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X4 Pharmaceuticals

51 hedge funds and large institutions have $5.33M invested in X4 Pharmaceuticals in 2025 Q2 according to their latest regulatory filings, with 10 funds opening new positions, 16 increasing their positions, 17 reducing their positions, and 52 closing their positions.

New
Increased
Maintained
Reduced
Closed

1,745% more call options, than puts

Call options by funds: $738K | Put options by funds: $40K

46.55% more ownership

Funds ownership: 1.89%48.44% (+47%)

6% less repeat investments, than reductions

Existing positions increased: 16 | Existing positions reduced: 17

45% less funds holding

Funds holding: 9351 (-42)

77% less capital invested

Capital invested by funds: $23.6M → $5.33M (-$18.2M)

81% less first-time investments, than exits

New positions opened: 10 | Existing positions closed: 52

Holders
51
Holders Change
-42
Holders Change %
-45.16%
% of All Funds
0.67%
Holding in Top 10
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
10
Increased
16
Reduced
17
Closed
52
Calls
$738K
Puts
$40K
Net Calls
+$698K
Net Calls Change
+$527K
Name Holding Trade Value Shares
Change
Change in
Stake
BCLSI
1
Bain Capital Life Sciences Investors
Massachusetts
$1.07M
NMC
2
NEA Management Company
Maryland
$949K -$4 -1 -0%
KCM
3
Kingdon Capital Management
New York
$443K -$4 -1 -0%
Vanguard Group
4
Vanguard Group
Pennsylvania
$441K -$152K -37,025 -14%
BlackRock
5
BlackRock
New York
$341K -$826K -201,782 -53%
ACA
6
Acorn Capital Advisors
New York
$292K -$368K -89,958 -37%
GCP
7
GSA Capital Partners
United Kingdom
$252K +$543K +132,724 New
UBS Group
8
UBS Group
Switzerland
$209K -$237K -57,947 -35%
Jane Street
9
Jane Street
New York
$185K +$398K +97,344 New
Bank of America
10
Bank of America
North Carolina
$153K +$318K +77,738 +3,015%
UOC
11
UBS O'Connor
Illinois
$152K +$293K +71,580 +850%
Millennium Management
12
Millennium Management
New York
$148K +$284K +69,436 +805%
PFCS
13
Pale Fire Capital SE
Czech Republic
$114K -$31.9K -7,794 -11%
Geode Capital Management
14
Geode Capital Management
Massachusetts
$93.4K -$293K -71,510 -59%
Squarepoint
15
Squarepoint
New York
$74.1K +$160K +38,982 New
Susquehanna International Group
16
Susquehanna International Group
Pennsylvania
$66.2K -$91.1K -22,258 -39%
AQR Capital Management
17
AQR Capital Management
Connecticut
$50.1K +$96.1K +23,483 +810%
Point72 Asset Management
18
Point72 Asset Management
Connecticut
$41.2K
Goldman Sachs
19
Goldman Sachs
New York
$35.8K +$39.8K +9,735 +107%
Renaissance Technologies
20
Renaissance Technologies
New York
$33K +$68.3K +16,696 +2,492%
State Street
21
State Street
Massachusetts
$29.5K -$353K -86,302 -85%
VF
22
Virtu Financial
New York
$24K +$42.3K +10,343 +461%
SSA
23
Schonfeld Strategic Advisors
New York
$21.4K +$327 +80 +0.7%
Morgan Stanley
24
Morgan Stanley
New York
$20.8K -$33.1K -8,076 -43%
HF
25
HRT Financial
New York
$20K +$38.5K +9,399 +818%

XFOR Hedge Fund Activity: Q2 2025 in Review

51 of the 7,595 institutional investors tracked by Wall St. Rank reported a position in X4 Pharmaceuticals (XFOR) for Q2 2025, worth a combined $5.33M — down 77% from $23.6M a quarter earlier.

Sellers outnumbered buyers: 52 funds closed out of XFOR and 10 opened new positions — a net loss of 42 holders — while 17 trimmed existing stakes and 16 added.

The largest buyer was GSA Capital Partners, opening a new position worth an estimated $543K. The largest seller was OrbiMed, exiting entirely with an estimated $1.6M sold.

  • 51 institutional investors held X4 Pharmaceuticals (XFOR) as of Q2 2025, down from 93 in Q1 2025.
  • Funds reported $5.33M of X4 Pharmaceuticals stock for Q2 2025, down 77% quarter-over-quarter.
  • 10 funds opened new X4 Pharmaceuticals positions in Q2 2025 and 52 closed out, a net change of -42 holders.
  • The largest X4 Pharmaceuticals buyer in Q2 2025 was GSA Capital Partners, an estimated $543K added.
  • The largest X4 Pharmaceuticals seller in Q2 2025 was OrbiMed, an estimated $1.6M sold.

Based on aggregated 13F filings for Q2 2025.