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OrbiMed Portfolio holdings

AUM $5.4B
1-Year Est. Return 163.13%
This Fund
S&P 500
This Quarter Est. Return
-0.47%
1 Year Est. Return
+163.13%
3 Year Est. Return
+393.16%
5 Year Est. Return
+486.34%
10 Year Est. Return
+3,312.73%
AUM
$5.52B
AUM Growth
-$648M
Cap. Flow
+$87.1M
Cap. Flow %
1.58%
Top 10 Hldgs %
32.16%
Holding
158
New
15
Increased
26
Reduced
36
Closed
15

Top Buys

Rank Stock Value
1
SVA
Sinovac Biotech, Ltd
SVA
+$349M
2
PGNY icon
Progyny
PGNY
+$22.4M
3
XENE icon
Xenon Pharmaceuticals
XENE
+$19.5M
4
TVTX icon
Travere Therapeutics
TVTX
+$19.4M
5
IONS icon
Ionis Pharmaceuticals
IONS
+$17.1M

Top Sells

Rank Stock Value
1
DXCM icon
DexCom
DXCM
+$76.7M
2
PFE icon
Pfizer
PFE
+$59.2M
3
IOVA icon
Iovance Biotherapeutics
IOVA
+$50.3M
4
NSTG
NanoString Technologies, Inc.
NSTG
+$40.2M
5
MRTX
Mirati Therapeutics, Inc. Common Stock
MRTX
+$34.3M

Sector Composition

Rank Sector Weight
1 Healthcare 97.72%
2 Miscellaneous 2.28%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
KDNY
51
DELISTED
Chinook Therapeutics, Inc. Common Stock
KDNY
$33.2M 0.6%
1,896,300
+478,000
+34% +$7.5M
PCVX icon
52
Vaxcyte
PCVX
$8.78B
$32.9M 0.6%
1,513,659
– –
ACRS icon
53
Aclaris Therapeutics
ACRS
$815M
$32.5M 0.59%
2,325,500
+745,600
+47% +$10.4M
IOVA icon
54
Iovance Biotherapeutics
IOVA
$4.19B
$30.9M 0.56%
2,798,441
-3,834,565
-58% -$50.3M
VRNA
55
DELISTED
Verona Pharma
VRNA
$23.9M 0.43%
5,694,841
– –
SCPH
56
DELISTED
scPharmaceuticals
SCPH
$23.1M 0.42%
4,797,148
– –
BIIB icon
57
Biogen
BIIB
$32B
$22.8M 0.41%
111,600
-6,300
-5% -$1.29M
TELA icon
58
TELA Bio
TELA
$47.1M
$21.2M 0.38%
3,027,542
– –
PASG icon
59
Passage Bio
PASG
$15.5M
$21.1M 0.38%
446,600
+80,000
+22% +$3.74M
DBTX
60
DELISTED
Decibel Therapeutics, Inc. Common Stock
DBTX
$20.8M 0.38%
4,945,192
– –
NPCE icon
61
Neuropace
NPCE
$489M
$19.9M 0.36%
4,012,281
– –
RXST icon
62
RxSight
RXST
$236M
$19.5M 0.35%
1,383,500
– –
MGTX icon
63
MeiraGTx Holdings
MGTX
$1.21B
$18.9M 0.34%
2,501,618
-795,048
-24% -$7.71M
TVTX icon
64
Travere Therapeutics
TVTX
$5.8B
$18.7M 0.34%
+772,200
New +$19.4M
PGNY icon
65
Progyny
PGNY
$2.14B
$18.2M 0.33%
+625,000
New +$22.4M
GILD icon
66
Gilead Sciences
GILD
$181B
$17.8M 0.32%
287,600
– –
ALXO icon
67
ALX Oncology
ALXO
$263M
$17.7M 0.32%
2,186,269
+1,564,569
+252% +$17M
IONS icon
68
Ionis Pharmaceuticals
IONS
$7.89B
$16.8M 0.3%
+453,400
New +$17.1M
IVVD icon
69
Invivyd
IVVD
$248M
$16.6M 0.3%
5,056,000
– –
QURE icon
70
uniQure
QURE
$3.01B
$16.3M 0.3%
874,849
-44,400
-5% -$706K
GHRS icon
71
GH Research
GHRS
$1.87B
$16.2M 0.29%
1,622,060
+193,328
+14% +$2.51M
RAPT
72
DELISTED
RAPT Therapeutics
RAPT
$15.8M 0.29%
108,300
+63,137
+140% +$8.41M
VTYX
73
DELISTED
Ventyx Biosciences
VTYX
$15.8M 0.29%
1,289,280
– –
AMGN icon
74
Amgen
AMGN
$205B
$13.9M 0.25%
57,100
– –
BLU
75
DELISTED
BELLUS Health Inc.
BLU
$13.4M 0.24%
1,454,800
– –
1 2
3
4 5

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OrbiMed's Q2 2022 Portfolio in Review

As of Q2 2022, OrbiMed held 158 positions worth $5.52B, down 11% from $6.17B the previous quarter. Its ten largest holdings account for 32% of the portfolio.

OrbiMed's Q2 2022 filing shows 15 new, 26 increased, 36 reduced and 15 closed positions. Its largest new stake was Sinovac Biotech, Ltd: 2,718,735 shares worth $350M. The largest sale was DexCom, an estimated $76.7M.

By sector, the portfolio is most concentrated in Healthcare at 98% of assets, down from 98% a quarter earlier, followed by Miscellaneous.

  • OrbiMed's largest Q2 2022 buy was Sinovac Biotech, Ltd: 2,718,735 shares worth $350M.
  • OrbiMed added most to Xenon Pharmaceuticals in Q2 2022, an estimated $19.5M increase.
  • OrbiMed's biggest Q2 2022 reduction was Pfizer, cutting an estimated $59.2M.
  • OrbiMed fully exited DexCom in Q2 2022, selling an estimated $76.7M.
  • OrbiMed's ten largest holdings make up 32% of its $5.52B portfolio in Q2 2022.
  • OrbiMed opened 15 new positions and closed 15 in Q2 2022.
  • OrbiMed's portfolio value fell 11% quarter-over-quarter to $5.52B.

Based on OrbiMed's 13F filing for Q2 2022, filed 15 Aug 2022.