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X4 Pharmaceuticals
XFOR

84 hedge funds and large institutions have $388M invested in X4 Pharmaceuticals in 2026 Q1 according to their latest regulatory filings, with 18 funds opening new positions, 22 increasing their positions, 23 reducing their positions, and 11 closing their positions.

New
Increased
Maintained
Reduced
Closed

64% more first-time investments, than exits

New positions opened: 18 | Existing positions closed: 11

50% more funds holding in top 10

Funds holding in top 10: 4 → 6 (+2)

8% more capital invested

Capital invested by funds: $358M → $388M (+$30.4M)

6% more funds holding

Funds holding: 79 → 84 (+5)

1.01% more ownership

Funds ownership: 102.28% → 103.28% (+1%)

4% less repeat investments, than reductions

Existing positions increased: 22 | Existing positions reduced: 23

Holders
84
Holders Change
+5
Holders Change %
+6.33%
% of All Funds
1.03%
Holding in Top 10
6
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+50%
% of All Funds
0.07%
New
18
Increased
22
Reduced
23
Closed
11
Calls
–
Puts
–
Net Calls
–
Net Calls Change
–

Top Buyers

1
DTC
Deep Track Capital
Connecticut
+$4.97M
2
Morgan Stanley
Morgan Stanley
New York
+$4.72M
3
Millennium Management
Millennium Management
New York
+$4.32M
4
Susquehanna International Group
Susquehanna International Group
Pennsylvania
+$3.12M
5
SVCM
Saturn V Capital Management
Texas
+$2.46M

Top Sellers

1
SL
Siren LLC
Connecticut
-$6M
2
Point72 Asset Management
Point72 Asset Management
Connecticut
-$3.23M
3
Fidelity Investments
Fidelity Investments
Massachusetts
-$1.48M
4
SCM
Silverarc Capital Management
Massachusetts
-$1.43M
5
SCM
Stonepine Capital Management
Oregon
-$967K
Name Holding Trade Value Shares
Change 		Change in
Stake
QCG
76
Quadrant Capital Group
Ohio
$529 +$479 +128 New
PA
77
Parallel Advisors
California
$479 +$435 +116 New
SS
78
SBI Securities
Japan
$223 +$15 +4 +8%
Jones Financial Companies
79
Jones Financial Companies
Missouri
$154 – – –
Rockefeller Capital Management
80
Rockefeller Capital Management
New York
$136 – – –
JP Morgan Chase
81
JP Morgan Chase
New York
$132 -$17K -4,548 -99%
HWM
82
HighMark Wealth Management
Minnesota
$24 – – –
Northwestern Mutual Wealth Management
83
Northwestern Mutual Wealth Management
Wisconsin
$21 – – –
SL
84
Siren LLC
Connecticut
– -$6M -1,500,000 Closed
Point72 Asset Management
85
Point72 Asset Management
Connecticut
– -$3.23M -808,154 Closed
SCM
86
Silverarc Capital Management
Massachusetts
– -$1.43M -357,387 Closed
Citadel Advisors
87
Citadel Advisors
Florida
– -$515K -128,675 Closed
Balyasny Asset Management
88
Balyasny Asset Management
Illinois
– -$258K -64,505 Closed
Man Group
89
Man Group
United Kingdom
– -$96.7K -24,187 Closed
LIP
90
Lighthouse Investment Partners
Florida
– -$88.8K -22,200 Closed
Squarepoint
91
Squarepoint
New York
– -$50.1K -12,518 Closed
FFO
92
Fortitude Family Office
Arizona
– -$548 -137 Closed
NA
93
NewEdge Advisors
Louisiana
– -$132 -33 Closed
RWM
94
RMG Wealth Management
Wisconsin
– -$64 -28 Closed
Royal Bank of Canada
95
Royal Bank of Canada
Ontario, Canada
– +$41 +11 +11%
1 2 3
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XFOR Hedge Fund Activity: Q1 2026 in Review

84 of the 8,126 institutional investors tracked by Wall St. Rank reported a position in X4 Pharmaceuticals (XFOR) for Q1 2026, worth a combined $388M — up 8.5% from $358M a quarter earlier.

Buyers outnumbered sellers: 18 funds opened new XFOR positions and 11 closed out — a net gain of 7 holders — while 22 added to existing stakes and 23 trimmed.

The largest buyer was Deep Track Capital, adding an estimated $4.97M. The largest seller was Siren LLC, exiting entirely with an estimated $6M sold.

  • 84 institutional investors held X4 Pharmaceuticals (XFOR) as of Q1 2026, up from 79 in Q4 2025.
  • Funds reported $388M of X4 Pharmaceuticals stock for Q1 2026, up 8.5% quarter-over-quarter.
  • 18 funds opened new X4 Pharmaceuticals positions in Q1 2026 and 11 closed out, a net change of +7 holders.
  • The largest X4 Pharmaceuticals buyer in Q1 2026 was Deep Track Capital, an estimated $4.97M added.
  • The largest X4 Pharmaceuticals seller in Q1 2026 was Siren LLC, an estimated $6M sold.

Based on aggregated 13F filings for Q1 2026.