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LAB

Nombre Posición Valor operado Cambio en
acciones 		Cambio en la
participación
Primecap Management
1
Primecap Management
California
USD 90.4 M +USD 1.08 M +38,300 +1%
Jennison Associates
2
Jennison Associates
New York
USD 77.7 M +USD 2.44 M +86,738 +3%
JP Morgan Chase
3
JP Morgan Chase
New York
USD 61.7 M +USD 370 k +13,175 +0.5%
OrbiMed
4
OrbiMed
New York
USD 51.5 M +USD 6.69 M +238,000 +13%
Franklin Resources
5
Franklin Resources
California
USD 46.4 M +USD 15.3 M +544,577 +40%
Wasatch Advisors
6
Wasatch Advisors
Utah
USD 43.4 M +USD 860 k +30,588 +2%
Next Century Growth Investors
7
Next Century Growth Investors
Minnesota
USD 36.6 M +USD 6.79 M +241,495 +19%
Fidelity Investments
8
Fidelity Investments
Massachusetts
USD 25.2 M -USD 2.79 M -99,302 -9%
Vanguard Group
9
Vanguard Group
Pennsylvania
USD 20.9 M +USD 186 k +6,612 +0.8%
Invesco
10
Invesco
Georgia
USD 20.5 M +USD 14.7 M +521,223 +165%
BlackRock Fund Advisors
11
BlackRock Fund Advisors
California
USD 18.6 M -USD 788 k -28,018 -4%
Lord, Abbett & Co
12
Lord, Abbett & Co
New Jersey
USD 18.4 M +USD 2.55 M +90,692 +14%
Schroder Investment Management Group
13
Schroder Investment Management Group
United Kingdom
USD 14.3 M +USD 8.26 M +293,800 +101%
Redmile Group
14
Redmile Group
California
USD 13.7 M +USD 4.7 M +167,082 +43%
Luther King Capital Management (LKCM)
15
Luther King Capital Management (LKCM)
Texas
USD 13.7 M +USD 15.7 M +559,231 Nuevas
RS Investment Management
16
RS Investment Management
California
USD 13.2 M +USD 340 k +12,100 +2%
Zevenbergen Capital Investments
17
Zevenbergen Capital Investments
Washington
USD 11.2 M -USD 3.29 M -116,850 -20%
State Street
18
State Street
Massachusetts
USD 10.2 M +USD 27.3 k +972 +0.2%
Northern Trust
19
Northern Trust
Illinois
USD 8.87 M +USD 1.17 M +41,751 +13%
BlackRock Institutional Trust
20
BlackRock Institutional Trust
California
USD 7.97 M -USD 547 k -19,454 -6%
CI Global Investments
21
CI Global Investments
California
USD 7.52 M +USD 197 k +7,000 +2%
Stephens Investment Management Group
22
Stephens Investment Management Group
Texas
USD 6.69 M +USD 1.23 M +43,715 +19%
Millennium Management
23
Millennium Management
New York
USD 5.82 M -USD 781 k -27,784 -10%
Russell Frank Company
24
Russell Frank Company
Washington
USD 5.74 M +USD 929 k +33,052 +16%
FC
25
FIC Capital
New York
USD 4.62 M +USD 5.31 M +188,700 Nuevas
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