PBA

Paradigm Biocapital Advisors Portfolio holdings

AUM $2.34B
1-Year Est. Return 13.3%
This Quarter Est. Return
1 Year Est. Return
+13.3%
3 Year Est. Return
5 Year Est. Return
10 Year Est. Return
AUM
$2.17B
AUM Growth
-$702M
Cap. Flow
Cap. Flow %
Top 10 Hldgs %
Holding
33
New
Increased
Reduced
Closed

Top Buys

1 +$70.7M
2 +$34.5M
3 +$34.4M
4
MTSR
Metsera Inc
MTSR
+$32.4M
5
COGT icon
Cogent Biosciences
COGT
+$24.2M

Top Sells

1 +$250M
2 +$60.8M
3 +$44.7M
4
PLRX icon
Pliant Therapeutics
PLRX
+$42.1M
5
TECX
Tectonic Therapeutic
TECX
+$22.4M

Sector Composition

1 Healthcare 100%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake
Capital Flow
NUVL icon
1
Nuvalent
NUVL
$6.52B
$374M 17.12%
5,269,433
-93,946
ACLX icon
2
Arcellx
ACLX
$4.93B
$295M 13.5%
4,492,032
+120,431
RVMD icon
3
Revolution Medicines
RVMD
$9.29B
$218M 10.01%
6,178,111
-375,000
ONC
4
BeOne Medicines Ltd
ONC
$34.9B
$181M 8.3%
666,024
+50,000
MRUS icon
5
Merus
MRUS
$7.19B
$142M 6.5%
3,369,699
+1,679,777
TARS icon
6
Tarsus Pharmaceuticals
TARS
$3.16B
$134M 6.14%
2,610,197
+78,301
EWTX icon
7
Edgewise Therapeutics
EWTX
$1.61B
$96.7M 4.43%
4,394,556
-99,373
JANX icon
8
Janux Therapeutics
JANX
$1.63B
$89.9M 4.12%
3,329,909
-186,077
CRNX icon
9
Crinetics Pharmaceuticals
CRNX
$3.98B
$65.3M 2.99%
1,946,168
+35,407
PCVX icon
10
Vaxcyte
PCVX
$5.66B
$64.1M 2.93%
1,696,481
+273,694
IRON icon
11
Disc Medicine
IRON
$2.59B
$60.1M 2.75%
1,210,971
-286,749
COGT icon
12
Cogent Biosciences
COGT
$2.29B
$53.7M 2.46%
8,963,655
+4,046,243
LENZ
13
LENZ Therapeutics
LENZ
$1.22B
$38.9M 1.78%
1,511,932
+741,477
APGE icon
14
Apogee Therapeutics
APGE
$3.61B
$35.9M 1.65%
961,707
-322,059
ARGX icon
15
argenx
ARGX
$51.6B
$35.3M 1.62%
59,679
-421,626
CYTK icon
16
Cytokinetics
CYTK
$7.05B
$34.5M 1.58%
+858,664
INSM icon
17
Insmed
INSM
$34.5B
$34.4M 1.58%
+451,359
SYRE icon
18
Spyre Therapeutics
SYRE
$1.72B
$34.3M 1.57%
2,127,205
+600,000
MTSR
19
Metsera Inc
MTSR
$5.57B
$32.4M 1.49%
+1,191,462
VRDN icon
20
Viridian Therapeutics
VRDN
$1.88B
$28.2M 1.29%
2,095,079
+275,000
OLMA icon
21
Olema Pharmaceuticals
OLMA
$659M
$25.3M 1.16%
6,741,172
-563,798
MLTX icon
22
MoonLake Immunotherapeutics
MLTX
$596M
$24.5M 1.12%
627,423
-1,144,788
ARQT icon
23
Arcutis Biotherapeutics
ARQT
$2.51B
$22.9M 1.05%
+1,465,334
YMAB
24
DELISTED
Y-mAbs Therapeutics
YMAB
$18.8M 0.86%
4,236,346
ERAS icon
25
Erasca
ERAS
$718M
$14.8M 0.68%
10,802,354
+50,000