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Vertex Pharmaceuticals

1,747 hedge funds and large institutions have $119B invested in Vertex Pharmaceuticals in 2026 Q2 according to their latest regulatory filings, with 191 funds opening new positions, 704 increasing their positions, 616 reducing their positions, and 109 closing their positions.

New
Increased
Maintained
Reduced
Closed

75% more first-time investments, than exits

New positions opened: 191 | Existing positions closed: 109

14% more repeat investments, than reductions

Existing positions increased: 704 | Existing positions reduced: 616

13% more capital invested

Capital invested by funds: $106B → $119B (+$13.4B)

3% more funds holding

Funds holding: 1,6951,747 (+52)

1.38% more ownership

Funds ownership: 93.56%94.94% (+1.4%)

9% more call options, than puts

Call options by funds: $853M | Put options by funds: $783M

29% less funds holding in top 10

Funds holding in top 10: 1712 (-5)

Holders
1,747
Holders Change
+52
Holders Change %
+3.07%
% of All Funds
21.1%
Holding in Top 10
12
Holding in Top 10 Change
-5
Holding in Top 10 Change %
-29.41%
% of All Funds
0.14%
New
191
Increased
704
Reduced
616
Closed
109
Calls
$853M
Puts
$783M
Net Calls
+$69.7M
Net Calls Change
-$97.3M
Name Holding Trade Value Shares
Change
Change in
Stake
ASRS
201
Arizona State Retirement System
Arizona
$35.1M +$472K +1,065 +2%
PNC Financial Services Group
202
PNC Financial Services Group
Pennsylvania
$34.5M -$1.15M -2,584 -4%
SOMRS
203
State of Michigan Retirement System
Michigan
$33.7M -$576K -1,300 -2%
GIA
204
Gateway Investment Advisers
Ohio
$33.4M +$74.5K +168 +0.3%
SO
205
STRS Ohio
Ohio
$33.1M -$3.32M -7,484 -10%
Rafferty Asset Management
206
Rafferty Asset Management
New York
$32.7M +$4.98M +11,226 +21%
AWM
207
Apollon Wealth Management
South Carolina
$31.7M +$11.2M +25,315 +66%
SMDAM
208
Sumitomo Mitsui DS Asset Management
Japan
$31.5M -$218K -492 -0.8%
GFM
209
GF Fund Management
China
$31.1M -$848K -1,913 -3%
RIM
210
Rakuten Investment Management
Japan
$30.6M +$3.76M +8,493 +16%
AssetMark Inc
211
AssetMark Inc
California
$30.3M +$488K +1,101 +2%
TAM
212
Trillium Asset Management
Massachusetts
$29.9M -$17.6M -39,657 -40%
TAF
213
Tredje AP-fonden
Sweden
$29.5M -$6.36M -14,340 -19%
N
214
Natixis
France
$29.4M +$4.83M +10,903 +23%
FDCP
215
Foster Dykema Cabot & Partners
Massachusetts
$28.9M +$195K +441 +0.8%
MIM
216
MetLife Investment Management
New Jersey
$28.8M -$5.64M -12,732 -18%
II
217
IFM Investors
Australia
$28.7M +$2.94M +6,643 +13%
HJGA
218
Hardman Johnston Global Advisors
Connecticut
$28.7M -$299K -674 -1%
MLL
219
Moody Lynn & Lieberson
Massachusetts
$28.1M -$450K -1,016 -2%
Nisa Investment Advisors
220
Nisa Investment Advisors
Missouri
$28M -$766K -1,728 -3%
AP
221
Atwood & Palmer
Missouri
$28M +$268K +604 +1%
COPPSERS
222
Commonwealth of Pennsylvania Public School Employees Retirement System
Pennsylvania
$27.8M -$1.38M -3,108 -5%
HTHT
223
Hemenway Trust Hemenway Trust
New Hampshire
$27.8M +$1.99M +4,496 +9%
ZIM
224
Zacks Investment Management
Illinois
$27.3M -$13.3K -30 -0.1%
EIA
225
Edgemoor Investment Advisors
Maryland
$27.3M -$175K -395 -0.7%

VRTX Hedge Fund Activity: Q2 2026 in Review

1,747 of the 8,279 institutional investors tracked by Wall St. Rank reported a position in Vertex Pharmaceuticals (VRTX) for Q2 2026, worth a combined $119B — up 13% from $106B a quarter earlier.

Buyers outnumbered sellers: 191 funds opened new VRTX positions and 109 closed out — a net gain of 82 holders — while 704 added to existing stakes and 616 trimmed.

The largest buyer was Franklin Resources, adding an estimated $1.24B. The largest seller was Capital Research Global Investors, cutting an estimated $725M.

  • 1,747 institutional investors held Vertex Pharmaceuticals (VRTX) as of Q2 2026, up from 1,695 in Q1 2026.
  • Funds reported $119B of Vertex Pharmaceuticals stock for Q2 2026, up 13% quarter-over-quarter.
  • 191 funds opened new Vertex Pharmaceuticals positions in Q2 2026 and 109 closed out, a net change of +82 holders.
  • The largest Vertex Pharmaceuticals buyer in Q2 2026 was Franklin Resources, an estimated $1.24B added.
  • The largest Vertex Pharmaceuticals seller in Q2 2026 was Capital Research Global Investors, an estimated $725M sold.

Based on aggregated 13F filings for Q2 2026.