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Xenon Pharmaceuticals

246 hedge funds and large institutions have $3.78B invested in Xenon Pharmaceuticals in 2025 Q4 according to their latest regulatory filings, with 51 funds opening new positions, 81 increasing their positions, 74 reducing their positions, and 22 closing their positions.

New
Increased
Maintained
Reduced
Closed

132% more first-time investments, than exits

New positions opened: 51 | Existing positions closed: 22

12% more funds holding

Funds holding: 219246 (+27)

12% more capital invested

Capital invested by funds: $3.39B → $3.78B (+$399M)

9% more repeat investments, than reductions

Existing positions increased: 81 | Existing positions reduced: 74

0% more funds holding in top 10

Funds holding in top 10: 99 (0)

0.06% less ownership

Funds ownership: 109.36%109.29% (-0.06%)

34% less call options, than puts

Call options by funds: $36.4M | Put options by funds: $54.7M

Holders
246
Holders Change
+27
Holders Change %
+12.33%
% of All Funds
2.99%
Holding in Top 10
9
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.11%
New
51
Increased
81
Reduced
74
Closed
22
Calls
$36.4M
Puts
$54.7M
Net Calls
-$18.4M
Net Calls Change
-$14.5M
Name Holding Trade Value Shares
Change
Change in
Stake
FCMI
76
Foresite Capital Management IV
California
$7.17M
PHP
77
Parkman Healthcare Partners
Connecticut
$6.91M -$922K -21,953 -12%
Wells Fargo
78
Wells Fargo
California
$6.83M +$1.56M +37,076 +32%
MCM
79
Moore Capital Management
New York
$6.27M
RPAM
80
Rhenman & Partners Asset Management
Sweden
$6.23M +$2.44M +58,000 +72%
PSC
81
Patient Square Capital
California
$6.12M +$5.73M +136,500 New
RG
82
Redmile Group
California
$6M +$5.62M +133,882 New
AG
83
Algert Global
California
$5.52M +$2.9M +68,934 +127%
Assenagon Asset Management
84
Assenagon Asset Management
Luxembourg
$5.34M +$5.01M +119,186 New
MOACM
85
Mutual of America Capital Management
New York
$5.2M +$888K +21,153 +22%
Man Group
86
Man Group
United Kingdom
$5.15M +$3.85M +91,707 +397%
Swiss National Bank
87
Swiss National Bank
Switzerland
$5.11M -$521K -12,400 -10%
Ameriprise
88
Ameriprise
Minnesota
$4.91M +$503K +11,977 +12%
SCM
89
Squadron Capital Management
Illinois
$4.73M +$4.43M +105,551 New
PAI
90
Palo Alto Investors
California
$4.33M +$4.05M +96,519 New
Verition Fund Management
91
Verition Fund Management
Connecticut
$4.2M +$1.54M +36,639 +64%
BNP Paribas Financial Markets
92
BNP Paribas Financial Markets
France
$4.19M -$2.76M -65,776 -41%
GIM
93
Granahan Investment Management
Massachusetts
$4.16M +$223K +5,308 +6%
ACM
94
Atika Capital Management
New York
$4.15M +$2.29M +54,506 +143%
RhumbLine Advisers
95
RhumbLine Advisers
Massachusetts
$4.04M -$699K -16,648 -16%
Royal Bank of Canada
96
Royal Bank of Canada
Ontario, Canada
$4.02M -$1.29M -30,788 -26%
Russell Investments Group
97
Russell Investments Group
United Kingdom
$3.86M +$686K +16,328 +23%
Balyasny Asset Management
98
Balyasny Asset Management
Illinois
$3.78M -$10M -238,096 -74%
Raymond James Financial
99
Raymond James Financial
Florida
$3.73M +$560K +13,333 +19%
Schroder Investment Management Group
100
Schroder Investment Management Group
United Kingdom
$3.58M