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Zentalis Pharmaceuticals
ZNTL

Overview Fund Activity

132 hedge funds and large institutions have $92.9M invested in Zentalis Pharmaceuticals in 2025 Q1 according to their latest regulatory filings, with 18 funds opening new positions, 42 increasing their positions, 49 reducing their positions, and 27 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
132
Holders Change
-10
Holders Change %
-7.04%
% of All Funds
1.79%
Holding in Top 10
2
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+100%
% of All Funds
0.03%
New
18
Increased
42
Reduced
49
Closed
27
Calls
$31K
Puts
$188K
Net Calls
-$157K
Net Calls Change
-$164K

Top Buyers

1
Millennium Management
Millennium Management
New York
+$3.36M
2
Acadian Asset Management
Acadian Asset Management
Massachusetts
+$2.55M
3
TCM
Tang Capital Management
California
+$2.39M
4
Bank of America
Bank of America
North Carolina
+$1.45M
5
PLC
Peapod Lane Capital
New York
+$888K

Top Sellers

1
EAM
Eventide Asset Management
Massachusetts
-$13.6M
2
Citadel Advisors
Citadel Advisors
Florida
-$5M
3
MB
MPM BioImpact
Massachusetts
-$3.35M
4
IHAM
Integral Health Asset Management
New York
-$3.18M
5
Verition Fund Management
Verition Fund Management
Connecticut
-$1.74M
Name Holding Trade Value Shares
Change 		Shares
Change %
MCMC
1
Matrix Capital Management Company
New Hampshire
$22.2M – – –
BlackRock
2
BlackRock
New York
$6.72M -$13.7K -8,592 -0.2%
Vanguard Group
3
Vanguard Group
Pennsylvania
$5.18M -$16.9K -10,628 -0.3%
Millennium Management
4
Millennium Management
New York
$4.88M +$3.36M +2,111,951 +221%
Acadian Asset Management
5
Acadian Asset Management
Massachusetts
$4.24M +$2.55M +1,606,802 +151%
DC
6
Decheng Capital
California
$3.21M -$506K -318,333 -14%
OM
7
Opaleye Management
Massachusetts
$3.16M +$346K +217,500 +12%
AC
8
Almitas Capital
California
$2.72M +$134K +84,025 +5%
TCM
9
Tang Capital Management
California
$2.39M +$2.39M +1,500,000 New
Geode Capital Management
10
Geode Capital Management
Massachusetts
$2.16M +$67.9K +42,705 +3%
State Street
11
State Street
Massachusetts
$2.1M +$49K +30,800 +2%
Primecap Management
12
Primecap Management
California
$2.01M -$407K -256,010 -17%
Bank of America
13
Bank of America
North Carolina
$1.8M +$1.45M +914,093 +423%
D.E. Shaw & Co
14
D.E. Shaw & Co
New York
$1.78M -$193K -121,682 -10%
Morgan Stanley
15
Morgan Stanley
New York
$1.74M -$985K -619,230 -36%
TCM
16
Tybourne Capital Management
Hong Kong
$1.53M – – –
P
17
Pfizer
New York
$1.52M – – –
Two Sigma Advisers
18
Two Sigma Advisers
New York
$1.34M -$74.9K -47,100 -5%
Renaissance Technologies
19
Renaissance Technologies
New York
$1.31M +$456K +286,696 +53%
Federated Hermes
20
Federated Hermes
Pennsylvania
$1.2M +$411K +258,535 +52%
JPMorgan Chase & Co
21
JPMorgan Chase & Co
New York
$1.19M -$180K -113,234 -13%
AQR Capital Management
22
AQR Capital Management
Connecticut
$985K +$630K +396,233 +178%
PLC
23
Peapod Lane Capital
New York
$888K +$888K +558,418 New
Two Sigma Investments
24
Two Sigma Investments
New York
$873K -$107K -67,466 -11%
GCP
25
GSA Capital Partners
United Kingdom
$862K +$633K +397,805 +276%
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