Two Sigma Advisers
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Two Sigma Advisers’s Zai Lab ZLAB Stock Holding History

Two Sigma Advisers’s Portfolio ZLAB Stock Details ZLAB Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2025
Q3 		– Sell
-60,100
Closed -$2.1M – 2679
2025
Q2 		$2.1M Buy
60,100
+21,900
+57% +$720K ﹤0.01% 1094
2025
Q1 		$1.38M Buy
38,200
+20,000
+110% +$615K ﹤0.01% 1311
2024
Q4 		$477K Buy
18,200
+4,200
+30% +$117K ﹤0.01% 1793
2024
Q3 		$338K Buy
+14,000
New +$265K ﹤0.01% 1864
2022
Q2 		– Sell
-41,300
Closed -$1.82M – 2908
2022
Q1 		$1.82M Sell
41,300
-78,000
-65% -$3.77M ﹤0.01% 1318
2021
Q4 		$7.5M Buy
119,300
+104,300
+695% +$8.84M 0.02% 604
2021
Q3 		$1.58M Buy
15,000
+13,400
+838% +$1.92M ﹤0.01% 1379
2021
Q2 		$283K Sell
1,600
-10,500
-87% -$1.69M ﹤0.01% 2157
2021
Q1 		$1.61M Buy
12,100
+4,900
+68% +$759K ﹤0.01% 1379
2020
Q4 		$974K Buy
+7,200
New +$733K ﹤0.01% 1578
2020
Q3 		– Sell
-10,225
Closed -$840K – 2660
2020
Q2 		$840K Buy
+10,225
New +$692K ﹤0.01% 1664

Other funds holding ZLAB

Capital World Investors
Capital World Investors Los Angeles, California $733B AUM 35.63% 1-Year Est. Return
Fidelity Investments
Fidelity Investments Boston, Massachusetts $1.9T AUM 41.92% 1-Year Est. Return
ClearBridge Investments
ClearBridge Investments New York $115B AUM 24.78% 1-Year Est. Return
RI
RTW Investments New York $10B AUM 135.35% 1-Year Est. Return
Janus Henderson Group
Janus Henderson Group London, United Kingdom $209B AUM 37.72% 1-Year Est. Return
Wellington Management Group
Wellington Management Group Boston, Massachusetts $535B AUM 26.23% 1-Year Est. Return
FLSM
Frazier Life Sciences Management Palo Alto, California $3.89B AUM 201.1% 1-Year Est. Return
BAMCO Inc
BAMCO Inc New York $33.1B AUM 11.16% 1-Year Est. Return
Citadel Advisors
Citadel Advisors Miami, Florida $618B AUM 30.34% 1-Year Est. Return
T. Rowe Price Associates
T. Rowe Price Associates Baltimore, Maryland $865B AUM 30.76% 1-Year Est. Return

Two Sigma Advisers's ZLAB Position: Q3 2025 in Review

Two Sigma Advisers sold out of Zai Lab (ZLAB) in Q3 2025, closing a stake of 60,100 shares — an estimated $2.1M sold.

Two Sigma Advisers first reported a position in ZLAB in Q2 2020 and held it in 11 quarters. The position peaked at $7.5M in Q4 2021. 138 funds tracked by Wall St. Rank hold ZLAB as of Q3 2025.

  • Two Sigma Advisers reported no remaining Zai Lab position as of Q3 2025 after selling out during the quarter.
  • Two Sigma Advisers sold 60,100 Zai Lab shares in Q3 2025, an estimated $2.1M.
  • Two Sigma Advisers first reported a position in Zai Lab in Q2 2020 and held it in 11 quarters.
  • Two Sigma Advisers's Zai Lab position peaked at $7.5M in Q4 2021.
  • 138 funds tracked by Wall St. Rank held Zai Lab as of Q3 2025.

Based on Two Sigma Advisers's 13F filing for Q3 2025, filed 14 Nov 2025.