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X4 Pharmaceuticals

42 hedge funds and large institutions have $55.3M invested in X4 Pharmaceuticals in 2025 Q3 according to their latest regulatory filings, with 11 funds opening new positions, 11 increasing their positions, 10 reducing their positions, and 20 closing their positions.

New
Increased
Maintained
Reduced
Closed

1,403% more call options, than puts

Call options by funds: $1.1M | Put options by funds: $73K

937% more capital invested

Capital invested by funds: $5.33M → $55.3M (+$49.9M)

23.54% more ownership

Funds ownership: 48.44%71.98% (+24%)

10% more repeat investments, than reductions

Existing positions increased: 11 | Existing positions reduced: 10

18% less funds holding

Funds holding: 5142 (-9)

45% less first-time investments, than exits

New positions opened: 11 | Existing positions closed: 20

Holders
42
Holders Change
-9
Holders Change %
-17.65%
% of All Funds
0.55%
Holding in Top 10
1
Holding in Top 10 Change
+1
Holding in Top 10 Change %
% of All Funds
0.01%
New
11
Increased
11
Reduced
10
Closed
20
Calls
$1.1M
Puts
$73K
Net Calls
+$1.02M
Net Calls Change
+$326K
Name Holding Trade Value Shares
Change
Change in
Stake
BCLSI
1
Bain Capital Life Sciences Investors
Massachusetts
$8.33M +$4.83M +1,872,729 +332%
NMC
2
NEA Management Company
Maryland
$7.64M +$4.47M +1,734,184 +347%
BI
3
BVF Inc
California
$7.64M +$5.76M +2,233,742 New
NCM
4
Nantahala Capital Management
Connecticut
$7.62M +$5.75M +2,228,350 New
RA
5
Rosalind Advisors
Ontario, Canada
$5.28M +$3.98M +1,544,607 New
DTC
6
Deep Track Capital
Connecticut
$3.84M +$2.89M +1,122,484 New
SCM
7
Stonepine Capital Management
Oregon
$3.61M +$2.72M +1,056,338 New
KCM
8
Kingdon Capital Management
New York
$3.19M +$1.81M +700,000 +300%
SC
9
Stempoint Capital
New York
$1.9M +$1.43M +555,411 New
Vanguard Group
10
Vanguard Group
Pennsylvania
$1.4M +$461K +178,593 +77%
BFM
11
Boothbay Fund Management
New York
$1.18M +$887K +343,963 New
ACA
12
Acorn Capital Advisors
New York
$935K +$308K +119,619 +78%
PFCS
13
Pale Fire Capital SE
Czech Republic
$619K +$312K +120,800 +201%
UBS Group
14
UBS Group
Switzerland
$547K +$129K +49,876 +45%
PWM
15
Palumbo Wealth Management
New York
$326K +$246K +95,327 New
Geode Capital Management
16
Geode Capital Management
Massachusetts
$272K +$78.7K +30,512 +62%
Millennium Management
17
Millennium Management
New York
$222K -$34.2K -13,266 -17%
BlackRock
18
BlackRock
New York
$212K -$302K -117,294 -65%
State Street
19
State Street
Massachusetts
$132K +$59.8K +23,200 +149%
Point72 Asset Management
20
Point72 Asset Management
Connecticut
$74.1K -$3 -1 -0%
Bank of America
21
Bank of America
North Carolina
$66K -$157K -61,012 -76%
Renaissance Technologies
22
Renaissance Technologies
New York
$65.6K +$4.67K +1,811 +10%
Two Sigma Investments
23
Two Sigma Investments
New York
$47.4K +$35.8K +13,868 New
TRCT
24
Tower Research Capital (TRC)
New York
$36.5K +$14.1K +5,476 +105%
Group One Trading
25
Group One Trading
Illinois
$13.7K

XFOR Hedge Fund Activity: Q3 2025 in Review

42 of the 7,621 institutional investors tracked by Wall St. Rank reported a position in X4 Pharmaceuticals (XFOR) for Q3 2025, worth a combined $55.3M — up 937% from $5.33M a quarter earlier.

Sellers outnumbered buyers: 20 funds closed out of XFOR and 11 opened new positions — a net loss of 9 holders — while 10 trimmed existing stakes and 11 added.

The largest buyer was BVF Inc, opening a new position worth an estimated $5.76M. The largest seller was BlackRock, cutting an estimated $302K.

  • 42 institutional investors held X4 Pharmaceuticals (XFOR) as of Q3 2025, down from 51 in Q2 2025.
  • Funds reported $55.3M of X4 Pharmaceuticals stock for Q3 2025, up 937% quarter-over-quarter.
  • 11 funds opened new X4 Pharmaceuticals positions in Q3 2025 and 20 closed out, a net change of -9 holders.
  • The largest X4 Pharmaceuticals buyer in Q3 2025 was BVF Inc, an estimated $5.76M added.
  • The largest X4 Pharmaceuticals seller in Q3 2025 was BlackRock, an estimated $302K sold.

Based on aggregated 13F filings for Q3 2025.