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HHMI

Howard Hughes Medical Institute Portfolio holdings

AUM $445M
1-Year Est. Return 42.75%
This Fund
S&P 500
This Quarter Est. Return
-7.04%
1 Year Est. Return
+42.75%
3 Year Est. Return
+70.92%
5 Year Est. Return
+91.54%
10 Year Est. Return
+350.22%
AUM
$416M
AUM Growth
+$241M
Cap. Flow
+$269M
Cap. Flow %
64.6%
Top 10 Hldgs %
83.32%
Holding
503
New
3
Increased
27
Reduced
1
Closed
472

Top Buys

Rank Stock Value
1
NVDA icon
NVIDIA
NVDA
+$58.1M
2
AAPL icon
Apple
AAPL
+$50.9M
3
GOOGL icon
Alphabet (Google) Class A
GOOGL
+$44.7M
4
MSFT icon
Microsoft
MSFT
+$42.1M
5
AMZN icon
Amazon
AMZN
+$28.8M

Top Sells

Rank Stock Value
1
SPY icon
State Street SPDR S&P 500 ETF Trust
SPY
+$102M
2
GOOG icon
Alphabet (Google) Class C
GOOG
+$314K
3
BRK.B icon
Berkshire Hathaway Class B
BRK.B
+$199K
4
JPM icon
JPMorgan Chase
JPM
+$189K
5
LLY icon
Eli Lilly
LLY
+$184K

Sector Composition

Rank Sector Weight
1 Technology 59.32%
2 Communication Services 16.1%
3 Consumer Discretionary 10.79%
4 Financials 0%
5 Healthcare 0%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
SPY icon
1
State Street SPDR S&P 500 ETF Trust
SPY
$813B
$57.4M 13.79%
88,185
-149,700
-63% -$102M
NVDA icon
2
NVIDIA
NVDA
$5.45T
$56.2M 13.51%
322,105
+316,884
+6,069% +$58.1M
AAPL icon
3
Apple
AAPL
$4.46T
$50.4M 12.13%
198,755
+195,571
+6,142% +$50.9M
GOOGL icon
4
Alphabet (Google) Class A
GOOGL
$4.23T
$41.3M 9.94%
143,665
+142,415
+11,393% +$44.7M
MSFT icon
5
Microsoft
MSFT
$3.68T
$37.9M 9.11%
102,314
+100,714
+6,295% +$42.1M
AMZN icon
6
Amazon
AMZN
$2.83T
$27.7M 6.66%
132,871
+130,778
+6,248% +$28.8M
TSM icon
7
TSMC
TSM
$2.21T
$22.6M 5.43%
+66,773
New +$23M
AVGO icon
8
Broadcom
AVGO
$1.87T
$20.1M 4.84%
65,028
+64,012
+6,300% +$21.1M
META icon
9
Meta Platforms (Facebook)
META
$1.5T
$17.6M 4.24%
30,787
+30,318
+6,464% +$19.4M
TSLA icon
10
Tesla
TSLA
$1.35T
$15.3M 3.68%
41,177
+40,574
+6,729% +$16.7M
ASML icon
11
ASML
ASML
$708B
$7.14M 1.72%
+5,405
New +$7.41M
NFLX icon
12
Netflix
NFLX
$325B
$5.64M 1.36%
58,670
+57,757
+6,326% +$5.09M
MU icon
13
Micron Technology
MU
$1.1T
$5.31M 1.28%
15,704
+15,463
+6,416% +$6.06M
AMD icon
14
Advanced Micro Devices
AMD
$840B
$4.6M 1.11%
22,624
+22,274
+6,364% +$4.76M
PLTR icon
15
Palantir
PLTR
$418B
$4.5M 1.08%
30,757
+30,267
+6,177% +$4.63M
CSCO icon
16
Cisco
CSCO
$440B
$3.9M 0.94%
50,326
+49,476
+5,821% +$3.87M
AMAT icon
17
Applied Materials
AMAT
$403B
$3.75M 0.9%
10,984
+10,812
+6,286% +$3.64M
LRCX icon
18
Lam Research
LRCX
$416B
$3.72M 0.89%
17,396
+17,126
+6,343% +$3.83M
ORCL icon
19
Oracle
ORCL
$434B
$3.51M 0.84%
23,851
+23,491
+6,525% +$3.82M
IBM icon
20
IBM
IBM
$221B
$3.16M 0.76%
13,023
+12,822
+6,379% +$3.47M
KLAC icon
21
KLA
KLAC
$266B
$2.69M 0.65%
18,250
+17,970
+6,418% +$2.63M
SAP icon
22
SAP
SAP
$240B
$2.55M 0.61%
+14,868
New +$3.07M
INTC icon
23
Intel
INTC
$517B
$2.52M 0.61%
57,142
+56,177
+5,821% +$2.57M
TXN icon
24
Texas Instruments
TXN
$255B
$2.45M 0.59%
12,645
+12,449
+6,352% +$2.52M
DIS icon
25
Walt Disney
DIS
$184B
$2.38M 0.57%
24,660
+24,275
+6,305% +$2.57M
1
2 3 4 5

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Howard Hughes Medical Institute's Q1 2026 Portfolio in Review

As of Q1 2026, Howard Hughes Medical Institute held 503 positions worth $416M, up 138% from $175M the previous quarter. Its ten largest holdings account for 83% of the portfolio.

Howard Hughes Medical Institute deployed $269M of net new capital in Q1 2026, opening 3 new positions and adding to 27 existing holdings. Its largest new stake was TSMC: 66,773 shares worth $22.6M.

By sector, the portfolio is most concentrated in Technology at 59% of assets, up from 2.5% a quarter earlier, followed by Communication Services and Consumer Discretionary.

On the sell side, the largest reduction was State Street SPDR S&P 500 ETF Trust, an estimated $102M trimmed.

  • Howard Hughes Medical Institute's largest Q1 2026 buy was TSMC: 66,773 shares worth $22.6M.
  • Howard Hughes Medical Institute added most to NVIDIA in Q1 2026, an estimated $58.1M increase.
  • Howard Hughes Medical Institute's biggest Q1 2026 reduction was State Street SPDR S&P 500 ETF Trust, cutting an estimated $102M.
  • Howard Hughes Medical Institute fully exited Alphabet (Google) Class C in Q1 2026, selling an estimated $314K.
  • Howard Hughes Medical Institute's ten largest holdings make up 83% of its $416M portfolio in Q1 2026.
  • Howard Hughes Medical Institute opened 3 new positions and closed 472 in Q1 2026.
  • Howard Hughes Medical Institute's portfolio value rose 138% quarter-over-quarter to $416M.

Based on Howard Hughes Medical Institute's 13F filing for Q1 2026, filed 15 May 2026.