Two Sigma Advisers
APLT

Two Sigma Advisers’s Applied Therapeutics APLT Stock Holding History

Two Sigma Advisers’s Portfolio APLT Stock Details APLT Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2025
Q3 		– Sell
-303,900
Closed -$94.5K – 2344
2025
Q2 		$94.5K Sell
303,900
-354,500
-54% -$137K ﹤0.01% 2213
2025
Q1 		$322K Buy
+658,400
New +$388K ﹤0.01% 1961
2024
Q1 		– Sell
-51,000
Closed -$171K – 2446
2023
Q4 		$171K Buy
51,000
+35,400
+227% +$88.1K ﹤0.01% 2261
2023
Q3 		$38.8K Sell
15,600
-91,071
-85% -$150K ﹤0.01% 2296
2023
Q2 		$137K Sell
106,671
-43,116
-29% -$57.2K ﹤0.01% 2163
2023
Q1 		$121K Sell
149,787
-100,113
-40% -$98.6K ﹤0.01% 2354
2022
Q4 		$190K Buy
249,900
+700
+0.3% +$554 ﹤0.01% 2203
2022
Q3 		$232K Buy
249,200
+136,800
+122% +$164K ﹤0.01% 2154
2022
Q2 		$107K Buy
112,400
+7,300
+7% +$12K ﹤0.01% 2384
2022
Q1 		$222K Buy
105,100
+92,200
+715% +$247K ﹤0.01% 2350
2021
Q4 		$115K Buy
12,900
+2,500
+24% +$32.8K ﹤0.01% 2393
2021
Q3 		$173K Buy
+10,400
New +$180K ﹤0.01% 2273

Other funds holding APLT

T. Rowe Price Investment Management
T. Rowe Price Investment Management Baltimore, Maryland $145B AUM 22.78% 1-Year Est. Return
VPC
Vestal Point Capital New York $3.58B AUM 189.12% 1-Year Est. Return
PBM
Propel Bio Management Los Angeles, California $159M AUM 60.94% 1-Year Est. Return
KCM
Knoll Capital Management Miami, Florida $180M AUM 66.11% 1-Year Est. Return
Vanguard Group
Vanguard Group Malvern, Pennsylvania $6.9T AUM 27.45% 1-Year Est. Return
SAM
Simplify Asset Management Las Vegas, Nevada $7.19B AUM 6.88% 1-Year Est. Return
BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
PNC Financial Services Group
PNC Financial Services Group Pittsburgh, Pennsylvania $202B AUM 37.79% 1-Year Est. Return
Pathstone Holdings
Pathstone Holdings Englewood, New Jersey $25.1B AUM 22.95% 1-Year Est. Return
Marshall Wace
Marshall Wace London, United Kingdom $100B AUM 35.1% 1-Year Est. Return

Two Sigma Advisers's APLT Position: Q3 2025 in Review

Two Sigma Advisers sold out of Applied Therapeutics (APLT) in Q3 2025, closing a stake of 303,900 shares — an estimated $94.5K sold.

Two Sigma Advisers first reported a position in APLT in Q3 2021 and held it in 12 quarters. The position peaked at $322K in Q1 2025. 70 funds tracked by Wall St. Rank hold APLT as of Q3 2025.

  • Two Sigma Advisers reported no remaining Applied Therapeutics position as of Q3 2025 after selling out during the quarter.
  • Two Sigma Advisers sold 303,900 Applied Therapeutics shares in Q3 2025, an estimated $94.5K.
  • Two Sigma Advisers first reported a position in Applied Therapeutics in Q3 2021 and held it in 12 quarters.
  • Two Sigma Advisers's Applied Therapeutics position peaked at $322K in Q1 2025.
  • 70 funds tracked by Wall St. Rank held Applied Therapeutics as of Q3 2025.

Based on Two Sigma Advisers's 13F filing for Q3 2025, filed 14 Nov 2025.