|
26
|
Kohlberg Kravis Roberts & Co
New York
|
$666M
|
-$202M
|
1
|
15.04%
|
Reduced
|
|
|
27
|
Northern Trust
Chicago,
Illinois
|
$650M
|
-$4.39M
|
76
|
0.1%
|
Reduced
|
|
|
28
|
|
$545M
|
+$40.4M
|
80
|
0.04%
|
Increased
|
|
|
29
|
Citadel Advisors
Miami,
Florida
|
$528M
|
+$42.5M
|
62
|
0.1%
|
Increased
|
|
|
30
|
T. Rowe Price Investment Management
Baltimore,
Maryland
|
$519M
|
+$166M
|
9
|
0.34%
|
Increased
|
|
|
31
|
ARK Investment Management
St. Petersburg,
Florida
|
$445M
|
+$50.1M
|
3
|
4.45%
|
Increased
|
|
|
32
|
Suvretta Capital Management
New York
|
$424M
|
+$87M
|
9
|
15.73%
|
Increased
|
|
|
33
|
Charles Schwab
San Francisco,
California
|
$406M
|
+$751K
|
56
|
0.08%
|
Increased
|
|
|
34
|
Farallon Capital Management
San Francisco,
California
|
$380M
|
-$3.14M
|
8
|
1.82%
|
Reduced
|
|
|
35
|
Perceptive Advisors
New York
|
$379M
|
-$25.6M
|
8
|
13.39%
|
Reduced
|
|
|
36
|
Principal Financial Group
Des Moines,
Iowa
|
$375M
|
-$3.34M
|
14
|
0.21%
|
Reduced
|
|
|
37
|
Renaissance Technologies
New York
|
$371M
|
-$44.3M
|
50
|
0.56%
|
Reduced
|
|
|
38
|
Wells Fargo
San Francisco,
California
|
$325M
|
+$3.79M
|
71
|
0.07%
|
Increased
|
|
|
39
|
NEA Management Company
Timonium,
Maryland
|
$324M
|
+$13M
|
6
|
24.98%
|
Increased
|
|
|
40
|
Armistice Capital
New York
|
$321M
|
-$43.3M
|
10
|
4.81%
|
Reduced
|
|
|
41
|
|
$315M
|
+$130M
|
17
|
0.08%
|
Increased
|
|
|
42
|
Frazier Life Sciences Management
Palo Alto,
California
|
$313M
|
-$23.6M
|
9
|
14.31%
|
Reduced
|
|
|
43
|
Deutsche Bank
Frankfurt Am Main Ge,
Germany
|
$312M
|
+$45M
|
49
|
0.12%
|
Increased
|
|
|
44
|
RA Capital Management
Boston,
Massachusetts
|
$310M
|
-$227M
|
9
|
5.18%
|
Reduced
|
|
|
45
|
|
$305M
|
-$22.8M
|
9
|
24.89%
|
Reduced
|
|
|
46
|
Paradigm Biocapital Advisors
New York
|
$303M
|
-$10.1M
|
2
|
13.89%
|
Reduced
|
|
|
47
|
Bank of New York Mellon
New York
|
$298M
|
-$190M
|
54
|
0.06%
|
Reduced
|
|
|
48
|
Vestal Point Capital
New York
|
$297M
|
+$79.4M
|
13
|
21.19%
|
Increased
|
|
|
49
|
Kayne Anderson Rudnick Investment Management
Los Angeles,
California
|
$295M
|
+$24.2M
|
3
|
0.72%
|
Increased
|
|
|
50
|
Allspring Global Investments
Charlotte,
North Carolina
|
$290M
|
-$11.5M
|
12
|
0.5%
|
Reduced
|
|