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Xenon Pharmaceuticals

130 hedge funds and large institutions have $1.44B invested in Xenon Pharmaceuticals in 2021 Q4 according to their latest regulatory filings, with 38 funds opening new positions, 50 increasing their positions, 27 reducing their positions, and 24 closing their positions.

New
Increased
Maintained
Reduced
Closed

176% more capital invested

Capital invested by funds: $521M → $1.44B (+$916M)

150% more funds holding in top 10

Funds holding in top 10: 25 (+3)

85% more repeat investments, than reductions

Existing positions increased: 50 | Existing positions reduced: 27

58% more first-time investments, than exits

New positions opened: 38 | Existing positions closed: 24

31% more call options, than puts

Call options by funds: $6.15M | Put options by funds: $4.71M

10% more funds holding

Funds holding: 118130 (+12)

9.51% more ownership

Funds ownership: 82.93%92.44% (+9.5%)

Holders
130
Holders Change
+12
Holders Change %
+10.17%
% of All Funds
2%
Holding in Top 10
5
Holding in Top 10 Change
+3
Holding in Top 10 Change %
+150%
% of All Funds
0.08%
New
38
Increased
50
Reduced
27
Closed
24
Calls
$6.15M
Puts
$4.71M
Net Calls
+$1.44M
Net Calls Change
-$6.62M
Name Holding Trade Value Shares
Change
Change in
Stake
D.E. Shaw & Co
26
D.E. Shaw & Co
New York
$14.8M +$9.75M +326,261 +219%
DCM
27
DAFNA Capital Management
California
$12.6M -$116K -3,868 -1%
Renaissance Technologies
28
Renaissance Technologies
New York
$11.9M -$7.12M -238,200 -38%
SCM
29
Soleus Capital Management
Connecticut
$11.8M +$4.88M +163,300 +76%
PHP
30
Parkman Healthcare Partners
Connecticut
$11.3M +$1.47M +49,295 +16%
AllianceBernstein
31
AllianceBernstein
Tennessee
$9.19M +$926K +30,995 +12%
Invesco
32
Invesco
Georgia
$9.19M +$8.79M +294,100 New
Dimensional Fund Advisors
33
Dimensional Fund Advisors
Texas
$9.12M +$4.21M +140,749 +93%
Two Sigma Investments
34
Two Sigma Investments
New York
$8.7M +$3.25M +108,667 +64%
ACP
35
Acuta Capital Partners
California
$7.03M -$5.75M -192,409 -46%
GIM
36
Granahan Investment Management
Massachusetts
$6.79M +$3.99M +133,447 +159%
EP
37
Eversept Partners
New York
$6.55M +$6.26M +209,519 New
NFGH
38
Nan Fung Group Holdings
Hong Kong
$6.18M
Axa
39
Axa
France
$6.09M +$1.06M +35,405 +22%
IC
40
Ikarian Capital
Texas
$5.6M -$5.93M -198,300 -53%
Goldman Sachs
41
Goldman Sachs
New York
$5.35M +$2.25M +75,409 +79%
AGA
42
Altrinsic Global Advisors
Connecticut
$5.31M
State Street
43
State Street
Massachusetts
$5.04M +$412K +13,802 +9%
Vanguard Group
44
Vanguard Group
Pennsylvania
$4.79M +$1.38M +46,174 +43%
AAA
45
Affinity Asset Advisors
New York
$4.7M +$3M +100,500 +201%
Two Sigma Advisers
46
Two Sigma Advisers
New York
$3.96M -$1.47M -49,200 -28%
GTC
47
Ghost Tree Capital
New York
$3.12M -$20.6M -690,000 -87%
SCM
48
Silverarc Capital Management
Massachusetts
$3.12M +$2.41M +80,568 +415%
Millennium Management
49
Millennium Management
New York
$2.83M -$4.35M -145,598 -62%
SSA
50
Schonfeld Strategic Advisors
New York
$2.78M -$933K -31,221 -26%

XENE Hedge Fund Activity: Q4 2021 in Review

130 of the 6,498 institutional investors tracked by Wall St. Rank reported a position in Xenon Pharmaceuticals (XENE) for Q4 2021, worth a combined $1.44B — up 176% from $521M a quarter earlier.

Buyers outnumbered sellers: 38 funds opened new XENE positions and 24 closed out — a net gain of 14 holders — while 50 added to existing stakes and 27 trimmed.

The largest buyer was Point72 Asset Management, adding an estimated $57.2M. The largest seller was Ghost Tree Capital, cutting an estimated $20.6M.

  • 130 institutional investors held Xenon Pharmaceuticals (XENE) as of Q4 2021, up from 118 in Q3 2021.
  • Funds reported $1.44B of Xenon Pharmaceuticals stock for Q4 2021, up 176% quarter-over-quarter.
  • 38 funds opened new Xenon Pharmaceuticals positions in Q4 2021 and 24 closed out, a net change of +14 holders.
  • The largest Xenon Pharmaceuticals buyer in Q4 2021 was Point72 Asset Management, an estimated $57.2M added.
  • The largest Xenon Pharmaceuticals seller in Q4 2021 was Ghost Tree Capital, an estimated $20.6M sold.

Based on aggregated 13F filings for Q4 2021.