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Zentalis Pharmaceuticals
ZNTL

Overview Fund Activity

117 hedge funds and large institutions have $64.6M invested in Zentalis Pharmaceuticals in 2025 Q2 according to their latest regulatory filings, with 22 funds opening new positions, 34 increasing their positions, 44 reducing their positions, and 37 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
117
Holders Change
-15
Holders Change %
-11.36%
% of All Funds
1.57%
Holding in Top 10
2
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.03%
New
22
Increased
34
Reduced
44
Closed
37
Calls
–
Puts
$73K
Net Calls
-$73K
Net Calls Change
+$84K

Top Buyers

1
Balyasny Asset Management
Balyasny Asset Management
Illinois
$1.13M
2
Renaissance Technologies
Renaissance Technologies
New York
$1.77M
3
GCP
GSA Capital Partners
United Kingdom
$1.32M
4
Two Sigma Investments
Two Sigma Investments
New York
$1.27M
5
TCM
Tybourne Capital Management
Hong Kong
$1.71M

Top Sellers

1
BlackRock
BlackRock
New York
$2.02M
2
State Street
State Street
Massachusetts
$315K
3
Geode Capital Management
Geode Capital Management
Massachusetts
$717K
4
Federated Hermes
Federated Hermes
Pennsylvania
$46.1K
5
DC
Decheng Capital
California
$1.54M
Name Holding Trade Value Shares
Change 		Shares
Change %
MCMC
1
Matrix Capital Management Company
New Hampshire
$16.2M – – –
Millennium Management
2
Millennium Management
New York
$4.03M +$472K +407,294 +13%
Vanguard Group
3
Vanguard Group
Pennsylvania
$3.35M -$436K -375,980 -12%
Acadian Asset Management
4
Acadian Asset Management
Massachusetts
$3.24M +$145K +124,985 +5%
OM
5
Opaleye Management
Massachusetts
$2.23M -$70.4K -60,700 -3%
BlackRock
6
BlackRock
New York
$2.02M -$2.89M -2,487,750 -59%
AC
7
Almitas Capital
California
$1.86M -$130K -111,655 -7%
TCM
8
Tang Capital Management
California
$1.8M +$58K +50,000 +3%
Renaissance Technologies
9
Renaissance Technologies
New York
$1.77M +$816K +703,512 +85%
TCM
10
Tybourne Capital Management
Hong Kong
$1.71M +$599K +516,666 +54%
DC
11
Decheng Capital
California
$1.54M -$808K -696,435 -34%
Two Sigma Advisers
12
Two Sigma Advisers
New York
$1.48M +$503K +433,314 +51%
D.E. Shaw & Co
13
D.E. Shaw & Co
New York
$1.39M +$92.6K +79,847 +7%
GCP
14
GSA Capital Partners
United Kingdom
$1.32M +$686K +591,400 +109%
Morgan Stanley
15
Morgan Stanley
New York
$1.27M +$4.28K +3,693 +0.3%
Two Sigma Investments
16
Two Sigma Investments
New York
$1.27M +$631K +543,719 +99%
Primecap Management
17
Primecap Management
California
$1.19M -$275K -237,000 -19%
Balyasny Asset Management
18
Balyasny Asset Management
Illinois
$1.13M +$1.13M +970,862 New
P
19
Pfizer
New York
$1.11M – – –
Goldman Sachs
20
Goldman Sachs
New York
$1,000K +$470K +405,374 +89%
Jacobs Levy Equity Management
21
Jacobs Levy Equity Management
New Jersey
$995K +$590K +508,617 +146%
Bank of America
22
Bank of America
North Carolina
$827K -$483K -416,777 -37%
Jane Street
23
Jane Street
New York
$770K +$598K +515,257 +346%
Geode Capital Management
24
Geode Capital Management
Massachusetts
$717K -$856K -737,502 -54%
PLC
25
Peapod Lane Capital
New York
$649K +$922 +795 +0.1%
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