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Xenon Pharmaceuticals
XENE

Overview Fund Activity

206 hedge funds and large institutions have $2.58B invested in Xenon Pharmaceuticals in 2025 Q1 according to their latest regulatory filings, with 20 funds opening new positions, 68 increasing their positions, 73 reducing their positions, and 23 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
206
Holders Change
-3
Holders Change %
-1.44%
% of All Funds
2.8%
Holding in Top 10
14
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+7.69%
% of All Funds
0.19%
New
20
Increased
68
Reduced
73
Closed
23
Calls
$14.8M
Puts
$6.93M
Net Calls
+$7.9M
Net Calls Change
+$3.62M

Top Buyers

1
DTC
Deep Track Capital
Connecticut
+$27.9M
2
Fidelity Investments
Fidelity Investments
Massachusetts
+$25.6M
3
LGM
Logos Global Management
California
+$21.8M
4
Capital International Investors
Capital International Investors
California
+$18.2M
5
VPC
Vestal Point Capital
New York
+$16.4M

Top Sellers

1
BBA
Baker Bros. Advisors
New York
-$21.7M
2
T. Rowe Price Investment Management
T. Rowe Price Investment Management
Maryland
-$21.5M
3
FLAM
First Light Asset Management
Minnesota
-$17.9M
4
CC
Commodore Capital
New York
-$13.9M
5
Federated Hermes
Federated Hermes
Pennsylvania
-$10.9M
Name Holding Trade Value Shares
Change 		Shares
Change %
MOACM
101
Mutual of America Capital Management
New York
$1.64M +$1.64M +48,763 New
VOYA Investment Management
102
VOYA Investment Management
Georgia
$1.61M -$481K -14,350 -23%
Skandinaviska Enskilda Banken (SEB)
103
Skandinaviska Enskilda Banken (SEB)
Sweden
$1.59M +$238K +7,081 +18%
NRD
104
Nebula Research & Development
New York
$1.56M +$879K +26,201 +129%
Neuberger Berman Group
105
Neuberger Berman Group
New York
$1.5M -$1.61M -48,109 -52%
Envestnet Asset Management
106
Envestnet Asset Management
Illinois
$1.44M -$149K -4,447 -9%
ECM
107
ExodusPoint Capital Management
New York
$1.41M -$902K -26,884 -39%
AGP
108
Artia Global Partners
Florida
$1.34M – – –
DekaBank Deutsche Girozentrale
109
DekaBank Deutsche Girozentrale
Germany
$1.31M – – –
Prudential Financial
110
Prudential Financial
New Jersey
$1.31M – – –
RPAM
111
Rhenman & Partners Asset Management
Sweden
$1.17M – – –
TA
112
TLS Advisors
Florida
$1.11M – – –
JSSH
113
J. Safra Sarasin Holding
$1.03M +$429K +12,787 +72%
AI
114
Allostery Investments
Connecticut
$1.01M – – –
SFM
115
Sphera Funds Management
Israel
$876K -$872K -26,000 -50%
Ensign Peak Advisors
116
Ensign Peak Advisors
Utah
$875K – – –
NSEDCP
117
NJ State Employees Deferred Compensation Plan
New Jersey
$839K – – –
Natixis Advisors
118
Natixis Advisors
Massachusetts
$806K +$15.3K +456 +2%
ACM
119
Atika Capital Management
New York
$805K -$1.63M -48,600 -67%
RG
120
Rathbones Group
United Kingdom
$794K – – –
SSA
121
Schonfeld Strategic Advisors
New York
$770K +$262K +7,804 +52%
Handelsbanken Fonder
122
Handelsbanken Fonder
Sweden
$762K – – –
CP
123
CenterBook Partners
Connecticut
$745K +$745K +22,211 New
BC
124
Birchview Capital
Vermont
$705K +$369K +11,000 +110%
Stifel Financial
125
Stifel Financial
Missouri
$689K -$5.4K -161 -0.8%
3 4
5
6 7