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Xenon Pharmaceuticals
XENE

Overview Fund Activity

129 hedge funds and large institutions have $1.44B invested in Xenon Pharmaceuticals in 2021 Q4 according to their latest regulatory filings, with 37 funds opening new positions, 50 increasing their positions, 27 reducing their positions, and 24 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
129
Holders Change
+11
Holders Change %
+9.32%
% of All Funds
1.99%
Holding in Top 10
5
Holding in Top 10 Change
+3
Holding in Top 10 Change %
+150%
% of All Funds
0.08%
New
37
Increased
50
Reduced
27
Closed
24
Calls
$6.15M
Puts
$4.71M
Net Calls
+$1.44M
Net Calls Change
-$6.62M

Top Buyers

1
Point72 Asset Management
1
Point72 Asset Management
Connecticut
$93.5M
2
BI
2
BVF Inc
California
$103M
3
DCM
3
Driehaus Capital Management
Illinois
$97.6M
4
Lord, Abbett & Co
4
Lord, Abbett & Co
New Jersey
$56.1M
5
ACA
5
Avoro Capital Advisors
New York
$156M

Top Sellers

1
GTC
1
Ghost Tree Capital
New York
$3.12M
2
Adage Capital Partners
2
Adage Capital Partners
Massachusetts
$20.8M
3
NMC
3
NEA Management Company
Maryland
$0
4
SCM
4
Suvretta Capital Management
New York
$21.6M
5
BC
5
Boxer Capital
California
$18.7M
Name Holding Trade Value Shares
Change 		Shares
Change %
D.E. Shaw & Co
26
D.E. Shaw & Co
New York
$14.8M +$10.2M +326,261 +219%
DCM
27
DAFNA Capital Management
California
$12.6M -$121K -3,868 -1%
Renaissance Technologies
28
Renaissance Technologies
New York
$11.9M -$7.44M -238,200 -38%
SCM
29
Soleus Capital Management
Connecticut
$11.8M +$5.1M +163,300 +76%
PHP
30
Parkman Healthcare Partners
Connecticut
$11.3M +$1.54M +49,295 +16%
AllianceBernstein
31
AllianceBernstein
Tennessee
$9.19M +$968K +30,995 +12%
Invesco
32
Invesco
Georgia
$9.19M +$9.19M +294,100 New
Dimensional Fund Advisors
33
Dimensional Fund Advisors
Texas
$9.12M +$4.4M +140,749 +93%
Two Sigma Investments
34
Two Sigma Investments
New York
$8.7M +$3.39M +108,667 +64%
ACP
35
Acuta Capital Partners
California
$7.03M -$6.01M -192,409 -46%
GIM
36
Granahan Investment Management
Massachusetts
$6.79M +$4.17M +133,447 +159%
EP
37
Eversept Partners
New York
$6.55M +$6.55M +209,519 New
NFGH
38
Nan Fung Group Holdings
Hong Kong
$6.18M – – –
Axa
39
Axa
France
$6.09M +$1.11M +35,405 +22%
IC
40
Ikarian Capital
Texas
$5.6M -$6.2M -198,300 -53%
Goldman Sachs
41
Goldman Sachs
New York
$5.35M +$2.36M +75,409 +79%
AGA
42
Altrinsic Global Advisors
Connecticut
$5.31M – – –
State Street
43
State Street
Massachusetts
$5.04M +$431K +13,802 +9%
Vanguard Group
44
Vanguard Group
Pennsylvania
$4.79M +$1.44M +46,174 +43%
AAA
45
Affinity Asset Advisors
New York
$4.7M +$3.14M +100,500 +201%
Two Sigma Advisers
46
Two Sigma Advisers
New York
$3.96M -$1.54M -49,200 -28%
GTC
47
Ghost Tree Capital
New York
$3.12M -$21.6M -690,000 -87%
SCM
48
Silverarc Capital Management
Massachusetts
$3.12M +$2.52M +80,568 +415%
Millennium Management
49
Millennium Management
New York
$2.83M -$4.55M -145,598 -62%
SSA
50
Schonfeld Strategic Advisors
New York
$2.78M -$975K -31,221 -26%
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