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Vertex Pharmaceuticals

1,747 hedge funds and large institutions have $119B invested in Vertex Pharmaceuticals in 2026 Q2 according to their latest regulatory filings, with 191 funds opening new positions, 704 increasing their positions, 616 reducing their positions, and 109 closing their positions.

New
Increased
Maintained
Reduced
Closed

75% more first-time investments, than exits

New positions opened: 191 | Existing positions closed: 109

14% more repeat investments, than reductions

Existing positions increased: 704 | Existing positions reduced: 616

13% more capital invested

Capital invested by funds: $106B → $119B (+$13.4B)

3% more funds holding

Funds holding: 1,6951,747 (+52)

1.38% more ownership

Funds ownership: 93.56%94.94% (+1.4%)

9% more call options, than puts

Call options by funds: $853M | Put options by funds: $783M

29% less funds holding in top 10

Funds holding in top 10: 1712 (-5)

Holders
1,747
Holders Change
+52
Holders Change %
+3.07%
% of All Funds
21.1%
Holding in Top 10
12
Holding in Top 10 Change
-5
Holding in Top 10 Change %
-29.41%
% of All Funds
0.14%
New
191
Increased
704
Reduced
616
Closed
109
Calls
$853M
Puts
$783M
Net Calls
+$69.7M
Net Calls Change
-$97.3M
Name Holding Trade Value Shares
Change
Change in
Stake
ECM
1751
ExodusPoint Capital Management
New York
-$10M -22,403 Closed
XT
1752
XTX Topco
Cayman Islands
-$6.98M -15,632 Closed
TI
1753
Trexquant Investment
Connecticut
-$6.77M -15,171 Closed
ACM
1754
ADAR1 Capital Management
Texas
-$6.73M -15,075 Closed
SCM
1755
Superstring Capital Management
New York
-$4.92M -11,010 Closed
Group One Trading
1756
Group One Trading
Illinois
-$4.15M -9,357 Closed
EIA
1757
Emerald Investment Advisers
Pennsylvania
-$3.58M -8,012 Closed
Twin Tree Management
1758
Twin Tree Management
Texas
-$3.44M -7,769 Closed
VF
1759
Virtu Financial
New York
-$3.41M -7,634 Closed
FM
1760
Freemont Management
Switzerland
-$2.9M -6,500 Closed
HP
1761
Havemeyer Place
Connecticut
-$2.53M -5,655 Closed
FA
1762
Fiduciary Alliance
South Carolina
-$2.47M -5,583 Closed
CCIA
1763
Campbell & Co Investment Adviser
Maryland
-$2.49M -5,580 Closed
IMC Chicago
1764
IMC Chicago
Illinois
-$2.01M -4,533 Closed
Qube Research & Technologies (QRT)
1765
Qube Research & Technologies (QRT)
United Kingdom
-$1.77M -3,998 Closed
MFS
1766
Mattson Financial Services
Michigan
-$1.72M -3,861 Closed
DP
1767
Diadema Partners
New Jersey
-$1.71M -3,840 Closed
GP
1768
GLR Partners
Maryland
-$1.58M -3,538 Closed
AIP
1769
Arrowpoint Investment Partners
Singapore
-$1.52M -3,412 Closed
SP
1770
SWS Partners
Ohio
-$1.15M -2,573 Closed
OAM
1771
Oxford Asset Management
United Kingdom
-$1.12M -2,499 Closed
PL
1772
PeakShares LLC
Florida
-$1.1M -2,458 Closed
CC
1773
Centiva Capital
New York
-$959K -2,147 Closed
ORI
1774
Oak Ridge Investments
Illinois
-$897K -2,009 Closed
FC
1775
Farringdon Capital
United Kingdom
-$818K -1,831 Closed

VRTX Hedge Fund Activity: Q2 2026 in Review

1,747 of the 8,279 institutional investors tracked by Wall St. Rank reported a position in Vertex Pharmaceuticals (VRTX) for Q2 2026, worth a combined $119B — up 13% from $106B a quarter earlier.

Buyers outnumbered sellers: 191 funds opened new VRTX positions and 109 closed out — a net gain of 82 holders — while 704 added to existing stakes and 616 trimmed.

The largest buyer was Franklin Resources, adding an estimated $1.24B. The largest seller was Capital Research Global Investors, cutting an estimated $725M.

  • 1,747 institutional investors held Vertex Pharmaceuticals (VRTX) as of Q2 2026, up from 1,695 in Q1 2026.
  • Funds reported $119B of Vertex Pharmaceuticals stock for Q2 2026, up 13% quarter-over-quarter.
  • 191 funds opened new Vertex Pharmaceuticals positions in Q2 2026 and 109 closed out, a net change of +82 holders.
  • The largest Vertex Pharmaceuticals buyer in Q2 2026 was Franklin Resources, an estimated $1.24B added.
  • The largest Vertex Pharmaceuticals seller in Q2 2026 was Capital Research Global Investors, an estimated $725M sold.

Based on aggregated 13F filings for Q2 2026.