|
26
|
T. Rowe Price Investment Management
Baltimore,
Maryland
|
$532M
|
-$2.97M
|
7
|
0.34%
|
Reduced
|
|
|
27
|
|
$488M
|
-$166K
|
69
|
0.03%
|
Reduced
|
|
|
28
|
Avoro Capital Advisors
New York
|
$478M
|
-$191M
|
4
|
8.38%
|
Reduced
|
|
|
29
|
Renaissance Technologies
New York
|
$456M
|
+$77.5M
|
57
|
0.61%
|
Increased
|
|
|
30
|
Suvretta Capital Management
New York
|
$438M
|
+$28.8M
|
10
|
13.22%
|
Increased
|
|
|
31
|
|
$426M
|
+$402M
|
21
|
0.3%
|
Increased
|
|
|
32
|
Allspring Global Investments
Charlotte,
North Carolina
|
$407M
|
+$92.9M
|
11
|
0.68%
|
Increased
|
|
|
33
|
Charles Schwab
San Francisco,
California
|
$402M
|
+$11.7M
|
48
|
0.07%
|
Increased
|
|
|
34
|
Millennium Management
New York
|
$397M
|
+$152M
|
58
|
0.19%
|
Increased
|
|
|
35
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$388M
|
-$277M
|
37
|
0.04%
|
Reduced
|
|
|
36
|
Perceptive Advisors
New York
|
$384M
|
-$15.4M
|
8
|
14.22%
|
Reduced
|
|
|
37
|
Farallon Capital Management
San Francisco,
California
|
$379M
|
-$67.5M
|
8
|
1.59%
|
Reduced
|
|
|
38
|
Principal Financial Group
Des Moines,
Iowa
|
$371M
|
-$18M
|
12
|
0.2%
|
Reduced
|
|
|
39
|
Paradigm Biocapital Advisors
New York
|
$365M
|
+$51M
|
3
|
15.57%
|
Increased
|
|
|
40
|
Two Sigma Investments
New York
|
$359M
|
+$149M
|
49
|
0.64%
|
Increased
|
|
|
41
|
NEA Management Company
Timonium,
Maryland
|
$344M
|
$0
|
6
|
25.92%
|
Maintained
|
|
|
42
|
Balyasny Asset Management
Chicago,
Illinois
|
$341M
|
+$163M
|
18
|
0.51%
|
Increased
|
|
|
43
|
RA Capital Management
Boston,
Massachusetts
|
$337M
|
+$23M
|
7
|
5.68%
|
Increased
|
|
|
44
|
Frazier Life Sciences Management
Palo Alto,
California
|
$330M
|
+$10.3M
|
7
|
13.18%
|
Increased
|
|
|
45
|
Capital International Investors
Los Angeles,
California
|
$319M
|
-$430M
|
3
|
0.06%
|
Reduced
|
|
|
46
|
Vestal Point Capital
New York
|
$305M
|
-$19.5M
|
11
|
16.08%
|
Reduced
|
|
|
47
|
Wells Fargo
San Francisco,
California
|
$293M
|
-$39.6M
|
70
|
0.06%
|
Reduced
|
|
|
48
|
Citadel Advisors
Miami,
Florida
|
$288M
|
-$249M
|
63
|
0.05%
|
Reduced
|
|
|
49
|
Armistice Capital
New York
|
$286M
|
-$29.8M
|
9
|
4.94%
|
Reduced
|
|
|
50
|
Two Sigma Advisers
New York
|
$277M
|
+$146M
|
33
|
0.57%
|
Increased
|
|