Pennsylvania $1.91T AUM

Morgan Stanley New York $1.66T AUM 25.57% 1-Year Est. Return

Fidelity Investments Boston, Massachusetts $1.9T AUM 41.92% 1-Year Est. Return

Two Sigma Investments's ISRG Position: Q1 2026 in Review

Two Sigma Investments increased its Intuitive Surgical (ISRG) stake by 206% in Q1 2026, buying an estimated $478M and bringing the position to 1,405,334 shares worth $648M. The position accounts for 0.52% of the portfolio, ranked #22.

Two Sigma Investments first reported a position in ISRG in Q2 2013 and has held it in 45 quarters since. 2,303 funds tracked by Wall St. Rank hold ISRG as of Q1 2026.

Two Sigma Investments held 1,405,334 shares of Intuitive Surgical worth $648M as of Q1 2026.
Two Sigma Investments bought 945,455 Intuitive Surgical shares in Q1 2026, an estimated $478M.
Intuitive Surgical made up 0.52% of Two Sigma Investments's portfolio in Q1 2026, its #22 holding.
Two Sigma Investments first reported a position in Intuitive Surgical in Q2 2013 and has held it in 45 quarters since.
2,303 funds tracked by Wall St. Rank held Intuitive Surgical as of Q1 2026.

Based on Two Sigma Investments's 13F filing for Q1 2026, filed 15 May 2026.