PBA

Paradigm Biocapital Advisors Portfolio holdings

AUM $2.34B
This Quarter Return
+2.84%
1 Year Return
+13.3%
3 Year Return
+245.82%
5 Year Return
–
10 Year Return
–
AUM
$2.34B
AUM Growth
+$2.34B
Cap. Flow
+$178M
Cap. Flow %
7.61%
Top 10 Hldgs %
72.34%
Holding
33
New
6
Increased
14
Reduced
5
Closed
5

Top Buys

1
SRRK icon
Scholar Rock
SRRK
$56.7M
2
PCVX icon
Vaxcyte
PCVX
$54.5M
3
MRUS icon
Merus
MRUS
$48M
4
BBIO icon
BridgeBio Pharma
BBIO
$41.7M
5
ALKS icon
Alkermes
ALKS
$39.4M

Top Sells

1
ONC
BeOne Medicines Ltd. American Depositary Shares
ONC
$77M
2
ARGX icon
argenx
ARGX
$35.3M
3
CYTK icon
Cytokinetics
CYTK
$34.5M
4
INSM icon
Insmed
INSM
$34.4M
5
MTSR
Metsera, Inc. Common Stock
MTSR
$32.4M

Sector Composition

1 Healthcare 100%
Name Market Value Portfolio Weight Shares or Principal Shares
Change % 		Capital Flow
NUVL icon
1
Nuvalent
NUVL
$5.45B
$402M 17.17%
5,269,433
– –
ACLX icon
2
Arcellx
ACLX
$3.88B
$306M 13.07%
4,649,016
+156,984
+3% +$10.3M
MRUS icon
3
Merus
MRUS
$5.03B
$225M 9.62%
4,281,954
+912,255
+27% +$48M
RVMD icon
4
Revolution Medicines
RVMD
$7.28B
$224M 9.57%
6,093,291
-84,820
-1% -$3.12M
TARS icon
5
Tarsus Pharmaceuticals
TARS
$2.49B
$121M 5.15%
2,976,099
+365,902
+14% +$14.8M
PCVX icon
6
Vaxcyte
PCVX
$4.08B
$110M 4.68%
3,372,837
+1,676,356
+99% +$54.5M
ONC
7
BeOne Medicines Ltd. American Depositary Shares
ONC
$39.2B
$84.2M 3.59%
347,787
-318,237
-48% -$77M
EWTX icon
8
Edgewise Therapeutics
EWTX
$1.59B
$80.5M 3.44%
6,142,344
+1,747,788
+40% +$22.9M
COGT icon
9
Cogent Biosciences
COGT
$1.69B
$74.3M 3.17%
10,352,449
+1,388,794
+15% +$9.97M
JANX icon
10
Janux Therapeutics
JANX
$1.36B
$67.5M 2.88%
2,920,258
-409,651
-12% -$9.46M
CRNX icon
11
Crinetics Pharmaceuticals
CRNX
$3.09B
$67.4M 2.88%
2,343,553
+397,385
+20% +$11.4M
IRON icon
12
Disc Medicine
IRON
$2.07B
$64.1M 2.74%
1,210,971
– –
SRRK icon
13
Scholar Rock
SRRK
$3.14B
$56.7M 2.42%
+1,600,554
New +$56.7M
LENZ
14
LENZ Therapeutics
LENZ
$1.11B
$50.3M 2.15%
1,717,066
+205,134
+14% +$6.01M
BBIO icon
15
BridgeBio Pharma
BBIO
$9.92B
$41.7M 1.78%
+965,764
New +$41.7M
APGE icon
16
Apogee Therapeutics
APGE
$2.23B
$41.6M 1.78%
958,630
-3,077
-0.3% -$134K
MLTX icon
17
MoonLake Immunotherapeutics
MLTX
$3.67B
$41.5M 1.77%
878,323
+250,900
+40% +$11.8M
ALKS icon
18
Alkermes
ALKS
$4.85B
$39.4M 1.68%
+1,375,569
New +$39.4M
VRDN icon
19
Viridian Therapeutics
VRDN
$1.53B
$38.3M 1.64%
2,741,576
+646,497
+31% +$9.04M
AGIO icon
20
Agios Pharmaceuticals
AGIO
$2.24B
$38M 1.62%
+1,142,511
New +$38M
OCUL icon
21
Ocular Therapeutix
OCUL
$2.19B
$31.7M 1.36%
3,420,340
+2,106,322
+160% +$19.5M
OLMA icon
22
Olema Pharmaceuticals
OLMA
$420M
$28.8M 1.23%
6,764,172
+23,000
+0.3% +$98K
SYRE icon
23
Spyre Therapeutics
SYRE
$1.01B
$28M 1.2%
1,870,445
-256,760
-12% -$3.84M
YMAB icon
24
Y-mAbs Therapeutics
YMAB
$389M
$19.1M 0.82%
4,236,346
– –
PHVS icon
25
Pharvaris
PHVS
$1.45B
$18.7M 0.8%
+1,062,911
New +$18.7M
1
2