Squarepoint
OMER icon

Squarepoint’s Omeros OMER Stock Holding History

Squarepoint’s Portfolio OMER Stock Details OMER Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2025
Q4 		– Sell
-155,496
Closed -$638K – 4704
2025
Q3 		$638K Buy
155,496
+67,021
+76% +$266K ﹤0.01% 3040
2025
Q2 		$265K Buy
88,475
+64,571
+270% +$322K ﹤0.01% 3779
2025
Q1 		$196K Sell
23,904
-8,105
-25% -$71.5K ﹤0.01% 4020
2024
Q4 		$316K Sell
32,009
-15,355
-32% -$105K ﹤0.01% 4108
2024
Q3 		$188K Buy
+47,364
New +$202K ﹤0.01% 3706
2024
Q1 		– Sell
-37,512
Closed -$123K – 4434
2023
Q4 		$123K Sell
37,512
-24,351
-39% -$51.4K ﹤0.01% 3718
2023
Q3 		$181K Buy
61,863
+32,181
+108% +$129K ﹤0.01% 3442
2023
Q2 		$161K Sell
29,682
-59,494
-67% -$347K ﹤0.01% 3274
2023
Q1 		$415K Buy
+89,176
New +$322K ﹤0.01% 2400
2022
Q3 		– Sell
-39,177
Closed -$108K – 3301
2022
Q2 		$108K Buy
+39,177
New +$133K ﹤0.01% 2607
2022
Q1 		– Sell
-19,961
Closed -$128K – 3326
2021
Q4 		$128K Buy
+19,961
New +$145K ﹤0.01% 2858
2021
Q3 		– Sell
-18,857
Closed -$280K – 3273
2021
Q2 		$280K Buy
+18,857
New +$316K ﹤0.01% 2590
2021
Q1 		– Sell
-31,433
Closed -$449K – 3477
2020
Q4 		$449K Sell
31,433
-13,958
-31% -$171K ﹤0.01% 1892
2020
Q3 		$459K Buy
+45,391
New +$584K 0.01% 1496
2020
Q2 		– Sell
-67,026
Closed -$896K – 2434
2020
Q1 		$896K Buy
67,026
+43,100
+180% +$573K 0.02% 764
2019
Q4 		$337K Buy
23,926
+10,773
+82% +$158K ﹤0.01% 1980
2019
Q3 		$215K Buy
+13,153
New +$226K ﹤0.01% 2048
2017
Q2 		– Sell
-19,606
Closed -$296K – 1729
2017
Q1 		$296K Sell
19,606
-16,239
-45% -$178K 0.01% 1082
2016
Q4 		$356K Buy
+35,845
New +$366K 0.01% 1045

Other funds holding OMER

BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
Vanguard Group
Vanguard Group Malvern, Pennsylvania $6.9T AUM 27.45% 1-Year Est. Return
ISL
Ingalls & Snyder LLC New York $2.83B AUM 21.61% 1-Year Est. Return
UBS Group
UBS Group Zurich, Switzerland $666B AUM 30.12% 1-Year Est. Return
Stifel Financial
Stifel Financial St. Louis, Missouri $109B AUM 21.36% 1-Year Est. Return
Geode Capital Management
Geode Capital Management Boston, Massachusetts $1.61T AUM 30.72% 1-Year Est. Return
State Street
State Street Boston, Massachusetts $2.9T AUM 29.55% 1-Year Est. Return
Corient Private Wealth
Corient Private Wealth Miami, Florida $69.9B AUM 22.19% 1-Year Est. Return
KK
Kotler Kevin $427M AUM
D.E. Shaw & Co
D.E. Shaw & Co New York $166B AUM 43.98% 1-Year Est. Return

Squarepoint's OMER Position: Q4 2025 in Review

Squarepoint sold out of Omeros (OMER) in Q4 2025, closing a stake of 155,496 shares — an estimated $638K sold.

Squarepoint first reported a position in OMER in Q4 2016 and held it in 19 quarters. The position peaked at $896K in Q1 2020. 149 funds tracked by Wall St. Rank hold OMER as of Q4 2025.

  • Squarepoint reported no remaining Omeros position as of Q4 2025 after selling out during the quarter.
  • Squarepoint sold 155,496 Omeros shares in Q4 2025, an estimated $638K.
  • Squarepoint first reported a position in Omeros in Q4 2016 and held it in 19 quarters.
  • Squarepoint's Omeros position peaked at $896K in Q1 2020.
  • 149 funds tracked by Wall St. Rank held Omeros as of Q4 2025.

Based on Squarepoint's 13F filing for Q4 2025, filed 13 Feb 2026.