Avidity Partners Management’s Vertex Pharmaceuticals VRTX Stock Holding History

Bought

Maintained

Sold

Quarter	Market Value	Status	Shares	Change in Stake	Trade Value	Portfolio Weight	Portfolio Position
2023 Q1	–	Sell	-172,000	Closed	-$49.7M	–	94
2022 Q4	$49.7M	Sell	172,000 -340,800	-66%	-$104M	1.16%	31
2022 Q3	$148M	Sell	512,800 -280,200	-35%	-$80.6M	3.23%	8
2022 Q2	$223M	Buy	793,000 +247,400	+45%	+$66.2M	5.13%	2
2022 Q1	$142M	Buy	545,600 +265,600	+95%	+$63M	3.16%	11
2021 Q4	$61.5M	Sell	280,000 -646,400	-70%	-$126M	1.3%	28
2021 Q3	$168M	Sell	926,400 -23,600	-2%	-$4.61M	4.28%	6
2021 Q2	$192M	Buy	950,000 +639,100	+206%	+$134M	5.18%	1
2021 Q1	$66.8M	Buy	310,900 +163,600	+111%	+$35.9M	1.86%	16
2020 Q4	$34.8M	Buy	+147,300	New	+$33.8M	1.17%	33
2020 Q2	–	Sell	-34,000	Closed	-$8.09M	–	78
2020 Q1	$8.09M	Sell	34,000 -6,000	-15%	-$1.38M	1.16%	32
2019 Q4	$8.76M	Buy	+40,000	New	+$8.1M	5.52%	3