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GTC

Ghost Tree Capital Portfolio holdings

AUM $331M
1-Year Est. Return 70.11%
This Fund
S&P 500
This Quarter Est. Return
+28.76%
1 Year Est. Return
+70.11%
3 Year Est. Return
+265.05%
5 Year Est. Return
+3,034.98%
10 Year Est. Return
+22,104.75%
AUM
$361M
AUM Growth
+$55.4M
Cap. Flow
+$121M
Cap. Flow %
33.42%
Top 10 Hldgs %
40.07%
Holding
85
New
33
Increased
24
Reduced
13
Closed
13

Sector Composition

Rank Sector Weight
1 Healthcare 86.09%
2 Miscellaneous 13.91%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake
Capital Flow
PHAT icon
26
Phathom Pharmaceuticals
PHAT
$769M
$5.15M 1.43%
485,000
+99,759
+26% +$847K
IMVT icon
27
CALL
Immunovant
IMVT
$8.11B
$4.85M 1.34%
+150,000
New +$5.47M
ACAD icon
28
Acadia Pharmaceuticals
ACAD
$4.83B
$4.16M 1.15%
225,000
+175,000
+350% +$4.34M
INSM icon
29
Insmed
INSM
$27.6B
$4.07M 1.13%
+150,000
New +$4.2M
TNYA icon
30
Tenaya Therapeutics
TNYA
$153M
$4.05M 1.12%
+775,000
New +$3.71M
IMVT icon
31
Immunovant
IMVT
$8.11B
$4.04M 1.12%
+125,000
New +$4.56M
SYRE icon
32
Spyre Therapeutics
SYRE
$7.85B
$3.79M 1.05%
+100,000
New +$2.9M
ACAD icon
33
CALL
Acadia Pharmaceuticals
ACAD
$4.83B
$3.7M 1.02%
+200,000
New +$4.96M
SNDX icon
34
Syndax Pharmaceuticals
SNDX
$1.84B
$3.57M 0.99%
+150,000
New +$3.35M
ITCI
35
CALL
DELISTED
Intra-Cellular Therapies Inc.
ITCI
$3.46M 0.96%
+50,000
New +$3.44M
ENGN icon
36
enGene Therapeutics
ENGN
$122M
$3.39M 0.94%
+200,000
New +$2.45M
CGON icon
37
CG Oncology
CGON
$6.62B
$3.29M 0.91%
+75,000
New +$3.06M
GPCR icon
38
Structure Therapeutics
GPCR
$3.38B
$3.21M 0.89%
75,000
-75,000
-50% -$3.16M
BBOT
39
BridgeBio Oncology
BBOT
$720M
$3.12M 0.86%
+300,000
New +$3.11M
COGT icon
40
Cogent Biosciences
COGT
$6.03B
$3.02M 0.84%
450,000
+255,000
+131% +$1.58M
AQST icon
41
Aquestive Therapeutics
AQST
$670M
$2.99M 0.83%
+702,941
New +$2.34M
DCPH
42
DELISTED
Deciphera Pharmaceuticals, Inc. Common Stock
DCPH
$2.78M 0.77%
176,513
-48,487
-22% -$746K
TSHA icon
43
Taysha Gene Therapies
TSHA
$1.82B
$2.73M 0.75%
950,000
-1,150,000
-55% -$2.4M
RAPT
44
CALL
DELISTED
RAPT Therapeutics
RAPT
$2.69M 0.75%
+37,500
New +$5.21M
GERN icon
45
Geron
GERN
$1.01B
$2.64M 0.73%
+800,000
New +$1.79M
MRNS
46
DELISTED
Marinus Pharmaceuticals, Inc
MRNS
$2.58M 0.71%
285,000
+150,000
+111% +$1.46M
ALT icon
47
Altimmune
ALT
$665M
$2.54M 0.7%
+250,000
New +$2.54M
RGNX icon
48
Regenxbio
RGNX
$590M
$2.53M 0.7%
+120,000
New +$2.14M
KRYS icon
49
Krystal Biotech
KRYS
$10.6B
$2.49M 0.69%
14,000
-36,000
-72% -$5M
KALV
50
DELISTED
KalVista Pharmaceuticals
KALV
$2.37M 0.66%
200,000
+69,964
+54% +$933K

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Ghost Tree Capital's Q1 2024 Portfolio in Review

As of Q1 2024, Ghost Tree Capital held 85 positions worth $361M, up 18% from $306M the previous quarter. Its ten largest holdings account for 40% of the portfolio.

Ghost Tree Capital deployed $121M of net new capital in Q1 2024, opening 33 new positions and adding to 24 existing holdings. Its largest new stake was Apellis Pharmaceuticals: 130,000 shares worth $7.64M.

By sector, the portfolio is most concentrated in Healthcare at 86% of assets, up from 57% a quarter earlier, followed by Miscellaneous.

On the sell side, the largest reduction was Krystal Biotech, an estimated $5M trimmed.

  • Ghost Tree Capital's largest Q1 2024 buy was Apellis Pharmaceuticals: 130,000 shares worth $7.64M.
  • Ghost Tree Capital added most to MoonLake Immunotherapeutics in Q1 2024, an estimated $11.9M increase.
  • Ghost Tree Capital's biggest Q1 2024 reduction was Krystal Biotech, cutting an estimated $5M.
  • Ghost Tree Capital fully exited Ambrx Biopharma Inc in Q1 2024, selling an estimated $6.76M.
  • Ghost Tree Capital's ten largest holdings make up 40% of its $361M portfolio in Q1 2024.
  • Ghost Tree Capital opened 33 new positions and closed 13 in Q1 2024.
  • Ghost Tree Capital's portfolio value rose 18% quarter-over-quarter to $361M.

Based on Ghost Tree Capital's 13F filing for Q1 2024, filed 15 May 2024.