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Zymeworks

172 hedge funds and large institutions have $973M invested in Zymeworks in 2024 Q4 according to their latest regulatory filings, with 31 funds opening new positions, 47 increasing their positions, 61 reducing their positions, and 20 closing their positions.

New
Increased
Maintained
Reduced
Closed

150% more funds holding in top 10

Funds holding in top 10: 25 (+3)

106% more call options, than puts

Call options by funds: $547K | Put options by funds: $266K

55% more first-time investments, than exits

New positions opened: 31 | Existing positions closed: 20

17% more capital invested

Capital invested by funds: $835M → $973M (+$139M)

6% more funds holding

Funds holding: 163172 (+9)

2.81% more ownership

Funds ownership: 93.7%96.52% (+2.8%)

23% less repeat investments, than reductions

Existing positions increased: 47 | Existing positions reduced: 61

Holders
172
Holders Change
+9
Holders Change %
+5.52%
% of All Funds
2.27%
Holding in Top 10
5
Holding in Top 10 Change
+3
Holding in Top 10 Change %
+150%
% of All Funds
0.07%
New
31
Increased
47
Reduced
61
Closed
20
Calls
$547K
Puts
$266K
Net Calls
+$281K
Net Calls Change
+$7.41M
Name Holding Trade Value Shares
Change
Change in
Stake
Bank of New York Mellon
51
Bank of New York Mellon
New York
$1.77M -$1.81M -129,308 -52%
JP Morgan Chase
52
JP Morgan Chase
New York
$1.64M +$1.02M +72,703 +185%
RhumbLine Advisers
53
RhumbLine Advisers
Massachusetts
$1.52M +$223K +15,920 +18%
TI
54
Trexquant Investment
Connecticut
$1.49M +$1.43M +101,996 New
SFI
55
Susquehanna Fundamental Investments
Pennsylvania
$1.43M +$1.36M +97,553 New
NGM
56
North Growth Management
British Columbia, Canada
$1.42M
HF
57
HRT Financial
New York
$1.41M +$660K +47,166 +97%
Swiss National Bank
58
Swiss National Bank
Switzerland
$1.32M
Citigroup
59
Citigroup
New York
$1.22M +$45.4K +3,246 +4%
Credit Agricole
60
Credit Agricole
France
$1.1M
RWM
61
Ritholtz Wealth Management
New York
$1.09M +$60.1K +4,297 +6%
Invesco
62
Invesco
Georgia
$1.02M -$1.31M -93,657 -57%
ACP
63
Acuta Capital Partners
California
$984K +$940K +67,240 New
State of Wisconsin Investment Board
64
State of Wisconsin Investment Board
Wisconsin
$957K -$277K -19,777 -23%
Stifel Financial
65
Stifel Financial
Missouri
$942K -$130K -9,324 -13%
Fisher Asset Management
66
Fisher Asset Management
Washington
$931K
Royal Bank of Canada
67
Royal Bank of Canada
Ontario, Canada
$893K -$13.3K -952 -2%
Raymond James Financial
68
Raymond James Financial
Florida
$888K +$848K +60,642 New
VOYA Investment Management
69
VOYA Investment Management
Georgia
$871K +$562K +40,172 +208%
Citadel Advisors
70
Citadel Advisors
Florida
$854K +$525K +37,550 +180%
Envestnet Asset Management
71
Envestnet Asset Management
Illinois
$792K -$162K -11,588 -18%
Victory Capital Management
72
Victory Capital Management
Texas
$755K -$39.3K -2,810 -5%
Susquehanna International Group
73
Susquehanna International Group
Pennsylvania
$754K +$491K +35,130 +214%
Ohio Public Employees Retirement System (OPERS)
74
Ohio Public Employees Retirement System (OPERS)
Ohio
$741K -$145K -10,400 -17%
AllianceBernstein
75
AllianceBernstein
Tennessee
$732K

ZYME Hedge Fund Activity: Q4 2024 in Review

172 of the 7,592 institutional investors tracked by Wall St. Rank reported a position in Zymeworks (ZYME) for Q4 2024, worth a combined $973M — up 17% from $835M a quarter earlier.

Buyers outnumbered sellers: 31 funds opened new ZYME positions and 20 closed out — a net gain of 11 holders — while 47 added to existing stakes and 61 trimmed.

The largest buyer was EcoR1 Capital, adding an estimated $22.2M. The largest seller was Morgan Stanley, cutting an estimated $12.7M.

  • 172 institutional investors held Zymeworks (ZYME) as of Q4 2024, up from 163 in Q3 2024.
  • Funds reported $973M of Zymeworks stock for Q4 2024, up 17% quarter-over-quarter.
  • 31 funds opened new Zymeworks positions in Q4 2024 and 20 closed out, a net change of +11 holders.
  • The largest Zymeworks buyer in Q4 2024 was EcoR1 Capital, an estimated $22.2M added.
  • The largest Zymeworks seller in Q4 2024 was Morgan Stanley, an estimated $12.7M sold.

Based on aggregated 13F filings for Q4 2024.