O

OrbiMed Portfolio holdings

AUM $3.98B
This Quarter Return
+33.33%
1 Year Return
+13.05%
3 Year Return
+159.74%
5 Year Return
+207.27%
10 Year Return
+1,027.33%
AUM
$6.38B
AUM Growth
+$6.38B
Cap. Flow
-$261M
Cap. Flow %
-4.1%
Top 10 Hldgs %
40.48%
Holding
147
New
18
Increased
25
Reduced
26
Closed
25

Top Buys

1
ALEC icon
Alector
ALEC
$247M
2
NBIX icon
Neurocrine Biosciences
NBIX
$118M
3
TEVA icon
Teva Pharmaceuticals
TEVA
$64M
4
AVDR
Avedro, Inc Common Stock
AVDR
$52M
5
ENDP
Endo International plc
ENDP
$49.5M

Top Sells

1
CELG
Celgene Corp
CELG
$279M
2
BIIB icon
Biogen
BIIB
$177M
3
AGN
Allergan plc
AGN
$128M
4
CVS icon
CVS Health
CVS
$52M
5
CNC icon
Centene
CNC
$48.1M

Sector Composition

1 Healthcare 96.73%
2 Financials 1.15%
Name Market Value Portfolio Weight Shares or Principal Shares
Change % 		Capital Flow
NVTA
101
DELISTED
Invitae Corporation
NVTA
$5.2M 0.08%
222,017
-602,532
-73% -$14.1M
VYNE icon
102
VYNE Therapeutics
VYNE
$8.09M
$4.98M 0.08%
+8,804
New +$4.98M
CTIC
103
DELISTED
CTI BioPharma Corp. (DE) Common Stock
CTIC
$4.85M 0.08%
5,000,000
– –
WHWK
104
Whitehawk Therapeutics, Inc. Common Stock
WHWK
$85.3M
$4.68M 0.07%
346,263
– –
TECX
105
Tectonic Therapeutic, Inc. Common Stock
TECX
$305M
$4.38M 0.07%
16,549
-4,276
-21% -$1.13M
RLM
106
DELISTED
Realm Therapeutics plc American Depositary Shares
RLM
$3.93M 0.06%
1,021,484
– –
NVTR
107
DELISTED
Nuvectra Corporation Common Stock
NVTR
$3.85M 0.06%
350,000
– –
AERI
108
DELISTED
Aerie Pharmaceuticals, Inc.
AERI
$2.76M 0.04%
58,000
-814,100
-93% -$38.7M
KALV icon
109
KalVista Pharmaceuticals
KALV
$713M
$2.59M 0.04%
+90,500
New +$2.59M
KRYS icon
110
Krystal Biotech
KRYS
$4.35B
$1.95M 0.03%
+59,210
New +$1.95M
MRNS
111
DELISTED
Marinus Pharmaceuticals, Inc
MRNS
$1.66M 0.03%
99,525
-25,000
-20% -$418K
SNDX icon
112
Syndax Pharmaceuticals
SNDX
$1.39B
$1.11M 0.02%
212,000
– –
SRRA
113
DELISTED
Sierra Oncology, Inc. Common Stock
SRRA
$542K 0.01%
7,928
-2,500
-24% -$171K
BLRX
114
BioLineRX
BLRX
$15.5M
$447K 0.01%
1,731
– –
SCTL
115
DELISTED
Societal CDMO, Inc. Common Stock
SCTL
$255K ﹤0.01%
48,501
-71,202
-59% -$374K
XYLO
116
DELISTED
Xylo Technologies
XYLO
$44K ﹤0.01%
375
– –
ACIU icon
117
AC Immune
ACIU
$227M
– –
-1,440,000
Closed -$13.6M
AFMD
118
DELISTED
Affimed
AFMD
– –
-32,665
Closed -$1.02M
ALLK
119
DELISTED
Allakos
ALLK
– –
-175,000
Closed -$9.15M
BLUE
120
DELISTED
bluebird bio
BLUE
– –
-29,892
Closed -$38.4M
CNC icon
121
Centene
CNC
$14.8B
– –
-834,800
Closed -$48.1M
CVS icon
122
CVS Health
CVS
$93B
– –
-793,800
Closed -$52M
DVA icon
123
DaVita
DVA
$9.72B
– –
-534,000
Closed -$27.5M
WVE icon
124
Wave Life Sciences
WVE
$1.27B
– –
0
– –
YI
125
111 Inc
YI
$52M
– –
-50,000
Closed -$3.07M
2 3 4
5
6