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Zai Lab

126 hedge funds and large institutions have $511M invested in Zai Lab in 2025 Q4 according to their latest regulatory filings, with 33 funds opening new positions, 36 increasing their positions, 40 reducing their positions, and 44 closing their positions.

New
Increased
Maintained
Reduced
Closed

5.62% less ownership

Funds ownership: 31.47%25.85% (-5.6%)

9% less funds holding

Funds holding: 138126 (-12)

10% less repeat investments, than reductions

Existing positions increased: 36 | Existing positions reduced: 40

25% less first-time investments, than exits

New positions opened: 33 | Existing positions closed: 44

57% less capital invested

Capital invested by funds: $1.19B → $511M (-$681M)

67% less funds holding in top 10

Funds holding in top 10: 62 (-4)

94% less call options, than puts

Call options by funds: $395K | Put options by funds: $6.48M

Holders
126
Holders Change
-12
Holders Change %
-8.7%
% of All Funds
1.53%
Holding in Top 10
2
Holding in Top 10 Change
-4
Holding in Top 10 Change %
-66.67%
% of All Funds
0.02%
New
33
Increased
36
Reduced
40
Closed
44
Calls
$395K
Puts
$6.48M
Net Calls
-$6.09M
Net Calls Change
-$5.54M
Name Holding Trade Value Shares
Change
Change in
Stake
RI
1
RTW Investments
New York
$123M +$109M +4,667,660 +204%
FLSM
2
Frazier Life Sciences Management
California
$33.6M +$6.44M +275,000 +17%
ClearBridge Investments
3
ClearBridge Investments
New York
$31.9M -$40.1M -1,711,302 -49%
UBS Group
4
UBS Group
Switzerland
$31.4M +$34.5M +1,475,698 +481%
Citadel Advisors
5
Citadel Advisors
Florida
$29.8M +$16.4M +700,803 +71%
Fidelity Investments
6
Fidelity Investments
Massachusetts
$25.4M -$76.4M -3,261,305 -69%
BAMCO Inc
7
BAMCO Inc
New York
$25M +$1.09M +46,762 +3%
ACM
8
ADAR1 Capital Management
Texas
$22M +$8.84M +377,740 +43%
RSCM
9
Rock Springs Capital Management
Maryland
$14.3M +$476K +20,353 +3%
Wellington Management Group
10
Wellington Management Group
Massachusetts
$13.3M -$22.6M -965,597 -56%
BlackRock
11
BlackRock
New York
$11.2M +$3.78M +161,650 +34%
T. Rowe Price Associates
12
T. Rowe Price Associates
Maryland
$10.6M -$8.09M -345,717 -36%
CWG
13
C WorldWide Group
Denmark
$9M
BGI
14
B Group Inc
Texas
$7.06M
Bank of America
15
Bank of America
North Carolina
$6.86M +$5.77M +246,395 +173%
Legal & General Group
16
Legal & General Group
United Kingdom
$6.84M +$125K +5,341 +1%
Jane Street
17
Jane Street
New York
$6.74M +$8.94M +382,062 New
Walleye Capital
18
Walleye Capital
New York
$6.59M +$8.74M +373,399 New
Schroder Investment Management Group
19
Schroder Investment Management Group
United Kingdom
$5.29M +$3.34M +142,783 +91%
JP Morgan Chase
20
JP Morgan Chase
New York
$5.18M +$6.66M +284,296 +3,022%
Morgan Stanley
21
Morgan Stanley
New York
$5.11M +$3.98M +169,825 +142%
NFT
22
Nan Fung Trinity
Hong Kong
$4.76M
D.E. Shaw & Co
23
D.E. Shaw & Co
New York
$4.21M +$4.78M +204,319 +596%
Marshall Wace
24
Marshall Wace
United Kingdom
$4.09M +$3.99M +170,400 +278%
HWAM
25
Hennion & Walsh Asset Management
New Jersey
$3.62M +$1.05M +44,945 +28%