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Zai Lab

138 hedge funds and large institutions have $1.19B invested in Zai Lab in 2025 Q3 according to their latest regulatory filings, with 21 funds opening new positions, 48 increasing their positions, 46 reducing their positions, and 38 closing their positions.

New
Increased
Maintained
Reduced
Closed

20% more funds holding in top 10

Funds holding in top 10: 56 (+1)

4% more repeat investments, than reductions

Existing positions increased: 48 | Existing positions reduced: 46

7% less call options, than puts

Call options by funds: $7.24M | Put options by funds: $7.79M

6.9% less ownership

Funds ownership: 38.36%31.47% (-6.9%)

12% less funds holding

Funds holding: 156138 (-18)

20% less capital invested

Capital invested by funds: $1.49B → $1.19B (-$298M)

45% less first-time investments, than exits

New positions opened: 21 | Existing positions closed: 38

Holders
138
Holders Change
-18
Holders Change %
-11.54%
% of All Funds
1.81%
Holding in Top 10
6
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+20%
% of All Funds
0.08%
New
21
Increased
48
Reduced
46
Closed
38
Calls
$7.24M
Puts
$7.79M
Net Calls
-$551K
Net Calls Change
+$657K
Name Holding Trade Value Shares
Change
Change in
Stake
JF
151
Jump Financial
Illinois
-$2.31M -66,003 Closed
Axa
152
Axa
France
-$2.3M -65,814 Closed
Two Sigma Advisers
153
Two Sigma Advisers
New York
-$2.1M -60,100 Closed
SSA
154
Schonfeld Strategic Advisors
New York
-$1.97M -56,473 Closed
KI
155
Keystone Investors
Singapore
-$1.93M -55,210 Closed
Ohio Public Employees Retirement System (OPERS)
156
Ohio Public Employees Retirement System (OPERS)
Ohio
-$833K -23,820 Closed
AIMCA
157
Alberta Investment Management Corp (AIMCo)
Alberta, Canada
-$769K -22,000 Closed
M&T Bank
158
M&T Bank
New York
-$763K -21,825 Closed
PCM
159
Penserra Capital Management
California
-$733K -20,978 Closed
Walleye Capital
160
Walleye Capital
New York
-$488K -13,949 Closed
NPT
161
National Philanthropic Trust
Pennsylvania
-$350K -10,000 Closed
WA
162
Wealth Alliance
New York
-$204K -5,821 Closed
UBS AM
163
UBS AM
Illinois
-$184K -5,250 Closed
DP
164
Diadema Partners
New Jersey
-$13.2K -3,785 Closed
Lazard Asset Management
165
Lazard Asset Management
New York
-$73K -2,092 Closed
PAP
166
Persistent Asset Partners
Hong Kong
-$30.5K -873 Closed
T. Rowe Price Investment Management
167
T. Rowe Price Investment Management
Maryland
-$25K -713 Closed
ST
168
Smithfield Trust
Pennsylvania
-$19K -531 Closed
PHK
169
Point72 Hong Kong
Hong Kong
-$14K -400 Closed
WTC
170
WhitTier Trust Company
Nevada
-$11.3K -322 Closed
CIAM
171
Caitong International Asset Management
Hong Kong
-$3.99K -114 Closed
RAM
172
Riggs Asset Management
Pennsylvania
-$2.66K -76 Closed
SO
173
Sierra Ocean
California
-$2.45K -70 Closed
BBHC
174
Brown Brothers Harriman & Co
New York
-$1.4K -40 Closed
BIG
175
Brooklyn Investment Group
New York
-$1.01K -29 Closed

ZLAB Hedge Fund Activity: Q3 2025 in Review

138 of the 7,620 institutional investors tracked by Wall St. Rank reported a position in Zai Lab (ZLAB) for Q3 2025, worth a combined $1.19B — down 20% from $1.49B a quarter earlier.

Sellers outnumbered buyers: 38 funds closed out of ZLAB and 21 opened new positions — a net loss of 17 holders — while 46 trimmed existing stakes and 48 added.

The largest buyer was T. Rowe Price Associates, adding an estimated $27.4M. The largest seller was RTW Investments, cutting an estimated $112M.

  • 138 institutional investors held Zai Lab (ZLAB) as of Q3 2025, down from 156 in Q2 2025.
  • Funds reported $1.19B of Zai Lab stock for Q3 2025, down 20% quarter-over-quarter.
  • 21 funds opened new Zai Lab positions in Q3 2025 and 38 closed out, a net change of -17 holders.
  • The largest Zai Lab buyer in Q3 2025 was T. Rowe Price Associates, an estimated $27.4M added.
  • The largest Zai Lab seller in Q3 2025 was RTW Investments, an estimated $112M sold.

Based on aggregated 13F filings for Q3 2025.