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Xenon Pharmaceuticals
XENE

Overview Fund Activity

205 hedge funds and large institutions have $2.6B invested in Xenon Pharmaceuticals in 2025 Q2 according to their latest regulatory filings, with 41 funds opening new positions, 77 increasing their positions, 55 reducing their positions, and 40 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
205
Holders Change
-1
Holders Change %
-0.49%
% of All Funds
2.75%
Holding in Top 10
10
Holding in Top 10 Change
-4
Holding in Top 10 Change %
-28.57%
% of All Funds
0.13%
New
41
Increased
77
Reduced
55
Closed
40
Calls
$11.4M
Puts
$9.75M
Net Calls
+$1.67M
Net Calls Change
-$6.22M

Top Buyers

1
BlackRock
BlackRock
New York
$168M
2
Holocene Advisors
Holocene Advisors
New York
$56.6M
3
State Street
State Street
Massachusetts
$43.2M
4
Geode Capital Management
Geode Capital Management
Massachusetts
$30.4M
5
B
Braidwell
Connecticut
$113M

Top Sellers

1
Wellington Management Group
Wellington Management Group
Massachusetts
$68.1M
2
Capital World Investors
Capital World Investors
California
$20.5M
3
SC
Samlyn Capital
New York
$0
4
T. Rowe Price Investment Management
T. Rowe Price Investment Management
Maryland
$2.41M
5
LGM
Logos Global Management
California
$0
Name Holding Trade Value Shares
Change 		Shares
Change %
DCM
51
DAFNA Capital Management
California
$9.01M +$444K +14,200 +5%
ACM
52
ADAR1 Capital Management
Texas
$8.12M +$4.13M +131,955 +103%
GIM
53
Granahan Investment Management
Massachusetts
$7.51M +$1.76M +56,230 +31%
DnB Asset Management
54
DnB Asset Management
Norway
$7.33M +$146K +4,675 +2%
Federated Hermes
55
Federated Hermes
Pennsylvania
$7.28M – – –
NL
56
Nuveen LLC
North Carolina
$7.15M +$7.15M +228,567 New
Susquehanna International Group
57
Susquehanna International Group
Pennsylvania
$6.96M +$6.96M +222,352 New
PA
58
Perceptive Advisors
New York
$6.28M -$3.9M -124,533 -38%
GPP
59
Great Point Partners
Connecticut
$6.26M -$1.42M -45,272 -18%
Charles Schwab
60
Charles Schwab
California
$6.02M +$6.02M +192,242 New
FLAM
61
First Light Asset Management
Minnesota
$5.9M -$13.8M -439,537 -70%
Axa
62
Axa
France
$5.5M +$8.83K +282 +0.2%
State of Wisconsin Investment Board
63
State of Wisconsin Investment Board
Wisconsin
$5.47M +$2.43M +77,701 +80%
New York State Common Retirement Fund
64
New York State Common Retirement Fund
New York
$5.21M +$754K +24,100 +17%
FCMV
65
Foresite Capital Management VI
California
$5.01M +$5.01M +160,000 New
FCMI
66
Foresite Capital Management IV
California
$5.01M +$5.01M +160,000 New
NFT
67
Nan Fung Trinity
Hong Kong
$4.96M +$4.96M +158,605 New
UBS Group
68
UBS Group
Switzerland
$4.79M +$1.49M +47,725 +45%
Barclays
69
Barclays
United Kingdom
$4.78M +$4.18M +133,500 +693%
PHP
70
Parkman Healthcare Partners
Connecticut
$4.71M -$758K -24,203 -14%
Neuberger Berman Group
71
Neuberger Berman Group
New York
$4.61M +$3.21M +102,559 +229%
Royal Bank of Canada
72
Royal Bank of Canada
Ontario, Canada
$4.61M +$2.75M +87,860 +148%
D.E. Shaw & Co
73
D.E. Shaw & Co
New York
$4.44M -$326K -10,405 -7%
Schroder Investment Management Group
74
Schroder Investment Management Group
United Kingdom
$4.04M -$254K -8,118 -6%
Swiss National Bank
75
Swiss National Bank
Switzerland
$3.89M -$40.7K -1,300 -1%
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