Intuitive Surgical
ISRG
2,419 hedge funds and large institutions have $173B invested in Intuitive Surgical in 2025 Q4 according to their latest regulatory filings, with 459 funds opening new positions, 976 increasing their positions, 715 reducing their positions, and 110 closing their positions.
317% more first-time investments, than exits
New positions opened: 459 | Existing positions closed: 110
41% more funds holding in top 10
Funds holding in top 10: 49 → 69 (+20)
37% more repeat investments, than reductions
Existing positions increased: 976 | Existing positions reduced: 715
33% more capital invested
Capital invested by funds: $130B → $173B (+$43B)
14% more funds holding
Funds holding: 2,116 → 2,419 (+303)
3.71% more ownership
Funds ownership: 81.81% → 85.52% (+3.7%)
22% less call options, than puts
Call options by funds: $2.09B | Put options by funds: $2.69B
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
Invesco
Atlanta,
Georgia
|
+$4.57B |
| 2 |
Fidelity Investments
Boston,
Massachusetts
|
+$840M |
| 3 |
Millennium Management
New York
|
+$653M |
| 4 |
Polen Capital Management
Boca Raton,
Florida
|
+$449M |
| 5 |
Assenagon Asset Management
Senningerberg,
Luxembourg
|
+$421M |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
BlackRock
New York
|
-$547M |
| 2 |
Amundi
Paris,
France
|
-$528M |
| 3 |
RIM
Rakuten Investment Management
Tokyo,
Japan
|
-$427M |
| 4 |
Goldman Sachs
New York
|
-$383M |
| 5 |
D.E. Shaw & Co
New York
|
-$379M |
ISRG Hedge Fund Activity: Q4 2025 in Review
2,419 of the 8,284 institutional investors tracked by Wall St. Rank reported a position in Intuitive Surgical (ISRG) for Q4 2025, worth a combined $173B — up 33% from $130B a quarter earlier.
Buyers outnumbered sellers: 459 funds opened new ISRG positions and 110 closed out — a net gain of 349 holders — while 976 added to existing stakes and 715 trimmed.
The largest buyer was Invesco, adding an estimated $4.57B. The largest seller was BlackRock, cutting an estimated $547M.
- 2,419 institutional investors held Intuitive Surgical (ISRG) as of Q4 2025, up from 2,116 in Q3 2025.
- Funds reported $173B of Intuitive Surgical stock for Q4 2025, up 33% quarter-over-quarter.
- 459 funds opened new Intuitive Surgical positions in Q4 2025 and 110 closed out, a net change of +349 holders.
- The largest Intuitive Surgical buyer in Q4 2025 was Invesco, an estimated $4.57B added.
- The largest Intuitive Surgical seller in Q4 2025 was BlackRock, an estimated $547M sold.
Based on aggregated 13F filings for Q4 2025.