XENE icon

Xenon Pharmaceuticals

246 hedge funds and large institutions have $3.78B invested in Xenon Pharmaceuticals in 2025 Q4 according to their latest regulatory filings, with 51 funds opening new positions, 81 increasing their positions, 74 reducing their positions, and 22 closing their positions.

New
Increased
Maintained
Reduced
Closed

more first-time investments, than exits

New positions opened: | Existing positions closed:

more funds holding

Funds holding:

more capital invested

Capital invested by funds: $ → $

more repeat investments, than reductions

Existing positions increased: | Existing positions reduced:

0% more funds holding in top 10

Funds holding in top 10: 99 (0)

0.06% less ownership

Funds ownership: 109.36%109.29% (-0.06%)

34% less call options, than puts

Call options by funds: $36.4M | Put options by funds: $54.7M

Holders
246
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
9
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$36.4M
Puts
$54.7M
Net Calls
Net Calls Change

Top Buyers

1 +$48.5M
2 +$34.5M
3 +$20.6M
4
Federated Hermes
Federated Hermes
Pennsylvania
+$18.5M
5
Two Sigma Investments
Two Sigma Investments
New York
+$18.3M

Top Sellers

1 -$74.8M
2 -$37.8M
3 -$35M
4
Millennium Management
Millennium Management
New York
-$31.5M
5
Holocene Advisors
Holocene Advisors
New York
-$29.2M
Name Holding Trade Value Shares
Change
Change in
Stake
FCMI
76
Foresite Capital Management IV
California
$7.17M
PHP
77
Parkman Healthcare Partners
Connecticut
$6.91M
Wells Fargo
78
Wells Fargo
California
$6.83M
MCM
79
Moore Capital Management
New York
$6.27M
RPAM
80
Rhenman & Partners Asset Management
Sweden
$6.23M
PSC
81
Patient Square Capital
California
$6.12M
RG
82
Redmile Group
California
$6M
AG
83
Algert Global
California
$5.52M
Assenagon Asset Management
84
Assenagon Asset Management
Luxembourg
$5.34M
MOACM
85
Mutual of America Capital Management
New York
$5.2M
Man Group
86
Man Group
United Kingdom
$5.15M
Swiss National Bank
87
Swiss National Bank
Switzerland
$5.11M
Ameriprise
88
Ameriprise
Minnesota
$4.91M
SCM
89
Squadron Capital Management
Illinois
$4.73M
PAI
90
Palo Alto Investors
California
$4.33M
Verition Fund Management
91
Verition Fund Management
Connecticut
$4.2M
BNP Paribas Financial Markets
92
BNP Paribas Financial Markets
France
$4.19M
GIM
93
Granahan Investment Management
Massachusetts
$4.16M
ACM
94
Atika Capital Management
New York
$4.15M
RhumbLine Advisers
95
RhumbLine Advisers
Massachusetts
$4.04M
Royal Bank of Canada
96
Royal Bank of Canada
Ontario, Canada
$4.02M
Russell Investments Group
97
Russell Investments Group
United Kingdom
$3.86M
Balyasny Asset Management
98
Balyasny Asset Management
Illinois
$3.78M
Raymond James Financial
99
Raymond James Financial
Florida
$3.73M
Schroder Investment Management Group
100
Schroder Investment Management Group
United Kingdom
$3.58M