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Simplify Asset Management Portfolio holdings

AUM $7.19B
1-Year Est. Return 6.88%
This Fund
S&P 500
This Quarter Est. Return
+3.54%
1 Year Est. Return
+6.88%
3 Year Est. Return
+44.98%
5 Year Est. Return
+50.08%
10 Year Est. Return
AUM
$5.43B
AUM Growth
+$3.44B
Cap. Flow
+$3.3B
Cap. Flow %
60.81%
Top 10 Hldgs %
93.71%
Holding
138
New
49
Increased
45
Reduced
22
Closed
9

Sector Composition

Rank Sector Weight
1 Healthcare 3.3%
2 Energy 0.44%
3 Consumer Discretionary 0.33%
4 Technology 0.18%
5 Industrials 0.16%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake
Capital Flow
GILD icon
26
Gilead Sciences
GILD
$167B
$6.68M 0.12%
60,186
+7,296
+14% +$829K
CVS icon
27
CVS Health
CVS
$137B
$6.4M 0.12%
84,926
+37,960
+81% +$2.6M
TSLL icon
28
Direxion Daily TSLA Bull 2X ETF
TSLL
$3.74B
$6.36M 0.12%
+301,237
New +$4.08M
ARQT icon
29
Arcutis Biotherapeutics
ARQT
$3.56B
$5.99M 0.11%
317,997
-91,435
-22% -$1.44M
EYE icon
30
National Vision
EYE
$1.66B
$5.77M 0.11%
197,840
-83,371
-30% -$2.05M
MIST icon
31
Milestone Pharmaceuticals
MIST
$148M
$5.67M 0.1%
2,832,974
+1,842,974
+186% +$3.24M
ABVX
32
Abivax
ABVX
$11.9B
$5.22M 0.1%
+61,449
New +$3.77M
NBIX icon
33
Neurocrine Biosciences
NBIX
$17.2B
$5.14M 0.09%
36,624
-9,873
-21% -$1.34M
NKTR icon
34
Nektar Therapeutics
NKTR
$2.31B
$4.96M 0.09%
87,174
+35,176
+68% +$1.16M
PHAT icon
35
Phathom Pharmaceuticals
PHAT
$873M
$3.79M 0.07%
321,935
-200,000
-38% -$2.06M
ACHV icon
36
Achieve Life Sciences
ACHV
$644M
$3.73M 0.07%
1,184,512
ISRG icon
37
Intuitive Surgical
ISRG
$122B
$3.42M 0.06%
7,640
-1,059
-12% -$508K
MRUS
38
DELISTED
Merus
MRUS
$3.14M 0.06%
+33,314
New +$2.17M
ABEO icon
39
Abeona Therapeutics
ABEO
$399M
$2.98M 0.05%
565,009
+6,425
+1% +$40.7K
AZN icon
40
AstraZeneca
AZN
$262B
$2.83M 0.05%
18,472
+2,246
+14% +$340K
INSM icon
41
Insmed
INSM
$23.5B
$2.83M 0.05%
19,664
+4,128
+27% +$506K
DCTH icon
42
Delcath Systems
DCTH
$442M
$2.81M 0.05%
261,126
+154,497
+145% +$1.73M
APLT
43
DELISTED
Applied Therapeutics
APLT
$2.71M 0.05%
4,487,505
LITL
44
Simplify Piper Sandler US Small-Cap PLUS Income ETF
LITL
$6.87M
$2.61M 0.05%
91,464
APLS
45
DELISTED
Apellis Pharmaceuticals
APLS
$2.42M 0.04%
+106,888
New +$2.49M
ALHC icon
46
Alignment Healthcare
ALHC
$4.26B
$2.39M 0.04%
136,934
+16,613
+14% +$246K
COR icon
47
Cencora
COR
$59.9B
$2.31M 0.04%
7,406
-1,347
-15% -$396K
CLDX icon
48
Celldex Therapeutics
CLDX
$2.77B
$2.2M 0.04%
+85,000
New +$1.97M
TYA icon
49
Simplify Intermediate Term Treasury Futures Strategy ETF
TYA
$65.2M
$2.16M 0.04%
158,400
-2,863,782
-95% -$38.5M
MSOS icon
50
AdvisorShares Pure US Cannabis ETF
MSOS
$905M
$2.13M 0.04%
+444,428
New +$1.75M

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Simplify Asset Management's Q3 2025 Portfolio in Review

As of Q3 2025, Simplify Asset Management held 138 positions worth $5.43B, up 173% from $1.99B the previous quarter. Its ten largest holdings account for 94% of the portfolio.

Simplify Asset Management deployed $3.3B of net new capital in Q3 2025, opening 49 new positions and adding to 45 existing holdings. Its largest new stake was Simplify Government Money Market ETF: 33,159,700 shares worth $3.32B.

By sector, the portfolio is most concentrated in Healthcare at 3.3% of assets, down from 6.5% a quarter earlier, followed by Energy and Consumer Discretionary.

On the sell side, the largest reduction was iShares Core S&P 500 ETF, an estimated $77M trimmed.

  • Simplify Asset Management's largest Q3 2025 buy was Simplify Government Money Market ETF: 33,159,700 shares worth $3.32B.
  • Simplify Asset Management added most to Simplify Next Intangible Core Index ETF in Q3 2025, an estimated $25M increase.
  • Simplify Asset Management's biggest Q3 2025 reduction was iShares Core S&P 500 ETF, cutting an estimated $77M.
  • Simplify Asset Management fully exited ADMA Biologics in Q3 2025, selling an estimated $6.94M.
  • Simplify Asset Management's ten largest holdings make up 94% of its $5.43B portfolio in Q3 2025.
  • Simplify Asset Management opened 49 new positions and closed 9 in Q3 2025.
  • Simplify Asset Management's portfolio value rose 173% quarter-over-quarter to $5.43B.

Based on Simplify Asset Management's 13F filing for Q3 2025, filed 20 Oct 2025.