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Vertex Pharmaceuticals

1,747 hedge funds and large institutions have $119B invested in Vertex Pharmaceuticals in 2026 Q2 according to their latest regulatory filings, with 191 funds opening new positions, 704 increasing their positions, 616 reducing their positions, and 109 closing their positions.

New
Increased
Maintained
Reduced
Closed

75% more first-time investments, than exits

New positions opened: 191 | Existing positions closed: 109

14% more repeat investments, than reductions

Existing positions increased: 704 | Existing positions reduced: 616

13% more capital invested

Capital invested by funds: $106B → $119B (+$13.4B)

3% more funds holding

Funds holding: 1,6951,747 (+52)

1.38% more ownership

Funds ownership: 93.56%94.94% (+1.4%)

9% more call options, than puts

Call options by funds: $853M | Put options by funds: $783M

29% less funds holding in top 10

Funds holding in top 10: 1712 (-5)

Holders
1,747
Holders Change
+52
Holders Change %
+3.07%
% of All Funds
21.1%
Holding in Top 10
12
Holding in Top 10 Change
-5
Holding in Top 10 Change %
-29.41%
% of All Funds
0.14%
New
191
Increased
704
Reduced
616
Closed
109
Calls
$853M
Puts
$783M
Net Calls
+$69.7M
Net Calls Change
-$97.3M
Name Holding Trade Value Shares
Change
Change in
Stake
SICM
1801
Sustainable Insight Capital Management
New York
-$326K -731 Closed
AOWM
1802
Asset One Wealth Management
Washington
-$301K -689 Closed
HH
1803
Hilltop Holdings
Texas
-$300K -671 Closed
HTC
1804
Haverford Trust Company
Pennsylvania
-$296K -663 Closed
GHAM
1805
Gilman Hill Asset Management
Connecticut
-$290K -650 Closed
KOC
1806
Koss-Olinger Consulting
Florida
-$288K -646 Closed
PEWA
1807
Pacific Excel Wealth Advisors
California
-$279K -625 Closed
FFM
1808
Fullerton Fund Management
Singapore
-$254K -568 Closed
AAMC
1809
Asset Allocation & Management Company
Illinois
-$253K -567 Closed
CWM
1810
Centurion Wealth Management
Virginia
-$251K -561 Closed
QT
1811
Quantbot Technologies
New York
-$248K -555 Closed
PFM
1812
Patton Fund Management
Texas
-$235K -526 Closed
EC
1813
EntryPoint Capital
New York
-$234K -523 Closed
VFG
1814
Victory Financial Group
Texas
-$231K -517 Closed
NWA
1815
New World Advisors
Massachusetts
-$230K -515 Closed
PAS
1816
Parsonex Advisory Services
Colorado
-$223K -499 Closed
HCM
1817
HMS Capital Management
Tennessee
-$222K -497 Closed
ST
1818
Sageworth Trust
Pennsylvania
-$215K -481 Closed
AF
1819
Aviso Financial
Ontario, Canada
-$213K -476 Closed
PIA
1820
Pinion Investment Advisors
Kansas
-$212K -475 Closed
TGY2IT
1821
Timothy G. Youngquist 2020 Irrevocable Trust
Florida
-$168K -376 Closed
GAG
1822
Goodman Advisory Group
Massachusetts
-$139K -311 Closed
TPWA
1823
Twin Peaks Wealth Advisors
California
-$125K -280 Closed
MR
1824
Munich Reinsurance
-$116K -260 Closed
CA
1825
Cache Advisors
California
-$103K -231 Closed

VRTX Hedge Fund Activity: Q2 2026 in Review

1,747 of the 8,279 institutional investors tracked by Wall St. Rank reported a position in Vertex Pharmaceuticals (VRTX) for Q2 2026, worth a combined $119B — up 13% from $106B a quarter earlier.

Buyers outnumbered sellers: 191 funds opened new VRTX positions and 109 closed out — a net gain of 82 holders — while 704 added to existing stakes and 616 trimmed.

The largest buyer was Franklin Resources, adding an estimated $1.24B. The largest seller was Capital Research Global Investors, cutting an estimated $725M.

  • 1,747 institutional investors held Vertex Pharmaceuticals (VRTX) as of Q2 2026, up from 1,695 in Q1 2026.
  • Funds reported $119B of Vertex Pharmaceuticals stock for Q2 2026, up 13% quarter-over-quarter.
  • 191 funds opened new Vertex Pharmaceuticals positions in Q2 2026 and 109 closed out, a net change of +82 holders.
  • The largest Vertex Pharmaceuticals buyer in Q2 2026 was Franklin Resources, an estimated $1.24B added.
  • The largest Vertex Pharmaceuticals seller in Q2 2026 was Capital Research Global Investors, an estimated $725M sold.

Based on aggregated 13F filings for Q2 2026.