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NEA Management Company

NEA Management Company Portfolio holdings

AUM $1.59B Turnover 7.41%
1-Year Est. Return 234.06%
This Fund
S&P 500
This Quarter Est. Return
+26.7%
1 Year Est. Return
+234.06%
3 Year Est. Return
+822.97%
5 Year Est. Return
+865.41%
10 Year Est. Return
+12,585.11%
AUM
$1.59B
AUM Growth
-$171M
Cap. Flow
-$411M
Cap. Flow %
-25.91%
Top 10 Hldgs %
89.82%
Holding
27
New
1
Increased
–
Reduced
2
Closed
1
Avg Time Held
4.6 years
Top 10 Avg Time Held
1.2 years
Top 20 Avg Time Held
2.4 years

Top Buys

Rank Stock Value
1
KPTI icon
Karyopharm Therapeutics
KPTI
+$5M

Top Sells

Rank Stock Value
1
ACLX icon
Arcellx
ACLX
+$350M
2
CELC icon
Celcuity
CELC
+$66.3M
3
CVRX icon
CVRx
CVRX
+$462K

Sector Composition

Rank Sector Weight
1 Healthcare 95.43%
2 Consumer Staples 4.57%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake
Capital Flow Held Since
TRVI icon
1
Trevi Therapeutics
TRVI
$1.69B
$247M 15.53%
13,222,228
– –
2019 Q2
28 quarters
MBX icon
2
MBX Biosciences
MBX
$2.5B
$200M 12.56%
3,614,486
– –
2024 Q3
7 quarters
GLUE icon
3
Monte Rosa Therapeutics
GLUE
$852M
$186M 11.72%
7,692,298
– –
2021 Q2
20 quarters
CELC icon
4
Celcuity
CELC
$2.84B
$179M 11.27%
1,710,561
-575,000
-25% -$66.3M
2022 Q4
14 quarters
SGP icon
5
SpyGlass Pharma
SGP
$831M
$165M 10.36%
7,392,301
– –
2026 Q1
1 quarter
SVRA icon
6
Savara
SVRA
$939M
$151M 9.49%
24,471,264
– –
2021 Q1
21 quarters
ZBIO icon
7
Zenas BioPharma
ZBIO
$1.75B
$102M 6.43%
4,023,219
– –
2024 Q3
7 quarters
COUR icon
8
Coursera
COUR
$1.31B
$72.6M 4.57%
12,867,769
– –
2021 Q1
21 quarters
AUPH icon
9
Aurinia Pharmaceuticals
AUPH
$2.2B
$67.4M 4.24%
3,969,834
– –
2014 Q3
47 quarters
CRSP icon
10
CRISPR Therapeutics
CRSP
$4.81B
$57.7M 3.64%
1,058,570
– –
2016 Q4
38 quarters
ORIC icon
11
Oric Pharmaceuticals
ORIC
$1.29B
$44.6M 2.81%
4,118,621
– –
2024 Q1
9 quarters
PHAT icon
12
Phathom Pharmaceuticals
PHAT
$550M
$21.3M 1.34%
1,960,169
– –
2023 Q2
12 quarters
KRRO icon
13
Korro Bio
KRRO
$126M
$17.1M 1.08%
1,297,893
– –
2023 Q4
10 quarters
XFOR icon
14
X4 Pharmaceuticals
XFOR
$263M
$15.1M 0.95%
3,233,743
– –
2022 Q3
15 quarters
CSBR icon
15
Champions Oncology
CSBR
$65M
$10.6M 0.66%
1,713,720
– –
2015 Q3
43 quarters
NKTX icon
16
Nkarta
NKTX
$128M
$10.1M 0.64%
3,568,781
– –
2020 Q3
23 quarters
CVRX icon
17
CVRx
CVRX
$34.1M
$10M 0.63%
1,954,440
-71,643
-4% -$462K
2021 Q2
20 quarters
BDTX icon
18
Black Diamond Therapeutics
BDTX
$101M
$8.23M 0.52%
4,448,757
– –
2020 Q1
25 quarters
KPTI icon
19
Karyopharm Therapeutics
KPTI
$8.05M
$5.64M 0.35%
+576,780
New +$5M
2026 Q2
0 quarters
IVA icon
20
Inventiva
IVA
$711M
$5.53M 0.35%
1,462,586
– –
2020 Q3
23 quarters
LONA icon
21
LeonaBio Inc
LONA
$48.8M
$4.27M 0.27%
464,398
– –
2025 Q4
2 quarters
SNTI icon
22
Senti Biosciences Holdings
SNTI
$6.95M
$4.15M 0.26%
3,775,615
– –
2022 Q2
16 quarters
MRKR icon
23
Marker Therapeutics
MRKR
$18M
$2.39M 0.15%
1,625,678
– –
2018 Q4
30 quarters
OKUR icon
24
OnKure Therapeutics
OKUR
$83.4M
$2.18M 0.14%
478,548
– –
2021 Q2
20 quarters
IMA icon
25
ImageneBio Inc
IMA
$45.4M
$295K 0.02%
50,005
– –
2023 Q3
11 quarters

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NEA Management Company's Q2 2026 Portfolio in Review

As of Q2 2026, NEA Management Company held 27 positions worth $1.59B, down 9.7% from $1.76B the previous quarter. Its ten largest holdings account for 90% of the portfolio.

NEA Management Company withdrew a net $411M in Q2 2026, closing 1 position and reducing 2 holdings. Its most notable exit was Arcellx, an estimated $350M position sold in full.

By sector, the portfolio is most concentrated in Healthcare at 95% of assets, down from 96% a quarter earlier, followed by Consumer Staples.

Against the trend, NEA Management Company opened a new position in Karyopharm Therapeutics worth $5.64M.

  • NEA Management Company's largest Q2 2026 buy was Karyopharm Therapeutics: 576,780 shares worth $5.64M.
  • NEA Management Company's biggest Q2 2026 reduction was Celcuity, cutting an estimated $66.3M.
  • NEA Management Company fully exited Arcellx in Q2 2026, selling an estimated $350M.
  • NEA Management Company's ten largest holdings make up 90% of its $1.59B portfolio in Q2 2026.
  • NEA Management Company opened 1 new position and closed 1 in Q2 2026.
  • NEA Management Company's portfolio value fell 9.7% quarter-over-quarter to $1.59B.

Based on NEA Management Company's 13F filing for Q2 2026, filed 14 Aug 2026.