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Zentalis Pharmaceuticals

117 hedge funds and large institutions have $64.5M invested in Zentalis Pharmaceuticals in 2025 Q2 according to their latest regulatory filings, with 22 funds opening new positions, 34 increasing their positions, 44 reducing their positions, and 37 closing their positions.

New
Increased
Maintained
Reduced
Closed

0% more funds holding in top 10

Funds holding in top 10: 22 (0)

4.12% less ownership

Funds ownership: 81.4%77.28% (-4.1%)

11% less funds holding

Funds holding: 132117 (-15)

23% less repeat investments, than reductions

Existing positions increased: 34 | Existing positions reduced: 44

31% less capital invested

Capital invested by funds: $92.9M → $64.5M (-$28.4M)

41% less first-time investments, than exits

New positions opened: 22 | Existing positions closed: 37

100% less call options, than puts

Call options by funds: $0 | Put options by funds: $73K

Holders
117
Holders Change
-15
Holders Change %
-11.36%
% of All Funds
1.54%
Holding in Top 10
2
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.03%
New
22
Increased
34
Reduced
44
Closed
37
Calls
Puts
$73K
Net Calls
-$73K
Net Calls Change
+$84K
Name Holding Trade Value Shares
Change
Change in
Stake
JP Morgan Chase
26
JP Morgan Chase
New York
$639K -$259K -196,029 -26%
WP
27
Woodline Partners
California
$615K
5VM
28
5AM Venture Management
California
$568K
Citadel Advisors
29
Citadel Advisors
Florida
$536K +$516K +391,282 +551%
AQR Capital Management
30
AQR Capital Management
Connecticut
$505K -$243K -184,372 -30%
Man Group
31
Man Group
United Kingdom
$471K +$403K +305,328 +302%
Dimensional Fund Advisors
32
Dimensional Fund Advisors
Texas
$390K -$147K -111,434 -25%
CSS
33
Cubist Systematic Strategies
Connecticut
$372K +$319K +242,106 +310%
Connor, Clark & Lunn Investment Management (CC&L)
34
Connor, Clark & Lunn Investment Management (CC&L)
British Columbia, Canada
$365K -$61.2K -46,391 -13%
Charles Schwab
35
Charles Schwab
California
$347K -$247K -187,402 -39%
State Street
36
State Street
Massachusetts
$315K -$1.38M -1,047,995 -79%
XT
37
XTX Topco
Cayman Islands
$307K +$185K +140,433 +113%
Wealth Enhancement Advisory Services
38
Wealth Enhancement Advisory Services
Minnesota
$219K -$79.2K -60,065 -26%
Fidelity Investments
39
Fidelity Investments
Massachusetts
$214K +$3.28K +2,487 +1%
BNP Paribas Financial Markets
40
BNP Paribas Financial Markets
France
$201K +$135K +102,661 +145%
SEI Investments
41
SEI Investments
Pennsylvania
$194K -$46.6K -35,320 -17%
Invesco
42
Invesco
Georgia
$181K +$8.22K +6,230 +4%
Russell Investments Group
43
Russell Investments Group
United Kingdom
$175K -$1.67K -1,265 -0.8%
Susquehanna International Group
44
Susquehanna International Group
Pennsylvania
$169K +$52.9K +40,082 +38%
Walleye Capital
45
Walleye Capital
New York
$151K -$279K -211,521 -62%
UBS Group
46
UBS Group
Switzerland
$150K -$16.4K -12,468 -9%
Northern Trust
47
Northern Trust
Illinois
$143K -$447K -338,859 -73%
HF
48
HRT Financial
New York
$132K +$150K +113,863 New
SCM
49
Stonepine Capital Management
Oregon
$126K +$64.6K +49,010 +82%
QL
50
Quarry LP
New York
$122K -$19.8K -15,000 -13%

ZNTL Hedge Fund Activity: Q2 2025 in Review

117 of the 7,596 institutional investors tracked by Wall St. Rank reported a position in Zentalis Pharmaceuticals (ZNTL) for Q2 2025, worth a combined $64.5M — down 31% from $92.9M a quarter earlier.

Sellers outnumbered buyers: 37 funds closed out of ZNTL and 22 opened new positions — a net loss of 15 holders — while 44 trimmed existing stakes and 34 added.

The largest buyer was Balyasny Asset Management, opening a new position worth an estimated $1.28M. The largest seller was BlackRock, cutting an estimated $3.28M.

  • 117 institutional investors held Zentalis Pharmaceuticals (ZNTL) as of Q2 2025, down from 132 in Q1 2025.
  • Funds reported $64.5M of Zentalis Pharmaceuticals stock for Q2 2025, down 31% quarter-over-quarter.
  • 22 funds opened new Zentalis Pharmaceuticals positions in Q2 2025 and 37 closed out, a net change of -15 holders.
  • The largest Zentalis Pharmaceuticals buyer in Q2 2025 was Balyasny Asset Management, an estimated $1.28M added.
  • The largest Zentalis Pharmaceuticals seller in Q2 2025 was BlackRock, an estimated $3.28M sold.

Based on aggregated 13F filings for Q2 2025.