SEI Investments’s Amylyx Pharmaceuticals AMLX Stock Holding History

SEI Investments’s Portfolio AMLX Stock Details AMLX Fund Activity

Bought

Maintained

Sold

Quarter	Market Value	Status	Shares	Change in Stake	Trade Value	Portfolio Weight	Portfolio Position
2026 Q2	$355K	Sell	19,750 -65,529	-77%	-$1.01M	﹤0.01%	2787
2026 Q1	$1.19M	Buy	85,279 +32,423	+61%	+$456K	﹤0.01%	2273
2025 Q4	$639K	Buy	+52,856	New	+$718K	﹤0.01%	2398
2023 Q2	–	Sell	-69,665	Closed	-$2.04M	–	2671
2023 Q1	$2.04M	Buy	69,665 +55,888	+406%	+$1.94M	﹤0.01%	1609
2022 Q4	$509K	Sell	13,777 -49,897	-78%	-$1.77M	﹤0.01%	1994
2022 Q3	$1.79M	Sell	63,674 -30,180	-32%	-$753K	﹤0.01%	1591
2022 Q2	$1.81M	Buy	+93,854	New	+$1.11M	﹤0.01%	1604

Other funds holding AMLX

Fidelity Investments Boston, Massachusetts $2.3T AUM 54.33% 1-Year Est. Return

BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return

Perceptive Advisors New York $6.66B AUM 360.84% 1-Year Est. Return

TCM

TCG Crossover Management Palo Alto, California $4.16B AUM 983.43% 1-Year Est. Return

Commodore Capital New York $1.68B AUM 375.52% 1-Year Est. Return

Jupiter Topco New York $245B AUM

SVCM

Saturn V Capital Management Austin, Texas $697M AUM 628.57% 1-Year Est. Return

Vanguard Capital Management Malvern, Pennsylvania $4.68T AUM

Morgan Stanley New York $1.89T AUM 35.08% 1-Year Est. Return

DCM

Driehaus Capital Management Chicago, Illinois $17.3B AUM 211.34% 1-Year Est. Return

SEI Investments's AMLX Position: Q2 2026 in Review

SEI Investments reduced its Amylyx Pharmaceuticals (AMLX) stake by 77% in Q2 2026, selling an estimated $1.01M and leaving 19,750 shares worth $355K. The position accounts for ﹤0.01% of the portfolio, ranked #2787.

SEI Investments first reported a position in AMLX in Q2 2022 and has held it in 7 quarters since. The position peaked at $2.04M in Q1 2023. 206 funds tracked by Wall St. Rank hold AMLX as of Q2 2026.

SEI Investments held 19,750 shares of Amylyx Pharmaceuticals worth $355K as of Q2 2026.
SEI Investments sold 65,529 Amylyx Pharmaceuticals shares in Q2 2026, an estimated $1.01M.
Amylyx Pharmaceuticals made up ﹤0.01% of SEI Investments's portfolio in Q2 2026, its #2787 holding.
SEI Investments first reported a position in Amylyx Pharmaceuticals in Q2 2022 and has held it in 7 quarters since.
SEI Investments's Amylyx Pharmaceuticals position peaked at $2.04M in Q1 2023.
206 funds tracked by Wall St. Rank held Amylyx Pharmaceuticals as of Q2 2026.

Based on SEI Investments's 13F filing for Q2 2026, filed 14 Aug 2026.