Janus Henderson Group
VRTX icon

Janus Henderson Group’s Vertex Pharmaceuticals VRTX Stock Holding History

Janus Henderson Group’s Portfolio VRTX Stock Details VRTX Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		$952M Sell
2,131,527
-90,426
-4% -$42.2M 0.45% 41
2025
Q4 		$1.01B Buy
2,221,953
+102,846
+5% +$44.3M 0.45% 41
2025
Q3 		$830M Sell
2,119,107
-500,427
-19% -$209M 0.38% 50
2025
Q2 		$1.17B Sell
2,619,534
-128,403
-5% -$59.2M 0.57% 30
2025
Q1 		$1.35B Sell
2,747,937
-85,952
-3% -$40.1M 0.74% 16
2024
Q4 		$1.14B Buy
2,833,889
+317,058
+13% +$147M 0.58% 26
2024
Q3 		$1.17B Buy
2,516,831
+100,114
+4% +$48.1M 0.6% 26
2024
Q2 		$1.13B Sell
2,416,717
-167,598
-6% -$72.7M 0.61% 24
2024
Q1 		$1.08B Buy
2,584,315
+244,336
+10% +$103M 0.59% 30
2023
Q4 		$952M Buy
2,339,979
+681,156
+41% +$252M 0.57% 31
2023
Q3 		$577M Buy
1,658,823
+223,905
+16% +$78.3M 0.38% 62
2023
Q2 		$505M Buy
1,434,918
+68,206
+5% +$23M 0.31% 84
2023
Q1 		$431M Sell
1,366,712
-18,764
-1% -$5.63M 0.28% 89
2022
Q4 		$400M Sell
1,385,476
-1,617,594
-54% -$493M 0.29% 91
2022
Q3 		$870M Buy
3,003,070
+1,364,118
+83% +$392M 0.33% 72
2022
Q2 		$462M Sell
1,638,952
-166,647
-9% -$44.6M 0.32% 80
2022
Q1 		$471M Sell
1,805,599
-185,141
-9% -$43.9M 0.23% 106
2021
Q4 		$437M Sell
1,990,740
-144,038
-7% -$28M 0.18% 134
2021
Q3 		$387M Sell
2,134,778
-2,153,680
-50% -$420M 0.17% 138
2021
Q2 		$865M Sell
4,288,458
-220,351
-5% -$46.1M 0.37% 59
2021
Q1 		$969M Buy
4,508,809
+342,275
+8% +$75.2M 0.44% 47
2020
Q4 		$985M Buy
4,166,534
+2,265,577
+119% +$520M 0.46% 43
2020
Q3 		$517M Sell
1,900,957
-62,356
-3% -$17.2M 0.27% 83
2020
Q2 		$570M Buy
1,963,313
+91,678
+5% +$24.9M 0.32% 67
2020
Q1 		$445M Sell
1,871,635
-263,221
-12% -$60.4M 0.31% 70
2019
Q4 		$467M Buy
2,134,856
+262,589
+14% +$53.1M 0.24% 99
2019
Q3 		$317M Buy
1,872,267
+822,331
+78% +$145M 0.17% 143
2019
Q2 		$193M Buy
1,049,936
+283,447
+37% +$49.6M 0.1% 226
2019
Q1 		$141M Sell
766,489
-114,085
-13% -$21.1M 0.08% 296
2018
Q4 		$146M Buy
880,574
+366,207
+71% +$63.5M 0.09% 268
2018
Q3 		$99.1M Sell
514,367
-300,420
-37% -$53.5M 0.05% 398
2018
Q2 		$138M Sell
814,787
-37,454
-4% -$5.81M 0.08% 301
2018
Q1 		$139M Sell
852,241
-319,130
-27% -$52.1M 0.08% 286
2017
Q4 		$176M Buy
1,171,371
+579,501
+98% +$85.8M 0.11% 228
2017
Q3 		$90M Buy
591,870
+142,895
+32% +$21.5M 0.06% 386
2017
Q2 		$57.9M Buy
448,975
+414,206
+1,191% +$49.9M 0.04% 484
2017
Q1 		$3.8M Hold
34,769
– – 0.03% 399
2016
Q4 		$2.56M Buy
34,769
+3,706
+12% +$302K 0.02% 454
2016
Q3 		$2.71M Hold
31,063
– – 0.02% 430
2016
Q2 		$2.67M Hold
31,063
– – 0.02% 420
2016
Q1 		$2.47M Hold
31,063
– – 0.02% 447
2015
Q4 		$3.91M Sell
31,063
-119,254
-79% -$14.4M 0.03% 379
2015
Q3 		$15.6M Hold
150,317
– – 0.14% 184
2015
Q2 		$18.6M Sell
150,317
-1,755
-1% -$221K 0.15% 178
2015
Q1 		$17.9M Buy
152,072
+119,254
+363% +$14.3M 0.14% 202
2014
Q4 		$3.9M Buy
32,818
+844
+3% +$95.1K 0.03% 401
2014
Q3 		$3.59M Hold
31,974
– – 0.03% 329
2014
Q2 		$3.03M Hold
31,974
– – 0.03% 351
2014
Q1 		$2.26M Buy
31,974
+4,900
+18% +$388K 0.02% 410
2013
Q4 		$2.01M Hold
27,074
– – 0.02% 394
2013
Q3 		$2.05M Hold
27,074
– – 0.02% 388
2013
Q2 		$2.18M Buy
+27,074
New +$1.99M 0.03% 368

Other funds holding VRTX

Capital World Investors
Capital World Investors Los Angeles, California $733B AUM 35.63% 1-Year Est. Return
BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
Capital Research Global Investors
Capital Research Global Investors Los Angeles, California $645B AUM 30.41% 1-Year Est. Return
VCM
Vanguard Capital Management Malvern, Pennsylvania $4.04T AUM
State Street
State Street Boston, Massachusetts $2.9T AUM 29.55% 1-Year Est. Return
Invesco
Invesco Atlanta, Georgia $1.02T AUM 30.18% 1-Year Est. Return
JP Morgan Chase
JP Morgan Chase New York $1.56T AUM 27.86% 1-Year Est. Return
Geode Capital Management
Geode Capital Management Boston, Massachusetts $1.61T AUM 30.72% 1-Year Est. Return
VPM
Vanguard Portfolio Management Malvern, Pennsylvania $1.91T AUM
Capital International Investors
Capital International Investors Los Angeles, California $427B AUM 29.17% 1-Year Est. Return

Janus Henderson Group's VRTX Position: Q1 2026 in Review

Janus Henderson Group reduced its Vertex Pharmaceuticals (VRTX) stake by 4.1% in Q1 2026, selling an estimated $42.2M and leaving 2,131,527 shares worth $952M. The position accounts for 0.45% of the portfolio, ranked #41.

Janus Henderson Group first reported a position in VRTX in Q2 2013 and has held it in 52 quarters since. The position peaked at $1.35B in Q1 2025. 1,687 funds tracked by Wall St. Rank hold VRTX as of Q1 2026.

  • Janus Henderson Group held 2,131,527 shares of Vertex Pharmaceuticals worth $952M as of Q1 2026.
  • Janus Henderson Group sold 90,426 Vertex Pharmaceuticals shares in Q1 2026, an estimated $42.2M.
  • Vertex Pharmaceuticals made up 0.45% of Janus Henderson Group's portfolio in Q1 2026, its #41 holding.
  • Janus Henderson Group first reported a position in Vertex Pharmaceuticals in Q2 2013 and has held it in 52 quarters since.
  • Janus Henderson Group's Vertex Pharmaceuticals position peaked at $1.35B in Q1 2025.
  • 1,687 funds tracked by Wall St. Rank held Vertex Pharmaceuticals as of Q1 2026.

Based on Janus Henderson Group's 13F filing for Q1 2026, filed 15 May 2026.