|
26
|
T. Rowe Price Investment Management
Baltimore,
Maryland
|
$810M
|
-$710M
|
7
|
0.56%
|
Reduced
|
|
|
27
|
ARK Investment Management
St. Petersburg,
Florida
|
$747M
|
+$49.6M
|
4
|
5.81%
|
Increased
|
|
|
28
|
Citadel Advisors
Miami,
Florida
|
$745M
|
+$35.7M
|
60
|
0.12%
|
Increased
|
|
|
29
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$722M
|
+$30.2M
|
36
|
0.08%
|
Increased
|
|
|
30
|
Farallon Capital Management
San Francisco,
California
|
$706M
|
+$29.5M
|
7
|
3.7%
|
Increased
|
|
|
31
|
Paradigm Biocapital Advisors
New York
|
$698M
|
-$37.9M
|
2
|
14.27%
|
Reduced
|
|
|
32
|
Two Sigma Investments
New York
|
$696M
|
+$324M
|
52
|
0.56%
|
Increased
|
|
|
33
|
|
$694M
|
+$45.6M
|
69
|
0.04%
|
Increased
|
|
|
34
|
Millennium Management
New York
|
$628M
|
+$306M
|
51
|
0.26%
|
Increased
|
|
|
35
|
Charles Schwab
San Francisco,
California
|
$604M
|
+$13.5M
|
48
|
0.09%
|
Increased
|
|
|
36
|
RA Capital Management
Boston,
Massachusetts
|
$533M
|
+$49.4M
|
11
|
5.65%
|
Increased
|
|
|
37
|
Suvretta Capital Management
New York
|
$528M
|
-$13.6M
|
8
|
13.49%
|
Reduced
|
|
|
38
|
|
$520M
|
-$27.6M
|
27
|
0.31%
|
Reduced
|
|
|
39
|
Ameriprise
Minneapolis,
Minnesota
|
$507M
|
-$29.2M
|
26
|
0.12%
|
Reduced
|
|
|
40
|
Allspring Global Investments
Charlotte,
North Carolina
|
$458M
|
-$7.24M
|
9
|
0.77%
|
Reduced
|
|
|
41
|
Raymond James Financial
St Petersburg,
Florida
|
$447M
|
+$55.6M
|
34
|
0.14%
|
Increased
|
|
|
42
|
Principal Financial Group
Des Moines,
Iowa
|
$443M
|
-$50.4M
|
11
|
0.24%
|
Reduced
|
|
|
43
|
Capital World Investors
Los Angeles,
California
|
$439M
|
+$255M
|
3
|
0.06%
|
Increased
|
|
|
44
|
Frazier Life Sciences Management
Palo Alto,
California
|
$421M
|
-$9.38M
|
5
|
10.84%
|
Reduced
|
|
|
45
|
Vanguard Fiduciary Trust
Malvern,
Pennsylvania
|
$414M
|
+$418M
|
74
|
0.1%
|
New
|
|
|
46
|
NEA Management Company
Timonium,
Maryland
|
$413M
|
$0
|
5
|
23.46%
|
Maintained
|
|
|
47
|
Envestnet Asset Management
Chicago,
Illinois
|
$400M
|
+$93.1M
|
17
|
0.11%
|
Increased
|
|
|
48
|
Renaissance Technologies
New York
|
$395M
|
-$6.05M
|
56
|
0.62%
|
Reduced
|
|
|
49
|
SR One Capital Management
Wayne,
Pennsylvania
|
$381M
|
$0
|
5
|
41.67%
|
Maintained
|
|
|
50
|
Soleus Capital Management
Greenwich,
Connecticut
|
$380M
|
+$98.3M
|
2
|
15.38%
|
Increased
|
|