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Zai Lab

138 hedge funds and large institutions have $1.19B invested in Zai Lab in 2025 Q3 according to their latest regulatory filings, with 21 funds opening new positions, 48 increasing their positions, 46 reducing their positions, and 38 closing their positions.

New
Increased
Maintained
Reduced
Closed

20% more funds holding in top 10

Funds holding in top 10: 56 (+1)

4% more repeat investments, than reductions

Existing positions increased: 48 | Existing positions reduced: 46

7% less call options, than puts

Call options by funds: $7.24M | Put options by funds: $7.79M

6.9% less ownership

Funds ownership: 38.36%31.47% (-6.9%)

12% less funds holding

Funds holding: 156138 (-18)

20% less capital invested

Capital invested by funds: $1.49B → $1.19B (-$298M)

45% less first-time investments, than exits

New positions opened: 21 | Existing positions closed: 38

Holders
138
Holders Change
-18
Holders Change %
-11.54%
% of All Funds
1.81%
Holding in Top 10
6
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+20%
% of All Funds
0.08%
New
21
Increased
48
Reduced
46
Closed
38
Calls
$7.24M
Puts
$7.79M
Net Calls
-$551K
Net Calls Change
+$657K
Name Holding Trade Value Shares
Change
Change in
Stake
Capital World Investors
1
Capital World Investors
California
$206M +$1.43M +41,481 +0.7%
Fidelity Investments
2
Fidelity Investments
Massachusetts
$159M -$51.5M -1,495,712 -24%
ClearBridge Investments
3
ClearBridge Investments
New York
$119M -$17M -492,619 -12%
RI
4
RTW Investments
New York
$77.7M -$112M -3,245,504 -59%
Janus Henderson Group
5
Janus Henderson Group
United Kingdom
$69.5M -$5.11M -148,323 -7%
Wellington Management Group
6
Wellington Management Group
Massachusetts
$58.2M +$11.8M +341,492 +25%
FLSM
7
Frazier Life Sciences Management
California
$55.1M +$11M +319,182 +24%
BAMCO Inc
8
BAMCO Inc
New York
$46.5M -$7.46M -216,571 -14%
Citadel Advisors
9
Citadel Advisors
Florida
$33.5M +$21.4M +620,830 +170%
T. Rowe Price Associates
10
T. Rowe Price Associates
Maryland
$32.2M +$27.4M +795,634 +520%
ACM
11
ADAR1 Capital Management
Texas
$29.4M +$632K +18,343 +2%
Allianz Asset Management
12
Allianz Asset Management
Germany
$27.6M -$4.03M -117,000 -13%
RSCM
13
Rock Springs Capital Management
Maryland
$26.8M -$2.76M -80,199 -9%
MB
14
MPM BioImpact
Massachusetts
$25.3M
CWG
15
C WorldWide Group
Denmark
$17.3M
BlackRock
16
BlackRock
New York
$16M +$629K +18,276 +4%
BGI
17
B Group Inc
Texas
$13.6M
Legal & General Group
18
Legal & General Group
United Kingdom
$13M +$10.3M +300,623 +367%
UBS Group
19
UBS Group
Switzerland
$10.4M +$2.23M +64,904 +27%
NFT
20
Nan Fung Trinity
Hong Kong
$9.15M
Envestnet Asset Management
21
Envestnet Asset Management
Illinois
$8.54M +$440K +12,783 +5%
SCM
22
Superstring Capital Management
New York
$6.8M +$2.26M +65,733 +49%
WP
23
Woodline Partners
California
$6.73M -$34.5M -1,002,507 -83%
Raymond James Financial
24
Raymond James Financial
Florida
$6.26M -$177K -5,147 -3%
Wells Fargo
25
Wells Fargo
California
$5.94M +$22.4K +652 +0.4%

ZLAB Hedge Fund Activity: Q3 2025 in Review

138 of the 7,619 institutional investors tracked by Wall St. Rank reported a position in Zai Lab (ZLAB) for Q3 2025, worth a combined $1.19B — down 20% from $1.49B a quarter earlier.

Sellers outnumbered buyers: 38 funds closed out of ZLAB and 21 opened new positions — a net loss of 17 holders — while 46 trimmed existing stakes and 48 added.

The largest buyer was T. Rowe Price Associates, adding an estimated $27.4M. The largest seller was RTW Investments, cutting an estimated $112M.

  • 138 institutional investors held Zai Lab (ZLAB) as of Q3 2025, down from 156 in Q2 2025.
  • Funds reported $1.19B of Zai Lab stock for Q3 2025, down 20% quarter-over-quarter.
  • 21 funds opened new Zai Lab positions in Q3 2025 and 38 closed out, a net change of -17 holders.
  • The largest Zai Lab buyer in Q3 2025 was T. Rowe Price Associates, an estimated $27.4M added.
  • The largest Zai Lab seller in Q3 2025 was RTW Investments, an estimated $112M sold.

Based on aggregated 13F filings for Q3 2025.