Simplify Asset Management’s Applied Therapeutics APLT Stock Holding History

Simplify Asset Management’s Portfolio APLT Stock Details APLT Fund Activity

Bought

Maintained

Sold

Quarter	Market Value	Status	Shares	Change in Stake	Trade Value	Portfolio Weight	Portfolio Position
2025 Q4	–	Sell	-4,487,505	Closed	-$2.71M	–	145
2025 Q3	$2.71M	Hold	4,487,505	–	–	0.05%	43
2025 Q2	$1.4M	Hold	4,487,505	–	–	0.07%	51
2025 Q1	$2.19M	Buy	4,487,505 +1,670,000	+59%	+$983K	0.08%	44
2024 Q4	$2.41M	Hold	2,817,505	–	–	0.12%	46
2024 Q3	$23.9M	Hold	2,817,505	–	–	1.12%	15
2024 Q2	$13.2M	Hold	2,817,505	–	–	0.88%	17
2024 Q1	$19.2M	Buy	2,817,505 +400,000	+17%	+$1.8M	1.14%	12
2023 Q4	$8.1M	Hold	2,417,505	–	–	0.73%	12
2023 Q3	$6.02M	Buy	2,417,505 +34,884	+1%	+$57.5K	0.69%	15
2023 Q2	$3.05M	Hold	2,382,621	–	–	0.4%	29
2023 Q1	$1.93M	Buy	+2,382,621	New	+$2.35M	0.28%	39

Other funds holding APLT

T. Rowe Price Investment Management Baltimore, Maryland $145B AUM 22.78% 1-Year Est. Return

Vanguard Group Malvern, Pennsylvania $6.9T AUM 27.45% 1-Year Est. Return

KCM

Knoll Capital Management Miami, Florida $180M AUM 66.11% 1-Year Est. Return

DAM

Deltec Asset Management New York $677M AUM 31.67% 1-Year Est. Return

BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return

Pathstone Holdings Englewood, New Jersey $25.1B AUM 22.95% 1-Year Est. Return

Renaissance Technologies New York $63.9B AUM 45.56% 1-Year Est. Return

Jane Street New York $777B AUM 61.18% 1-Year Est. Return

Geode Capital Management Boston, Massachusetts $1.61T AUM 30.72% 1-Year Est. Return

Adage Capital Partners Boston, Massachusetts $64.8B AUM 42.7% 1-Year Est. Return

Simplify Asset Management's APLT Position: Q4 2025 in Review

Simplify Asset Management sold out of Applied Therapeutics (APLT) in Q4 2025, closing a stake of 4,487,505 shares — an estimated $2.71M sold.

Simplify Asset Management first reported a position in APLT in Q1 2023 and held it in 11 quarters. The position peaked at $23.9M in Q3 2024. 52 funds tracked by Wall St. Rank hold APLT as of Q4 2025.

Simplify Asset Management reported no remaining Applied Therapeutics position as of Q4 2025 after selling out during the quarter.
Simplify Asset Management sold 4,487,505 Applied Therapeutics shares in Q4 2025, an estimated $2.71M.
Simplify Asset Management first reported a position in Applied Therapeutics in Q1 2023 and held it in 11 quarters.
Simplify Asset Management's Applied Therapeutics position peaked at $23.9M in Q3 2024.
52 funds tracked by Wall St. Rank held Applied Therapeutics as of Q4 2025.

Based on Simplify Asset Management's 13F filing for Q4 2025, filed 9 Feb 2026.