|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$337M
|
+$204M
|
+5,597,094
|
+729%
|
|
|
2
|
Novo Holdings A/S
Hellerup,
Denmark
|
$103M
|
-$45.5M
|
-1,250,000
|
-39%
|
|
|
3
|
Millennium Management
New York
|
$78M
|
+$35.8M
|
+985,135
|
+202%
|
|
|
4
|
Eagle Asset Management
St Petersburg,
Florida
|
$73.5M
|
+$9.45M
|
+259,737
|
+23%
|
|
|
5
|
AllianceBernstein
Nashville,
Tennessee
|
$69.9M
|
-$155K
|
-4,272
|
-0.3%
|
|
|
6
|
TPG Group Holdings (SBS) Advisors
Fort Worth,
Texas
|
$65.6M
|
-$45.5M
|
-1,250,000
|
-50%
|
|
|
7
|
Vanguard Group
Malvern,
Pennsylvania
|
$65M
|
+$23.1M
|
+634,874
|
+107%
|
|
|
8
|
BB Biotech
Schaffhausen,
Switzerland
|
$61.2M
|
+$42M
|
+1,155,150
|
New
|
|
|
9
|
BlackRock Fund Advisors
San Francisco,
California
|
$51.8M
|
+$8.15M
|
+224,075
|
+30%
|
|
|
10
|
Amundi Asset Management US
Boston,
Massachusetts
|
$49.5M
|
+$34M
|
+934,777
|
New
|
|
|
11
|
Baker Bros. Advisors
New York
|
$47.2M
|
+$440K
|
+12,107
|
+1%
|
|
|
12
|
Janus Henderson Investors US
Denver,
Colorado
|
$45.7M
|
+$31.4M
|
+863,315
|
New
|
|
|
13
|
State Street
Boston,
Massachusetts
|
$44.5M
|
-$5.56M
|
-152,860
|
-15%
|
|
|
14
|
Point72 Asset Management
Stamford,
Connecticut
|
$43.4M
|
+$14.6M
|
+400,167
|
+95%
|
|
|
15
|
Cormorant Asset Management
Boston,
Massachusetts
|
$40.1M
|
+$16M
|
+440,000
|
+139%
|
|
|
16
|
PFM Health Sciences
San Francisco,
California
|
$39.9M
|
+$4.47M
|
+122,815
|
+19%
|
|
|
17
|
BlackRock Advisors
Wilmington,
Delaware
|
$36.3M
|
+$275K
|
+7,573
|
+1%
|
|
|
18
|
Sectoral Asset Management
Montreal,
Quebec, Canada
|
$36.2M
|
-$14.2M
|
-389,701
|
-36%
|
|
|
19
|
New Leaf Venture Partners
New York
|
$34.8M
|
+$891K
|
+24,490
|
+4%
|
|
|
20
|
|
$31.8M
|
-$251K
|
-6,891
|
-1%
|
|
|
21
|
Citadel Advisors
Miami,
Florida
|
$30.3M
|
-$6.62M
|
-181,912
|
-24%
|
|
|
22
|
Cadian Capital Management
New York
|
$22.5M
|
+$13.5M
|
+370,000
|
+673%
|
|
|
23
|
Foresite Capital Management II
Larkspur,
California
|
$18.3M
|
+$6.82M
|
+187,639
|
+119%
|
|
|
24
|
BlackRock Group
London,
United Kingdom
|
$17.8M
|
+$623K
|
+17,126
|
+5%
|
|
|
25
|
BlackRock Institutional Trust
San Francisco,
California
|
$17.2M
|
+$4.26M
|
+117,242
|
+56%
|
|
