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DCM

DAFNA Capital Management Portfolio holdings

AUM $440M
1-Year Est. Return 109.12%
This Fund
S&P 500
This Quarter Est. Return
+14.94%
1 Year Est. Return
+109.12%
3 Year Est. Return
+239.59%
5 Year Est. Return
+227.89%
10 Year Est. Return
+3,611.91%
AUM
$112M
AUM Growth
+$11.4M
Cap. Flow
-$5.75M
Cap. Flow %
-5.12%
Top 10 Hldgs %
46.21%
Holding
94
New
5
Increased
13
Reduced
15
Closed
17

Top Buys

Rank Stock Value
1
CTIC
CTI BioPharma Corp. (DE) Common Stock
CTIC
+$4.27M
2
MRNS
Marinus Pharmaceuticals, Inc
MRNS
+$3.99M
3
VTAE
VITAE PHARMACEUTICALS INC COMMON STOCK
VTAE
+$1.68M
4
LKFT
Lakefront Biotherapeutics American Depositary Shares
LKFT
+$1.45M
5
LOXO
Loxo Oncology, Inc
LOXO
+$1.34M

Top Sells

Rank Stock Value
1
ZSPH
ZS PHARMA INC COMS TK (DE)
ZSPH
+$4.35M
2
ACHN
Achillion Pharmaceuticals
ACHN
+$2.22M
3
OTIC
Otonomy, Inc.
OTIC
+$1.99M
4
XNPT
XENOPORT, INC.
XNPT
+$1.63M
5
PLX icon
Protalix BioTherapeutics
PLX
+$1.41M

Sector Composition

Rank Sector Weight
1 Healthcare 76.52%
2 Financials 0.16%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
APTO
76
DELISTED
Aptose Biosciences, Inc.
APTO
– –
-43
Closed -$83K
OTIC
77
DELISTED
Otonomy, Inc.
OTIC
– –
-111,466
Closed -$1.99M
ADXS
78
DELISTED
Advaxis Inc
ADXS
– –
-333
Closed -$51K
DERM
79
DELISTED
Dermira, Inc.
DERM
– –
-22,500
Closed -$525K
CASM
80
DELISTED
CAS Medical Systems, Inc.
CASM
– –
-86,768
Closed -$108K
CASC
81
DELISTED
Cascadian Therapeutics, Inc.
CASC
– –
-6,030
Closed -$99K
XNPT
82
DELISTED
XENOPORT, INC.
XNPT
– –
-470,612
Closed -$1.63M
ZSPH
83
DELISTED
ZS PHARMA INC COMS TK (DE)
ZSPH
– –
-66,194
Closed -$4.35M
LMNS
84
DELISTED
LUMENIS LTD CL B ORD SHS (ISR)
LMNS
– –
-31,072
Closed -$430K
CEMI
85
DELISTED
Chembio diagnostics, Inc.
CEMI
– –
-21,722
Closed -$88K
CELG
86
DELISTED
Celgene Corp
CELG
– –
-5,200
Closed -$562K
1 2 3
4

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DAFNA Capital Management's Q4 2015 Portfolio in Review

As of Q4 2015, DAFNA Capital Management held 94 positions worth $112M, up 11% from $101M the previous quarter. Its ten largest holdings account for 46% of the portfolio.

DAFNA Capital Management withdrew a net $5.75M in Q4 2015, closing 17 positions and reducing 15 holdings. Its most notable exit was ZS PHARMA INC COMS TK (DE), an estimated $4.35M position sold in full.

By sector, the portfolio is most concentrated in Healthcare at 77% of assets, up from 75% a quarter earlier, followed by Financials.

Against the trend, DAFNA Capital Management opened a new position in CTI BioPharma Corp. (DE) Common Stock worth $3.93M.

  • DAFNA Capital Management's largest Q4 2015 buy was CTI BioPharma Corp. (DE) Common Stock: 319,538 shares worth $3.93M.
  • DAFNA Capital Management added most to Marinus Pharmaceuticals, Inc in Q4 2015, an estimated $3.99M increase.
  • DAFNA Capital Management's biggest Q4 2015 reduction was Achillion Pharmaceuticals, cutting an estimated $2.22M.
  • DAFNA Capital Management fully exited ZS PHARMA INC COMS TK (DE) in Q4 2015, selling an estimated $4.35M.
  • DAFNA Capital Management's ten largest holdings make up 46% of its $112M portfolio in Q4 2015.
  • DAFNA Capital Management opened 5 new positions and closed 17 in Q4 2015.
  • DAFNA Capital Management's portfolio value rose 11% quarter-over-quarter to $112M.

Based on DAFNA Capital Management's 13F filing for Q4 2015, filed 12 Feb 2016.