Jane Street’s Vertex Pharmaceuticals VRTX Stock Holding History

Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake
Trade Value Portfolio Weight Portfolio Position
2026
Q1
$64.9M Buy
145,300
+32,200
+28% +$15M 0.01% 897
2025
Q4
$51.3M Buy
113,100
+59,500
+111% +$25.6M 0.01% 931
2025
Q3
$21M Sell
53,600
-12,600
-19% -$5.27M ﹤0.01% 1623
2025
Q2
$29.5M Buy
66,200
+21,300
+47% +$9.82M 0.01% 1103
2025
Q1
$21.8M Sell
44,900
-28,200
-39% -$13.1M 0.01% 1217
2024
Q4
$29.4M Buy
73,100
+43,300
+145% +$20.1M 0.01% 989
2024
Q3
$13.9M Sell
29,800
-27,100
-48% -$13M ﹤0.01% 1588
2024
Q2
$26.7M Sell
56,900
-15,600
-22% -$6.77M 0.01% 1072
2024
Q1
$30.3M Sell
72,500
-38,900
-35% -$16.4M 0.01% 903
2023
Q4
$45.3M Buy
111,400
+38,100
+52% +$14.1M 0.01% 728
2023
Q3
$25.5M Buy
73,300
+53,000
+261% +$18.5M 0.01% 915
2023
Q2
$7.14M Sell
20,300
-34,900
-63% -$11.8M ﹤0.01% 2286
2023
Q1
$17.4M Sell
55,200
-49,000
-47% -$14.7M 0.01% 1105
2022
Q4
$30.1M Sell
104,200
-36,500
-26% -$11.1M 0.01% 755
2022
Q3
$40.7M Sell
140,700
-20,800
-13% -$5.98M 0.02% 614
2022
Q2
$45.5M Sell
161,500
-58,000
-26% -$15.5M 0.02% 593
2022
Q1
$57.3M Sell
219,500
-29,100
-12% -$6.91M 0.02% 622
2021
Q4
$54.6M Buy
248,600
+8,700
+4% +$1.69M 0.02% 609
2021
Q3
$43.5M Hold
239,900
0.02% 663
2021
Q2
$48.4M Buy
239,900
+15,500
+7% +$3.24M 0.02% 564
2021
Q1
$48.2M Buy
224,400
+112,900
+101% +$24.8M 0.02% 489
2020
Q4
$26.4M Buy
111,500
+49,300
+79% +$11.3M 0.01% 712
2020
Q3
$16.9M Sell
62,200
-29,500
-32% -$8.14M 0.01% 864
2020
Q2
$26.6M Buy
91,700
+77,900
+564% +$21.1M 0.02% 614
2020
Q1
$3.28M Sell
13,800
-9,500
-41% -$2.18M ﹤0.01% 1545
2019
Q4
$5.1M Buy
23,300
+8,200
+54% +$1.66M 0.01% 1080
2019
Q3
$2.56M Sell
15,100
-300
-2% -$53.1K ﹤0.01% 1554
2019
Q2
$2.82M Sell
15,400
-3,800
-20% -$664K 0.01% 1537
2019
Q1
$3.53M Sell
19,200
-8,100
-30% -$1.5M 0.01% 1444
2018
Q4
$4.52M Buy
27,300
+18,200
+200% +$3.15M 0.01% 1010
2018
Q3
$1.75M Buy
9,100
+1,600
+21% +$285K ﹤0.01% 2051
2018
Q2
$1.27M Hold
7,500
﹤0.01% 2445
2018
Q1
$1.22M Buy
7,500
+5,600
+295% +$915K ﹤0.01% 2409
2017
Q4
$285K Sell
1,900
-26,900
-93% -$3.98M ﹤0.01% 3822
2017
Q3
$4.38M Buy
28,800
+9,400
+48% +$1.41M 0.01% 960
2017
Q2
$2.5M Sell
19,400
-61,700
-76% -$7.43M 0.01% 1287
2017
Q1
$8.87M Buy
81,100
+77,600
+2,217% +$6.83M 0.04% 426
2016
Q4
$258K Sell
3,500
-300
-8% -$24.4K ﹤0.01% 3504
2016
Q3
$331K Buy
+3,800
New +$359K ﹤0.01% 3205

Other funds holding VRTX

Jane Street's VRTX Position: Q1 2026 in Review

Jane Street increased its Vertex Pharmaceuticals (VRTX) stake by 993% in Q1 2026, buying an estimated $52.1M and bringing the position to 122,946 shares worth $54.9M. The position accounts for 0.01% of the portfolio, ranked #990.

Jane Street first reported a position in VRTX in Q2 2013 and has held it in 49 quarters since. The position peaked at $142M in Q2 2024. 1,687 funds tracked by Wall St. Rank hold VRTX as of Q1 2026.

  • Jane Street held 122,946 shares of Vertex Pharmaceuticals worth $54.9M as of Q1 2026.
  • Jane Street bought 111,700 Vertex Pharmaceuticals shares in Q1 2026, an estimated $52.1M.
  • Vertex Pharmaceuticals made up 0.01% of Jane Street's portfolio in Q1 2026, its #990 holding.
  • Jane Street first reported a position in Vertex Pharmaceuticals in Q2 2013 and has held it in 49 quarters since.
  • Jane Street's Vertex Pharmaceuticals position peaked at $142M in Q2 2024.
  • 1,687 funds tracked by Wall St. Rank held Vertex Pharmaceuticals as of Q1 2026.

Based on Jane Street's 13F filing for Q1 2026, filed 12 May 2026.