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HHMI

Howard Hughes Medical Institute Portfolio holdings

AUM $416M
1-Year Est. Return 13.82%
This Fund
S&P 500
This Quarter Est. Return
-7.04%
1 Year Est. Return
+13.82%
3 Year Est. Return
+59.34%
5 Year Est. Return
+48.21%
10 Year Est. Return
+227.75%
AUM
$416M
AUM Growth
+$241M
Cap. Flow
+$269M
Cap. Flow %
64.6%
Top 10 Hldgs %
83.32%
Holding
503
New
3
Increased
27
Reduced
1
Closed
472

Top Buys

Rank Stock Value
1
NVDA icon
NVIDIA
NVDA
+$58.1M
2
AAPL icon
Apple
AAPL
+$50.9M
3
GOOGL icon
Alphabet (Google) Class A
GOOGL
+$44.7M
4
MSFT icon
Microsoft
MSFT
+$42.1M
5
AMZN icon
Amazon
AMZN
+$28.8M

Top Sells

Rank Stock Value
1
SPY icon
State Street SPDR S&P 500 ETF Trust
SPY
+$102M
2
GOOG icon
Alphabet (Google) Class C
GOOG
+$314K
3
BRK.B icon
Berkshire Hathaway Class B
BRK.B
+$199K
4
JPM icon
JPMorgan Chase
JPM
+$189K
5
LLY icon
Eli Lilly
LLY
+$184K

Sector Composition

Rank Sector Weight
1 Technology 59.32%
2 Communication Services 16.1%
3 Consumer Discretionary 10.79%
4 Financials 0%
5 Healthcare 0%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
MRNA icon
326
Moderna
MRNA
$21.8B
– –
-75
Closed -$2.21K
MS icon
327
Morgan Stanley
MS
$331B
– –
-261
Closed -$46.3K
MSCI icon
328
MSCI
MSCI
$41.6B
– –
-16
Closed -$9.18K
MSI icon
329
Motorola Solutions
MSI
$72.3B
– –
-36
Closed -$13.8K
MTCH icon
330
Match Group
MTCH
$9.19B
– –
-51
Closed -$1.65K
MTD icon
331
Mettler-Toledo International
MTD
$28.6B
– –
-4
Closed -$5.58K
MTB icon
332
M&T Bank
MTB
$35.7B
– –
-34
Closed -$6.85K
NCLH icon
333
Norwegian Cruise Line
NCLH
$8.51B
– –
-98
Closed -$2.19K
NDAQ icon
334
Nasdaq
NDAQ
$52.7B
– –
-97
Closed -$9.42K
NDSN icon
335
Nordson
NDSN
$16.6B
– –
-11
Closed -$2.65K
NEE icon
336
NextEra Energy
NEE
$181B
– –
-449
Closed -$36K
NEM icon
337
Newmont
NEM
$98.7B
– –
-235
Closed -$23.5K
NI icon
338
NiSource
NI
$21.3B
– –
-103
Closed -$4.3K
NKE icon
339
Nike
NKE
$61.9B
– –
-255
Closed -$16.2K
NOC icon
340
Northrop Grumman
NOC
$77.1B
– –
-29
Closed -$16.5K
NOW icon
341
ServiceNow
NOW
$115B
– –
-222
Closed -$34K
NRG icon
342
NRG Energy
NRG
$28.3B
– –
-42
Closed -$6.69K
NSC icon
343
Norfolk Southern
NSC
$75.4B
– –
-48
Closed -$13.9K
NTAP icon
344
NetApp
NTAP
$35B
– –
-43
Closed -$4.61K
NTRS icon
345
Northern Trust
NTRS
$33.3B
– –
-41
Closed -$5.6K
NUE icon
346
Nucor
NUE
$58.6B
– –
-50
Closed -$8.16K
NWS icon
347
News Corp Class B
NWS
$16.9B
– –
-26
Closed -$770
NWSA icon
348
News Corp Class A
NWSA
$14.9B
– –
-81
Closed -$2.12K
NXPI icon
349
NXP Semiconductors
NXPI
$57.8B
– –
-54
Closed -$11.7K
O icon
350
Realty Income
O
$59.6B
– –
-198
Closed -$11.2K
12 13
14
15 16

Similar funds

VM
Venator Management Pittsburgh, Pennsylvania $416M AUM 16.01% 1-Year Est. Return
SCP
Stevens Capital Partners Omaha, Nebraska $416M AUM 18.93% 1-Year Est. Return
SSC
Spruce Street Capital New York $416M AUM
SSC
Syverson Strege & Co West Des Moines, Iowa $416M AUM 21.16% 1-Year Est. Return
CEI
Clark Estates Inc New York $416M AUM 6.04% 1-Year Est. Return
I
InceptionR Lafayette, California $415M AUM 17.85% 1-Year Est. Return
AWCI
Alpine Woods Capital Investors Purchase, New York $417M AUM 26.83% 1-Year Est. Return
SCMS
Serenity Capital Management (Singapore) Singapore $414M AUM 16.41% 1-Year Est. Return

Howard Hughes Medical Institute's Q1 2026 Portfolio in Review

As of Q1 2026, Howard Hughes Medical Institute held 503 positions worth $416M, up 138% from $175M the previous quarter. Its ten largest holdings account for 83% of the portfolio.

Howard Hughes Medical Institute deployed $269M of net new capital in Q1 2026, opening 3 new positions and adding to 27 existing holdings. Its largest new stake was TSMC: 66,773 shares worth $22.6M.

By sector, the portfolio is most concentrated in Technology at 59% of assets, up from 2.5% a quarter earlier, followed by Communication Services and Consumer Discretionary.

On the sell side, the largest reduction was State Street SPDR S&P 500 ETF Trust, an estimated $102M trimmed.

  • Howard Hughes Medical Institute's largest Q1 2026 buy was TSMC: 66,773 shares worth $22.6M.
  • Howard Hughes Medical Institute added most to NVIDIA in Q1 2026, an estimated $58.1M increase.
  • Howard Hughes Medical Institute's biggest Q1 2026 reduction was State Street SPDR S&P 500 ETF Trust, cutting an estimated $102M.
  • Howard Hughes Medical Institute fully exited Alphabet (Google) Class C in Q1 2026, selling an estimated $314K.
  • Howard Hughes Medical Institute's ten largest holdings make up 83% of its $416M portfolio in Q1 2026.
  • Howard Hughes Medical Institute opened 3 new positions and closed 472 in Q1 2026.
  • Howard Hughes Medical Institute's portfolio value rose 138% quarter-over-quarter to $416M.

Based on Howard Hughes Medical Institute's 13F filing for Q1 2026, filed 15 May 2026.