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HHMI

Howard Hughes Medical Institute Portfolio holdings

AUM $416M
1-Year Est. Return 13.82%
This Fund
S&P 500
This Quarter Est. Return
-7.04%
1 Year Est. Return
+13.82%
3 Year Est. Return
+59.34%
5 Year Est. Return
+48.21%
10 Year Est. Return
+227.75%
AUM
$416M
AUM Growth
+$241M
Cap. Flow
+$269M
Cap. Flow %
64.6%
Top 10 Hldgs %
83.32%
Holding
503
New
3
Increased
27
Reduced
1
Closed
472

Top Buys

Rank Stock Value
1
NVDA icon
NVIDIA
NVDA
+$58.1M
2
AAPL icon
Apple
AAPL
+$50.9M
3
GOOGL icon
Alphabet (Google) Class A
GOOGL
+$44.7M
4
MSFT icon
Microsoft
MSFT
+$42.1M
5
AMZN icon
Amazon
AMZN
+$28.8M

Top Sells

Rank Stock Value
1
SPY icon
State Street SPDR S&P 500 ETF Trust
SPY
+$102M
2
GOOG icon
Alphabet (Google) Class C
GOOG
+$314K
3
BRK.B icon
Berkshire Hathaway Class B
BRK.B
+$199K
4
JPM icon
JPMorgan Chase
JPM
+$189K
5
LLY icon
Eli Lilly
LLY
+$184K

Sector Composition

Rank Sector Weight
1 Technology 59.32%
2 Communication Services 16.1%
3 Consumer Discretionary 10.79%
4 Financials 0%
5 Healthcare 0%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
KDP icon
276
Keurig Dr Pepper
KDP
$42.3B
– –
-292
Closed -$8.18K
KEY icon
277
KeyCorp
KEY
$24.2B
– –
-201
Closed -$4.15K
KEYS icon
278
Keysight
KEYS
$54.5B
– –
-37
Closed -$7.52K
KHC icon
279
Kraft Heinz
KHC
$30.7B
– –
-184
Closed -$4.46K
KIM icon
280
Kimco Realty
KIM
$17.2B
– –
-146
Closed -$2.96K
KKR icon
281
KKR & Co
KKR
$91.1B
– –
-147
Closed -$18.7K
KMB icon
282
Kimberly-Clark
KMB
$36.3B
– –
-71
Closed -$7.16K
KMI icon
283
Kinder Morgan
KMI
$71.7B
– –
-421
Closed -$11.6K
KO icon
284
Coca-Cola
KO
$377B
– –
-835
Closed -$58.4K
KR icon
285
Kroger
KR
$35.4B
– –
-131
Closed -$8.19K
KVUE icon
286
Kenvue
KVUE
$36.9B
– –
-413
Closed -$7.12K
L icon
287
Loews
L
$23.9B
– –
-37
Closed -$3.9K
LDOS icon
288
Leidos
LDOS
$14.5B
– –
-28
Closed -$5.05K
LEN icon
289
Lennar Class A
LEN
$19.8B
– –
-47
Closed -$4.83K
LH icon
290
Labcorp
LH
$25B
– –
-18
Closed -$4.52K
LHX icon
291
L3Harris
LHX
$51.6B
– –
-40
Closed -$11.7K
LII icon
292
Lennox International
LII
$14.4B
– –
-6
Closed -$2.91K
LIN icon
293
Linde
LIN
$221B
– –
-101
Closed -$43.1K
LLY icon
294
Eli Lilly
LLY
$1.02T
– –
-171
Closed -$184K
LMT icon
295
Lockheed Martin
LMT
$134B
– –
-44
Closed -$21.3K
LNT icon
296
Alliant Energy
LNT
$18.3B
– –
-55
Closed -$3.58K
LOW icon
297
Lowe's Companies
LOW
$117B
– –
-121
Closed -$29.2K
LULU icon
298
lululemon athletica
LULU
$13.5B
– –
-24
Closed -$4.99K
LUV icon
299
Southwest Airlines
LUV
$22B
– –
-111
Closed -$4.59K
LVS icon
300
Las Vegas Sands
LVS
$31.7B
– –
-66
Closed -$4.3K
10 11
12
13 14

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VM
Venator Management Pittsburgh, Pennsylvania $416M AUM 16.01% 1-Year Est. Return
SCP
Stevens Capital Partners Omaha, Nebraska $416M AUM 18.93% 1-Year Est. Return
SSC
Spruce Street Capital New York $416M AUM
SSC
Syverson Strege & Co West Des Moines, Iowa $416M AUM 21.16% 1-Year Est. Return
CEI
Clark Estates Inc New York $416M AUM 6.04% 1-Year Est. Return
I
InceptionR Lafayette, California $415M AUM 17.85% 1-Year Est. Return
AWCI
Alpine Woods Capital Investors Purchase, New York $417M AUM 26.83% 1-Year Est. Return
SCMS
Serenity Capital Management (Singapore) Singapore $414M AUM 16.41% 1-Year Est. Return

Howard Hughes Medical Institute's Q1 2026 Portfolio in Review

As of Q1 2026, Howard Hughes Medical Institute held 503 positions worth $416M, up 138% from $175M the previous quarter. Its ten largest holdings account for 83% of the portfolio.

Howard Hughes Medical Institute deployed $269M of net new capital in Q1 2026, opening 3 new positions and adding to 27 existing holdings. Its largest new stake was TSMC: 66,773 shares worth $22.6M.

By sector, the portfolio is most concentrated in Technology at 59% of assets, up from 2.5% a quarter earlier, followed by Communication Services and Consumer Discretionary.

On the sell side, the largest reduction was State Street SPDR S&P 500 ETF Trust, an estimated $102M trimmed.

  • Howard Hughes Medical Institute's largest Q1 2026 buy was TSMC: 66,773 shares worth $22.6M.
  • Howard Hughes Medical Institute added most to NVIDIA in Q1 2026, an estimated $58.1M increase.
  • Howard Hughes Medical Institute's biggest Q1 2026 reduction was State Street SPDR S&P 500 ETF Trust, cutting an estimated $102M.
  • Howard Hughes Medical Institute fully exited Alphabet (Google) Class C in Q1 2026, selling an estimated $314K.
  • Howard Hughes Medical Institute's ten largest holdings make up 83% of its $416M portfolio in Q1 2026.
  • Howard Hughes Medical Institute opened 3 new positions and closed 472 in Q1 2026.
  • Howard Hughes Medical Institute's portfolio value rose 138% quarter-over-quarter to $416M.

Based on Howard Hughes Medical Institute's 13F filing for Q1 2026, filed 15 May 2026.