|
1
|
Fidelity Investments
Boston,
Massachusetts
|
337 Mio. $
|
+204 Mio. $
|
+5.597.094
|
+729 %
|
|
|
2
|
Novo Holdings A/S
Hellerup,
Denmark
|
103 Mio. $
|
-45,5 Mio. $
|
-1.250.000
|
-39 %
|
|
|
3
|
Millennium Management
New York
|
78 Mio. $
|
+35,8 Mio. $
|
+985.135
|
+202 %
|
|
|
4
|
Eagle Asset Management
St Petersburg,
Florida
|
73,5 Mio. $
|
+9,45 Mio. $
|
+259.737
|
+23 %
|
|
|
5
|
AllianceBernstein
Nashville,
Tennessee
|
69,9 Mio. $
|
-155.373 $
|
-4.272
|
-0,3 %
|
|
|
6
|
TPG Group Holdings (SBS) Advisors
Fort Worth,
Texas
|
65,6 Mio. $
|
-45,5 Mio. $
|
-1.250.000
|
-50 %
|
|
|
7
|
Vanguard Group
Malvern,
Pennsylvania
|
65 Mio. $
|
+23,1 Mio. $
|
+634.874
|
+107 %
|
|
|
8
|
BB Biotech
Schaffhausen,
Switzerland
|
61,2 Mio. $
|
+42 Mio. $
|
+1.155.150
|
Neu
|
|
|
9
|
BlackRock Fund Advisors
San Francisco,
California
|
51,8 Mio. $
|
+8,15 Mio. $
|
+224.075
|
+30 %
|
|
|
10
|
Amundi Asset Management US
Boston,
Massachusetts
|
49,5 Mio. $
|
+34 Mio. $
|
+934.777
|
Neu
|
|
|
11
|
Baker Bros. Advisors
New York
|
47,2 Mio. $
|
+440.332 $
|
+12.107
|
+1 %
|
|
|
12
|
Janus Henderson Investors US
Denver,
Colorado
|
45,7 Mio. $
|
+31,4 Mio. $
|
+863.315
|
Neu
|
|
|
13
|
State Street
Boston,
Massachusetts
|
44,5 Mio. $
|
-5,56 Mio. $
|
-152.860
|
-15 %
|
|
|
14
|
Point72 Asset Management
Stamford,
Connecticut
|
43,4 Mio. $
|
+14,6 Mio. $
|
+400.167
|
+95 %
|
|
|
15
|
Cormorant Asset Management
Boston,
Massachusetts
|
40,1 Mio. $
|
+16 Mio. $
|
+440.000
|
+139 %
|
|
|
16
|
PFM Health Sciences
San Francisco,
California
|
39,9 Mio. $
|
+4,47 Mio. $
|
+122.815
|
+19 %
|
|
|
17
|
BlackRock Advisors
Wilmington,
Delaware
|
36,3 Mio. $
|
+275.430 $
|
+7.573
|
+1 %
|
|
|
18
|
Sectoral Asset Management
Montreal,
Quebec, Canada
|
36,2 Mio. $
|
-14,2 Mio. $
|
-389.701
|
-36 %
|
|
|
19
|
New Leaf Venture Partners
New York
|
34,8 Mio. $
|
+890.701 $
|
+24.490
|
+4 %
|
|
|
20
|
|
31,8 Mio. $
|
-250.626 $
|
-6.891
|
-1 %
|
|
|
21
|
Citadel Advisors
Miami,
Florida
|
30,3 Mio. $
|
-6,62 Mio. $
|
-181.912
|
-24 %
|
|
|
22
|
Cadian Capital Management
New York
|
22,5 Mio. $
|
+13,5 Mio. $
|
+370.000
|
+673 %
|
|
|
23
|
Foresite Capital Management II
Larkspur,
California
|
18,3 Mio. $
|
+6,82 Mio. $
|
+187.639
|
+119 %
|
|
|
24
|
BlackRock Group
London,
United Kingdom
|
17,8 Mio. $
|
+622.873 $
|
+17.126
|
+5 %
|
|
|
25
|
BlackRock Institutional Trust
San Francisco,
California
|
17,2 Mio. $
|
+4,26 Mio. $
|
+117.242
|
+56 %
|
|
