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HHMI

Howard Hughes Medical Institute Portfolio holdings

AUM $416M
1-Year Est. Return 13.82%
This Fund
S&P 500
This Quarter Est. Return
-7.04%
1 Year Est. Return
+13.82%
3 Year Est. Return
+59.34%
5 Year Est. Return
+48.21%
10 Year Est. Return
+227.75%
AUM
$416M
AUM Growth
+$241M
Cap. Flow
+$269M
Cap. Flow %
64.6%
Top 10 Hldgs %
83.32%
Holding
503
New
3
Increased
27
Reduced
1
Closed
472

Top Buys

Rank Stock Value
1
NVDA icon
NVIDIA
NVDA
+$58.1M
2
AAPL icon
Apple
AAPL
+$50.9M
3
GOOGL icon
Alphabet (Google) Class A
GOOGL
+$44.7M
4
MSFT icon
Microsoft
MSFT
+$42.1M
5
AMZN icon
Amazon
AMZN
+$28.8M

Top Sells

Rank Stock Value
1
SPY icon
State Street SPDR S&P 500 ETF Trust
SPY
+$102M
2
GOOG icon
Alphabet (Google) Class C
GOOG
+$314K
3
BRK.B icon
Berkshire Hathaway Class B
BRK.B
+$199K
4
JPM icon
JPMorgan Chase
JPM
+$189K
5
LLY icon
Eli Lilly
LLY
+$184K

Sector Composition

Rank Sector Weight
1 Technology 59.32%
2 Communication Services 16.1%
3 Consumer Discretionary 10.79%
4 Financials 0%
5 Healthcare 0%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
ODFL icon
351
Old Dominion Freight Line
ODFL
$44.1B
– –
-40
Closed -$6.27K
OKE icon
352
Oneok
OKE
$57.2B
– –
-135
Closed -$9.92K
OMC icon
353
Omnicom Group
OMC
$21.6B
– –
-69
Closed -$5.57K
ON icon
354
ON Semiconductor
ON
$31.8B
– –
-87
Closed -$4.71K
ORLY icon
355
O'Reilly Automotive
ORLY
$72.9B
– –
-183
Closed -$16.7K
OTIS icon
356
Otis Worldwide
OTIS
$27.4B
– –
-84
Closed -$7.34K
OXY icon
357
Occidental Petroleum
OXY
$56.8B
– –
-155
Closed -$6.37K
PANW icon
358
Palo Alto Networks
PANW
$270B
– –
-147
Closed -$27.1K
PAYC icon
359
Paycom
PAYC
$7.64B
– –
-10
Closed -$1.59K
PAYX icon
360
Paychex
PAYX
$41.6B
– –
-69
Closed -$7.74K
PCAR icon
361
PACCAR
PCAR
$69.8B
– –
-113
Closed -$12.4K
PCG icon
362
PG&E
PCG
$38.3B
– –
-474
Closed -$7.62K
PEG icon
363
Public Service Enterprise Group
PEG
$38.2B
– –
-107
Closed -$8.59K
PEP icon
364
PepsiCo
PEP
$190B
– –
-295
Closed -$42.3K
PFE icon
365
Pfizer
PFE
$143B
– –
-1,226
Closed -$30.5K
PFG icon
366
Principal Financial Group
PFG
$24.3B
– –
-44
Closed -$3.88K
PG icon
367
Procter & Gamble
PG
$336B
– –
-504
Closed -$72.2K
PGR icon
368
Progressive
PGR
$123B
– –
-126
Closed -$28.7K
PH icon
369
Parker-Hannifin
PH
$123B
– –
-27
Closed -$23.7K
PHM icon
370
Pultegroup
PHM
$24.1B
– –
-42
Closed -$4.92K
PKG icon
371
Packaging Corp of America
PKG
$21.9B
– –
-19
Closed -$3.92K
PLD icon
372
Prologis
PLD
$135B
– –
-200
Closed -$25.5K
PNC icon
373
PNC Financial Services
PNC
$99.7B
– –
-85
Closed -$17.7K
PNR icon
374
Pentair
PNR
$10.4B
– –
-35
Closed -$3.65K
PNW icon
375
Pinnacle West Capital
PNW
$12.2B
– –
-25
Closed -$2.22K
13 14
15
16 17

Similar funds

VM
Venator Management Pittsburgh, Pennsylvania $416M AUM 16.01% 1-Year Est. Return
SCP
Stevens Capital Partners Omaha, Nebraska $416M AUM 18.93% 1-Year Est. Return
SSC
Spruce Street Capital New York $416M AUM
SSC
Syverson Strege & Co West Des Moines, Iowa $416M AUM 21.16% 1-Year Est. Return
CEI
Clark Estates Inc New York $416M AUM 6.04% 1-Year Est. Return
I
InceptionR Lafayette, California $415M AUM 17.85% 1-Year Est. Return
AWCI
Alpine Woods Capital Investors Purchase, New York $417M AUM 26.83% 1-Year Est. Return
SCMS
Serenity Capital Management (Singapore) Singapore $414M AUM 16.41% 1-Year Est. Return

Howard Hughes Medical Institute's Q1 2026 Portfolio in Review

As of Q1 2026, Howard Hughes Medical Institute held 503 positions worth $416M, up 138% from $175M the previous quarter. Its ten largest holdings account for 83% of the portfolio.

Howard Hughes Medical Institute deployed $269M of net new capital in Q1 2026, opening 3 new positions and adding to 27 existing holdings. Its largest new stake was TSMC: 66,773 shares worth $22.6M.

By sector, the portfolio is most concentrated in Technology at 59% of assets, up from 2.5% a quarter earlier, followed by Communication Services and Consumer Discretionary.

On the sell side, the largest reduction was State Street SPDR S&P 500 ETF Trust, an estimated $102M trimmed.

  • Howard Hughes Medical Institute's largest Q1 2026 buy was TSMC: 66,773 shares worth $22.6M.
  • Howard Hughes Medical Institute added most to NVIDIA in Q1 2026, an estimated $58.1M increase.
  • Howard Hughes Medical Institute's biggest Q1 2026 reduction was State Street SPDR S&P 500 ETF Trust, cutting an estimated $102M.
  • Howard Hughes Medical Institute fully exited Alphabet (Google) Class C in Q1 2026, selling an estimated $314K.
  • Howard Hughes Medical Institute's ten largest holdings make up 83% of its $416M portfolio in Q1 2026.
  • Howard Hughes Medical Institute opened 3 new positions and closed 472 in Q1 2026.
  • Howard Hughes Medical Institute's portfolio value rose 138% quarter-over-quarter to $416M.

Based on Howard Hughes Medical Institute's 13F filing for Q1 2026, filed 15 May 2026.