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Vertex Pharmaceuticals

1,747 hedge funds and large institutions have $119B invested in Vertex Pharmaceuticals in 2026 Q2 according to their latest regulatory filings, with 191 funds opening new positions, 704 increasing their positions, 616 reducing their positions, and 109 closing their positions.

New
Increased
Maintained
Reduced
Closed

75% more first-time investments, than exits

New positions opened: 191 | Existing positions closed: 109

14% more repeat investments, than reductions

Existing positions increased: 704 | Existing positions reduced: 616

13% more capital invested

Capital invested by funds: $106B → $119B (+$13.4B)

3% more funds holding

Funds holding: 1,6951,747 (+52)

1.38% more ownership

Funds ownership: 93.56%94.94% (+1.4%)

9% more call options, than puts

Call options by funds: $853M | Put options by funds: $783M

29% less funds holding in top 10

Funds holding in top 10: 1712 (-5)

Holders
1,747
Holders Change
+52
Holders Change %
+3.07%
% of All Funds
21.1%
Holding in Top 10
12
Holding in Top 10 Change
-5
Holding in Top 10 Change %
-29.41%
% of All Funds
0.14%
New
191
Increased
704
Reduced
616
Closed
109
Calls
$853M
Puts
$783M
Net Calls
+$69.7M
Net Calls Change
-$97.3M
Name Holding Trade Value Shares
Change
Change in
Stake
AG
1626
AmeriFlex Group
Nevada
$12.9K -$71.4K -161 -86%
CCM
1627
Chilton Capital Management
Texas
$12.9K -$14.2K -32 -55%
HI
1628
Hoey Investments
Pennsylvania
$12.9K +$1.33K +3 +13%
T
1629
Tidemark
California
$12.4K -$443 -1 -4%
MSG
1630
Main Street Group
Virginia
$12.4K
TLA
1631
Tanglewood Legacy Advisors
Texas
$12.4K
DF
1632
Dunhill Financial
United Kingdom
$11.9K -$443 -1 -4%
AS
1633
Altshuler Shaham
Israel
$11.9K +$6.65K +15 +167%
TF
1634
Tompkins Financial
New York
$11.9K +$10.6K +24 New
LFASL
1635
Lugano Financial Advisors SA (LFA)
Switzerland
$11.4K
DWS
1636
Dynamic Wealth Strategies
California
$10.9K
WA
1637
WestEnd Advisors
North Carolina
$10.9K +$1.33K +3 +16%
WA
1638
Westfuller Advisors
New York
$10.7K
CT
1639
Colonial Trust
South Carolina
$10.7K
VC
1640
Vestor Capital
Illinois
$10.5K +$23.8M +53,625 +26,547%
AP
1641
Aspect Partners
Virginia
$10.4K
CSC
1642
Caldwell Sutter Capital
California
$10.4K
CTC
1643
Cetera Trust Company
Minnesota
$10.4K
OCM
1644
Osterweis Capital Management
California
$10.4K
PCM
1645
Penserra Capital Management
California
$10K
JSAM
1646
J. Safra Asset Management
New York
$9.94K
M
1647
MOTCO
Texas
$9.44K +$2.22K +5 +36%
HFS
1648
Hughes Financial Services
Virginia
$9.44K +$3.99K +9 +90%
JGIA
1649
Jackson Grant Investment Advisers
Connecticut
$8.94K
AF
1650
Alerus Financial
North Dakota
$8.94K +$7.98K +18 New

VRTX Hedge Fund Activity: Q2 2026 in Review

1,747 of the 8,279 institutional investors tracked by Wall St. Rank reported a position in Vertex Pharmaceuticals (VRTX) for Q2 2026, worth a combined $119B — up 13% from $106B a quarter earlier.

Buyers outnumbered sellers: 191 funds opened new VRTX positions and 109 closed out — a net gain of 82 holders — while 704 added to existing stakes and 616 trimmed.

The largest buyer was Franklin Resources, adding an estimated $1.24B. The largest seller was Capital Research Global Investors, cutting an estimated $725M.

  • 1,747 institutional investors held Vertex Pharmaceuticals (VRTX) as of Q2 2026, up from 1,695 in Q1 2026.
  • Funds reported $119B of Vertex Pharmaceuticals stock for Q2 2026, up 13% quarter-over-quarter.
  • 191 funds opened new Vertex Pharmaceuticals positions in Q2 2026 and 109 closed out, a net change of +82 holders.
  • The largest Vertex Pharmaceuticals buyer in Q2 2026 was Franklin Resources, an estimated $1.24B added.
  • The largest Vertex Pharmaceuticals seller in Q2 2026 was Capital Research Global Investors, an estimated $725M sold.

Based on aggregated 13F filings for Q2 2026.