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Vertex Pharmaceuticals

1,747 hedge funds and large institutions have $119B invested in Vertex Pharmaceuticals in 2026 Q2 according to their latest regulatory filings, with 191 funds opening new positions, 704 increasing their positions, 616 reducing their positions, and 109 closing their positions.

New
Increased
Maintained
Reduced
Closed

75% more first-time investments, than exits

New positions opened: 191 | Existing positions closed: 109

14% more repeat investments, than reductions

Existing positions increased: 704 | Existing positions reduced: 616

13% more capital invested

Capital invested by funds: $106B → $119B (+$13.4B)

3% more funds holding

Funds holding: 1,6951,747 (+52)

1.38% more ownership

Funds ownership: 93.56%94.94% (+1.4%)

9% more call options, than puts

Call options by funds: $853M | Put options by funds: $783M

29% less funds holding in top 10

Funds holding in top 10: 1712 (-5)

Holders
1,747
Holders Change
+52
Holders Change %
+3.07%
% of All Funds
21.1%
Holding in Top 10
12
Holding in Top 10 Change
-5
Holding in Top 10 Change %
-29.41%
% of All Funds
0.14%
New
191
Increased
704
Reduced
616
Closed
109
Calls
$853M
Puts
$783M
Net Calls
+$69.7M
Net Calls Change
-$97.3M
Name Holding Trade Value Shares
Change
Change in
Stake
TI
176
Tidal Investments
Wisconsin
$47.5M +$1.6M +3,604 +4%
Kovitz Investment Group Partners
177
Kovitz Investment Group Partners
Illinois
$47.3M +$1.93M +4,361 +5%
PPF
178
PFA Pension Forsikringsaktieselskab
$46.7M -$18.2M -41,037 -30%
Lazard Asset Management
179
Lazard Asset Management
New York
$46.3M -$53.1M -119,844 -56%
State of Tennessee, Department of Treasury
180
State of Tennessee, Department of Treasury
Tennessee
$46.2M +$5.04M +11,364 +14%
SLAM
181
Swiss Life Asset Management
$45.5M +$4.01M +9,040 +11%
SPS
182
Susquehanna Portfolio Strategies
Pennsylvania
$45.2M +$27.4M +61,739 +212%
Janney Montgomery Scott
183
Janney Montgomery Scott
Pennsylvania
$42.6M +$625K +1,411 +2%
Toronto Dominion Bank
184
Toronto Dominion Bank
Ontario, Canada
$42.4M +$3.07M +6,919 +9%
AAIS
185
ABN AMRO Investment Solutions
$42M +$7.27M +16,415 +24%
RAM
186
Resona Asset Management
Japan
$41.8M -$2.76M -6,220 -7%
ECSS
187
Eurizon Capital SGR SpA
$41M +$476K +1,073 +1%
State of New Jersey Common Pension Fund D
188
State of New Jersey Common Pension Fund D
New Jersey
$40.9M -$1.98M -4,465 -5%
Fifth Third Bancorp
189
Fifth Third Bancorp
Ohio
$40.7M -$2.93M -6,601 -7%
Vontobel Holding
190
Vontobel Holding
Switzerland
$40.5M -$822K -1,855 -2%
LF
191
Lansforsakringar Fondforvaltning
Sweden
$39.6M -$1.87M -4,219 -5%
Cetera Investment Advisers
192
Cetera Investment Advisers
Illinois
$38.8M +$2.43M +5,474 +8%
EAM
193
Erste Asset Management
Austria
$38.2M -$6.83M -15,400 -17%
NAM
194
Nissay Asset Management
Japan
$37.6M +$1.9M +4,280 +6%
Calamos Advisors
195
Calamos Advisors
Illinois
$37.4M -$1.11M -2,498 -3%
MSV
196
MN Services Vermogensbeheer
Netherlands
$36.8M +$32.8M +74,100 New
Pacer Advisors
197
Pacer Advisors
Pennsylvania
$36M -$7.27M -16,398 -18%
CNB
198
Czech National Bank
Czech Republic
$35.9M +$1.36M +3,067 +4%
Daiwa Securities Group
199
Daiwa Securities Group
Japan
$35.5M +$1.77M +3,995 +6%
Capital Fund Management (CFM)
200
Capital Fund Management (CFM)
France
$35.3M -$23M -51,846 -42%

VRTX Hedge Fund Activity: Q2 2026 in Review

1,747 of the 8,279 institutional investors tracked by Wall St. Rank reported a position in Vertex Pharmaceuticals (VRTX) for Q2 2026, worth a combined $119B — up 13% from $106B a quarter earlier.

Buyers outnumbered sellers: 191 funds opened new VRTX positions and 109 closed out — a net gain of 82 holders — while 704 added to existing stakes and 616 trimmed.

The largest buyer was Franklin Resources, adding an estimated $1.24B. The largest seller was Capital Research Global Investors, cutting an estimated $725M.

  • 1,747 institutional investors held Vertex Pharmaceuticals (VRTX) as of Q2 2026, up from 1,695 in Q1 2026.
  • Funds reported $119B of Vertex Pharmaceuticals stock for Q2 2026, up 13% quarter-over-quarter.
  • 191 funds opened new Vertex Pharmaceuticals positions in Q2 2026 and 109 closed out, a net change of +82 holders.
  • The largest Vertex Pharmaceuticals buyer in Q2 2026 was Franklin Resources, an estimated $1.24B added.
  • The largest Vertex Pharmaceuticals seller in Q2 2026 was Capital Research Global Investors, an estimated $725M sold.

Based on aggregated 13F filings for Q2 2026.