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IRON

Nombre Posición Valor operado Cambio en
acciones 		Cambio en la
participación
Fidelity Investments
1
Fidelity Investments
Massachusetts
USD 358 M -USD 47.6 M -692,421 -12%
BlackRock
2
BlackRock
New York
USD 181 M +USD 13.3 M +194,068 +9%
RA Capital Management
3
RA Capital Management
Massachusetts
USD 179 M – – –
JP Morgan Chase
4
JP Morgan Chase
New York
USD 140 M +USD 34.7 M +504,315 +37%
T. Rowe Price Associates
5
T. Rowe Price Associates
Maryland
USD 137 M +USD 22.4 M +326,049 +21%
Wellington Management Group
6
Wellington Management Group
Massachusetts
USD 127 M +USD 411 k +5,975 +0.3%
State Street
7
State Street
Massachusetts
USD 121 M -USD 3.4 M -49,408 -3%
Vestal Point Capital
8
Vestal Point Capital
New York
USD 113 M +USD 58.4 M +850,000 +121%
Atlas Venture Life Science Advisors
9
Atlas Venture Life Science Advisors
Massachusetts
USD 111 M – – –
Vanguard Capital Management
10
Vanguard Capital Management
Pennsylvania
USD 100 M -USD 440 k -6,403 -0.5%
Frazier Life Sciences Management
11
Frazier Life Sciences Management
California
USD 99.1 M – – –
TCG Crossover Management
12
TCG Crossover Management
California
USD 98.1 M – – –
BVF Inc
13
BVF Inc
California
USD 84.4 M -USD 8.16 M -118,700 -9%
Woodline Partners
14
Woodline Partners
California
USD 70.1 M – – –
SL
15
Siren LLC
Connecticut
USD 65 M -USD 6.87 M -100,000 -10%
Logos Global Management
16
Logos Global Management
California
USD 64 M +USD 21.6 M +315,000 +56%
OM
17
Opaleye Management
Massachusetts
USD 62.5 M +USD 29.8 M +434,000 +103%
Geode Capital Management
18
Geode Capital Management
Massachusetts
USD 57.8 M +USD 3.13 M +45,502 +6%
Deerfield Management
19
Deerfield Management
New York
USD 48.1 M – – –
Dimensional Fund Advisors
20
Dimensional Fund Advisors
Texas
USD 41.6 M +USD 12 M +174,571 +44%
Bellevue Group
21
Bellevue Group
Switzerland
USD 41 M +USD 6.92 M +100,686 +22%
SVCM
22
Saturn V Capital Management
Texas
USD 38.4 M +USD 5.14 M +74,804 +17%
Armistice Capital
23
Armistice Capital
New York
USD 33.6 M -USD 5.22 M -76,000 -14%
Jennison Associates
24
Jennison Associates
New York
USD 32.1 M -USD 11.7 M -170,862 -28%
Aberdeen Group
25
Aberdeen Group
United Kingdom
USD 32 M +USD 4.3 M +62,560 +17%
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