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Xenon Pharmaceuticals
XENE

Overview Fund Activity

205 hedge funds and large institutions have $2.6B invested in Xenon Pharmaceuticals in 2025 Q2 according to their latest regulatory filings, with 41 funds opening new positions, 77 increasing their positions, 55 reducing their positions, and 40 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
205
Holders Change
-1
Holders Change %
-0.49%
% of All Funds
2.75%
Holding in Top 10
10
Holding in Top 10 Change
-4
Holding in Top 10 Change %
-28.57%
% of All Funds
0.13%
New
41
Increased
77
Reduced
55
Closed
40
Calls
$11.4M
Puts
$9.75M
Net Calls
+$1.67M
Net Calls Change
-$6.22M

Top Buyers

1
BlackRock
BlackRock
New York
$168M
2
Holocene Advisors
Holocene Advisors
New York
$56.6M
3
State Street
State Street
Massachusetts
$43.2M
4
Geode Capital Management
Geode Capital Management
Massachusetts
$30.4M
5
B
Braidwell
Connecticut
$113M

Top Sellers

1
Wellington Management Group
Wellington Management Group
Massachusetts
$68.1M
2
Capital World Investors
Capital World Investors
California
$20.5M
3
SC
Samlyn Capital
New York
$0
4
T. Rowe Price Investment Management
T. Rowe Price Investment Management
Maryland
$2.41M
5
LGM
Logos Global Management
California
$0
Name Holding Trade Value Shares
Change 		Shares
Change %
OQS
226
Occudo Quantitative Strategies
Florida
– -$582K -16,975 Closed
Verition Fund Management
227
Verition Fund Management
Connecticut
– -$420K -12,508 Closed
YIH
228
Y-Intercept (HK)
Hong Kong
– -$401K -11,949 Closed
FRM
229
Fox Run Management
Connecticut
– -$382K -11,372 Closed
ACM
230
Aquatic Capital Management
Illinois
– -$353K -10,511 Closed
SCM
231
Silverarc Capital Management
Massachusetts
– -$340K -10,121 Closed
EC
232
EntryPoint Capital
New York
– -$298K -8,872 Closed
VA
233
Vident Advisory
Georgia
– -$221K -6,574 Closed
TC
234
TwinBeech Capital
New York
– -$216K -6,445 Closed
NIM
235
NEOS Investment Management
Connecticut
– -$205K -6,111 Closed
TE
236
Tema ETFs
New York
– -$205K -6,111 Closed
GC
237
Guggenheim Capital
Illinois
– -$202K -6,019 Closed
CCM
238
Coldstream Capital Management
Washington
– -$21.7K -648 Closed
PHK
239
Point72 Hong Kong
Hong Kong
– -$11K -329 Closed
Amundi
240
Amundi
France
– -$3.5K -114 Closed
PD
241
Point72 (DIFC)
United Arab Emirates
– -$2.21K -66 Closed
MPWT
242
MassMutual Private Wealth & Trust
Connecticut
– -$1.31K -39 Closed
CIBC Private Wealth Group
243
CIBC Private Wealth Group
Georgia
– -$1.1K -39 Closed
CA
244
Continuum Advisory
Idaho
– -$906 -27 Closed
TWD
245
True Wealth Design
Ohio
– -$302 -9 Closed
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